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Home > Art, Film & Photography > Transdermal Patches: Emsam, Contraceptive Patch, Transdermal Patch, Duragesic, Nicotine Patch, Nicoderm, Daytrana, Estrogen Patch
Transdermal Patches: Emsam, Contraceptive Patch, Transdermal Patch, Duragesic, Nicotine Patch, Nicoderm, Daytrana, Estrogen Patch

Transdermal Patches: Emsam, Contraceptive Patch, Transdermal Patch, Duragesic, Nicotine Patch, Nicoderm, Daytrana, Estrogen Patch


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About the Book

Chapters: Emsam, Contraceptive Patch, Transdermal Patch, Duragesic, Nicotine Patch, Nicoderm, Daytrana, Estrogen Patch. Source: Wikipedia. Pages: 43. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: Emsam (selegiline transdermal system) is a transdermal patch using the monoamine oxidase inhibitor (MAOI) selegiline. Selegiline, in small doses, is most commonly used in the treatment of Parkinson's disease. It is also effective in higher doses for the treatment of major depressive disorder. On February 28, 2006 the U.S. Food and Drug Administration (FDA) approved EMSAM for the treatment of major depression. Emsam's development was spearheaded by J. Alexander Bodkin, M.D. , Director of the Clinical Psychopharmacology Research Program at McLean Hospital in Belmont MA, in conjunction with Harvard Medical School. Currently, it is the only MAOI on the market used in the treatment of depression that is absorbed through the skin into the blood stream and thereby to the central nervous system. The patch "is a matrix containing three layers consisting of a backing, an... adhesive drug layer, and a release liner that is placed against the skin." The primary advantage of delivering selegiline in this manner is to bypass the gastrointestinal tract and liver, specifically the small intestine, thereby limiting the chance of hypertensive crisis (very high spike in blood pressure possibly leading to stroke). "Despite long-standing concerns over hypertensive reactions,... (MAOIs) have grown in popularity... (and) the risk of hypertensive episodes is less than 1%." Due mainly to the availability of the newer SSRIs and SNRIs, which are viewed to have more medically benign side effects in the treatment of depression, psychopharmacologists and psychiatrists have avoided prescribing MAOIs because of the possibilit...More: http://booksllc.net/?id=4711367


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Product Details
  • ISBN-13: 9781156333464
  • Publisher: Books LLC
  • Publisher Imprint: Books LLC
  • Height: 152 mm
  • Sub Title: Emsam, Contraceptive Patch, Transdermal Patch, Duragesic, Nicotine Patch, Nicoderm, Daytrana, Estrogen Patch
  • Width: 229 mm
  • ISBN-10: 1156333466
  • Publisher Date: 15 Sep 2010
  • Binding: Paperback
  • Spine Width: 3 mm
  • Weight: 77 gr


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