About the Book
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 68. Chapters: Mutagen, Macromutation, DNA repair, Personalized medicine, Adaptive evolution in the human genome, Cat coat genetics, DbSNP, Mutationism, Evolution by Gene Duplication, BRCA mutation, Catecholaminergic polymorphic ventricular tachycardia, Evolution of influenza, Cat body type genetic mutation, Mutational robustness, 8p23.1 duplication syndrome, Adaptive mutation, Pyrimidine dimers, Indel, Silent mutation, Mutation rate, Loss of heterozygosity, ABC model of flower development, Synonymous substitution, Kraig Biocraft Laboratories, Frameshift mutation, Fusion gene, Seneca White Deer, F508, Nonsense mutation, NSP1, Depurination, Muller's morphs, Insertion, Sherman paradox, Selective sweep, Chimeric gene, Point mutation, Heteroplasmy, Dynamic mutation, Slipped strand mispairing, Missense mutation, Subfunctionalization, Homeosis, Mutation-selection balance, Transition, Leafy, Microheteroplasmy, Resistance mutation, PolymiRTS, Post-zygotic mutation, Micronucleus test, Fusion transcript, Functional element SNPs database, Germline STAT 1 Mutation, Neutral mutation, Founder mutation, Suppressor mutation, Genotoxicity, Splice site mutation, Mutation Frequency Decline, Segmental duplication, Homoplasmy, Transversion, Bud sport, Infinite-alleles model, Allelic heterogeneity, Rumpless, Polar effect. Excerpt: DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions in...