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Home > Art, Film & Photography > Laboratory Software: Blast, David, Blat, Whiskercontrol, Psi Protein Classifier, Primou
Laboratory Software: Blast, David, Blat, Whiskercontrol, Psi Protein Classifier, Primou

Laboratory Software: Blast, David, Blat, Whiskercontrol, Psi Protein Classifier, Primou


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About the Book

Chapters: Blast, David, Blat, Whiskercontrol, Psi Protein Classifier, Primou. Source: Wikipedia. Pages: 32. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: In bioinformatics, Basic Local Alignment Search Tool, or BLAST, is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of different proteins or the nucleotides of DNA sequences. A BLAST search enables a researcher to compare a query sequence with a library or database of sequences, and identify library sequences that resemble the query sequence above a certain threshold. For example, following the discovery of a previously unknown gene in the mouse, a scientist will typically perform a BLAST search of the human genome to see if humans carry a similar gene; BLAST will identify sequences in the human genome that resemble the mouse gene based on similarity of sequence. The BLAST program was designed by Eugene Myers, Stephen Altschul, Warren Gish, David J. Lipman and Webb Miller at the NIH and was published in J. Mol. Biol. in 1990. BLAST is one of the most widely used bioinformatics programs, because it addresses a fundamental problem and the algorithm emphasizes speed over sensitivity. This emphasis on speed is vital to making the algorithm practical on the huge genome databases currently available, although subsequent algorithms can be even faster. Before fast algorithms such as BLAST and FASTA were developed, doing database searches for the protein or nucleic sequences was very time consuming by using a full alignment procedure like Smith-Waterman. Indeed BLAST is faster than Smith-Waterman however, it cannot "guarantee the optimal alignments of the query and database sequences" as Smith-Waterman does, which "ensured the best performance on accuracy and the most precise results" at the ex...More: http: //booksllc.net/?id=36369


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Product Details
  • ISBN-13: 9781156845899
  • Publisher: Books LLC
  • Publisher Imprint: Books LLC
  • Height: 152 mm
  • Sub Title: Blast, David, Blat, Whiskercontrol, Psi Protein Classifier, Primou
  • Width: 229 mm
  • ISBN-10: 1156845890
  • Publisher Date: 15 Sep 2010
  • Binding: Paperback
  • Spine Width: 2 mm
  • Weight: 64 gr


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