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Home > Art, Film & Photography > Antisense RNA Antisense RNA: Cis-Natural Antisense Transcript, Mipomersen, Spot 42 RNA, Rcis-Natural Antisense Transcript, Mipomersen, Spot 42 RNA, Rnai, Copa-Like RNA, Finp, Mi
Antisense RNA Antisense RNA: Cis-Natural Antisense Transcript, Mipomersen, Spot 42 RNA, Rcis-Natural Antisense Transcript, Mipomersen, Spot 42 RNA, Rnai, Copa-Like RNA, Finp, Mi

Antisense RNA Antisense RNA: Cis-Natural Antisense Transcript, Mipomersen, Spot 42 RNA, Rcis-Natural Antisense Transcript, Mipomersen, Spot 42 RNA, Rnai, Copa-Like RNA, Finp, Mi


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About the Book

Chapters: Cis-Natural Antisense Transcript, Mipomersen, Spot 42 Rna, Rnai, Copa-Like Rna, Finp, Micf Rna, Ctrna, Hotair, R1162-Like Plasmid Antisense Rna, Sar Rna. Source: Wikipedia. Pages: 38. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: Natural antisense transcripts (NATs) are a group of RNAs encoded within a cell that have transcript complementarity to other RNA transcripts. They have been identified in multiple eukaryotes, including humans, mice, yeast and Arabidopsis thaliana. This class of RNAs includes both protein-coding and non-coding RNAs. Current evidence has suggested a variety of regulatory roles for NATs, such as RNA interference (RNAi), alternative splicing, genomic imprinting, and X-chromosome inactivation. NATs are broadly grouped into two categories based on whether they act in cis or in trans. Trans-NATs are transcribed from a different location than their targets and usually have complementarity to multiple transcripts with some mismatches. MicroRNAs (miRNA) are an example of trans-NATs that can target multiple transcripts with a few mismatches. Cis-natural antisense transcripts (cis-NATs) on the other hand are transcribed from the same genomic locus as their target but from the opposite DNA strand and form perfect pairs. Figure 1: Orientations of cis-NATs within the genomeCis-NATs have a variety of orientations and differing lengths of overlap between pairs. There have been five identified orientations for cis-NATs to date. The most common orientation is head-to-head, where the 5' ends of both transcripts align together. This orientation would result in the greatest knockdown of gene expression if transcriptional collision is the reason for transcript inhibition. There is however some studies that have suggested that tail-to-tail orientations are the most common N...More: http: //booksllc.net/?id=1599354


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Product Details
  • ISBN-13: 9781157075608
  • Publisher: Books LLC
  • Publisher Imprint: Books LLC
  • Height: 152 mm
  • Sub Title: Cis-Natural Antisense Transcript, Mipomersen, Spot 42 RNA, Rcis-Natural Antisense Transcript, Mipomersen, Spot 42 RNA, Rnai, Copa-Like RNA, Finp, Mi
  • Width: 229 mm
  • ISBN-10: 1157075606
  • Publisher Date: 15 Sep 2010
  • Binding: Paperback
  • Spine Width: 3 mm
  • Weight: 73 gr


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Antisense RNA Antisense RNA: Cis-Natural Antisense Transcript, Mipomersen, Spot 42 RNA, Rcis-Natural Antisense Transcript, Mipomersen, Spot 42 RNA, Rnai, Copa-Like RNA, Finp, Mi
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