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Home > Art, Film & Photography > Thioxanthenes: Zuclopenthixol, Chlorprothixene, Flupentixol, Thioxanthene, Meprotixol, Pimethixene
Thioxanthenes: Zuclopenthixol, Chlorprothixene, Flupentixol, Thioxanthene, Meprotixol, Pimethixene

Thioxanthenes: Zuclopenthixol, Chlorprothixene, Flupentixol, Thioxanthene, Meprotixol, Pimethixene


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About the Book

Chapters: Zuclopenthixol, Chlorprothixene, Flupentixol, Thioxanthene, Meprotixol, Pimethixene. Source: Wikipedia. Pages: 26. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: Zuclopenthixol - Zuclopenthixol is available in three major preparations: It is also used in the treatment of acute bipolar mania. As a long acting injection, zuclopenthixol decanoate comes in a 200 mg and 500mg ampoule. Doses can vary from 50 mg 4 weekly to the maximum licensed dose of 600 mg weekly. In general, the lowest effective dose to prevent relapse is preferred. The interval may be shorter as a patient starts on the medication before extending to 3 weekly intervals subsequently. The dose should be reviewed and reduced in side effects occur, though in the short term an anticholinergic medication benztropine may be helpful for tremor and stiffness, while diazepam may be helpful for akathisia. 100 mg of zuclopenthixol decanoate is roughly equivalent to 20 mg of flupentixol decanoate or 12.5 mg of fluphenazine decanoate. In acutely psychotic and agitated inpatients, 50 - 200 mg of zuclopenthixol acetate may be given for a calming effect over the subsequent three days, with a maximum dose of 400 mg in total to be given. As it is a long-acting medication, care must be taken not to give an excessive dose. In oral form zuclopenthixol is available in 10, 25 and 40 mg tablets, with a dose range of 2060 mg daily. Zuclopenthixol mainly acts by antagonism of D1 and D2 receptors, though it also has some antihistamine effects, among other properties. Chronic administration of zuclopenthixol (30mg/kg/day for two years) in rats resulted in small, but significant, increases in the incidence of thyroid parafollicular carcinomas and, in females, of mammary adenocarcinomas and of pancreatic islet cell adenomas and carcinomas. An...More: http: //booksllc.net/?id=11671112


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Product Details
  • ISBN-13: 9781157493341
  • Publisher: Books LLC
  • Publisher Imprint: Books LLC
  • Height: 152 mm
  • No of Pages: 28
  • Spine Width: 2 mm
  • Weight: 54 gr
  • ISBN-10: 1157493343
  • Publisher Date: 15 Sep 2010
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Sub Title: Zuclopenthixol, Chlorprothixene, Flupentixol, Thioxanthene, Meprotixol, Pimethixene
  • Width: 229 mm


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