About the Book
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 37. Chapters: Atypical antipsychotics, D2 antagonists, Typical antipsychotics, Clozapine, Olanzapine, Quetiapine, Aripiprazole, Risperidone, PNU-99,194, Ziprasidone, Thioridazine, Metoclopramide, Clocapramine, Itopride, SB-277,011-A, Iloperidone, Sulpiride, Amisulpride, Lurasidone, Piquindone, Asenapine, Sertindole, Paliperidone, Olanzapine/fluoxetine, Blonanserin, Loxapine, Gevotroline, Perospirone, Bifeprunox, Bromopride, Spiperone, Carpipramine, Molindone, Zotepine, SKF-83,959, Remoxipride, Raclopride, Clebopride, AS-8112, Stepholidine, Alizapride, Dopamine antagonist, Mosapramine, L-745,870, Metitepine, Clotiapine, Cariprazine, Pipotiazine, Butaclamol, N-Methylspiperone, Eticlopride, Nafadotride, SCH 23390, Eglonyl, DHA-clozapine. Excerpt: Olanzapine (trade names Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera or in combination with fluoxetine Symbyax) is an atypical antipsychotic, approved by the FDA for the treatment of schizophrenia and bipolar disorder. Olanzapine is structurally similar to clozapine, but is classified as a thienobenzodiazepine. The olanzapine formulations are manufactured and marketed by the pharmaceutical company Eli Lilly and Company, whose patent for olanzapine proper expires in 2011 (in October 2009 a Canadian judge ruled that the 1991 patent was invalid). Sales of Zyprexa in 2008 were $2.2B in the US alone, and $4.7B in total. Known FDA approvals are as follows: Case-reports, open-label, and small pilot studies suggest efficacy of olanzapine for the treatment of some anxiety spectrum disorders (e.g. generalized anxiety disorder, panic disorder, delusional parasitosis, post-traumatic stress disorder); however, olanzapine has not been rigorously evaluated in randomized, placebo-controlled trials for this use and is not FDA approved for these indications. Other common off-label uses of olanzapin...
