About the Book
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 27. Chapters: Cysteine, Coenzyme A, Glutathione, Thiol, Acetylcysteine, Captopril, Metal dithiolene complex, Dimercaptosuccinic acid, Zinc pyrithione, Methanethiol, 2-Mercaptopyridine, 2-Mercaptoethanol, Thiophenol, Trypanothione, BDTH2, Dithiothreitol, Dimercaprol, Tert-Butylthiol, Penicillamine, 2,3-Dimercapto-1-propanesulfonic acid, Mesna, Butanethiol, Ammonium thioglycolate, 1,3-Propanedithiol, 1,2-Ethanedithiol, 1,2-Benzenedithiol, Coenzyme B, Mycothiol, Tiopronin, Benzyl mercaptan, Cysteamine, Grapefruit mercaptan, Thioglycolic acid, 9,10-Dithioanthracene, 3-Mercapto-3-methylbutan-1-ol, Phosphopantetheine, Thiosalicylic acid, Sodium maleonitriledithiolate, Dithioerythritol, Gemopatrilat, Bucillamine, Tixocortol, Omapatrilat, Coenzyme M, 1,2-Propanedithiol, Bacillithiol, 3-Mercapto-1-propanesulfonic acid, Thiorphan, 3-Mercaptopropane-1,2-diol, Dihydrolipoic acid, Dihydrolipoamide, 3-Mercaptopyruvic acid, 2-Mercaptoindole, Thiomalic acid, Rentiapril. Excerpt: Glutathione (GSH) is a tripeptide that contains an unusual peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. It is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides. Thiol groups are reducing agents, existing at a concentration of approximately 5 mM in animal cells. Glutathione reduces disulfide bonds formed within cytoplasmic proteins to cysteines by serving as an electron donor. In the process, glutathione is converted to its oxidized form glutathione disulfide (GSSG), also called L(-)-Glutathione. Glutathione is found almost exclusively in its reduced form, since the enzyme that reverts it from its oxidized form, glutathione reductase, is constitutively active and inducib...
