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Home > Art, Film & Photography > EC 3.1.2: Ubiquitin Carboxy-Terminal Hydrolase L1, Palmitoyl-Coa Hydrolase, Palmitoyl(protein) Hydrolase
EC 3.1.2: Ubiquitin Carboxy-Terminal Hydrolase L1, Palmitoyl-Coa Hydrolase, Palmitoyl(protein) Hydrolase

EC 3.1.2: Ubiquitin Carboxy-Terminal Hydrolase L1, Palmitoyl-Coa Hydrolase, Palmitoyl(protein) Hydrolase


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About the Book

Chapters: Ubiquitin Carboxy-Terminal Hydrolase L1, Palmitoyl-Coa Hydrolase, Palmitoyl(protein) Hydrolase, Oleoyl-(acyl-Carrier-Protein) Hydrolase, Dodecanoyl-(acyl-Carrier-Protein) Hydrolase, 4-Hydroxybenzoyl-Coa Thioesterase, Choloyl-Coa Hydrolase, Adp-Dependent Short-Chain-Acyl-Coa Hydrolase, S-Formylglutathione Hydrolase, Phenylacetyl-Coa Hydrolase, Acetoacetyl-Coa Hydrolase, Adp-Dependent Medium-Chain-Acyl-Coa Hydrolase, 3-Hydroxyisobutyryl-Coa Hydrolase, Hydroxymethylglutaryl-Coa Hydrolase, Hydroxyacylglutathione Hydrolase, S-Succinylglutathione Hydrolase, Citrate Lyase Deacetylase, (S)-Methylmalonyl-Coa Hydrolase, Formyl-Coa Hydrolase, Succinyl-Coa Hydrolase, Bile-Acid-Coa Hydrolase, Glutathione Thiolesterase. Source: Wikipedia. Pages: 58. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: Ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) (EC 3.1.2.15) is a deubiqutinating enzyme. UCHL1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons. A point mutation (I93M) in the gene encoding this protein is implicated as the cause of Parkinson's disease in one kindred. Furthermore, a polymorphism (S18Y) in this gene has been found to be associated with a reduced risk for Parkinson's disease. The gene is also associated with the Alzheimer's disease, and required for normal synaptic and cognitive function. Human UCH-L1 and the closely related protein UCHL3 have the most complicated knot structure yet discovered for a protein, with five knot crossings. It is speculated that a knot structure may increase a protein's resistance to degradation in the proteasome. Ubiquitin carboxy-ter...More: http: //booksllc.net/?id=931501


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Product Details
  • ISBN-13: 9781155527802
  • Publisher: Books LLC
  • Publisher Imprint: Books LLC
  • Height: 152 mm
  • Sub Title: Ubiquitin Carboxy-Terminal Hydrolase L1, Palmitoyl-Coa Hydrolase, Palmitoyl(protein) Hydrolase
  • Width: 229 mm
  • ISBN-10: 1155527801
  • Publisher Date: 15 Sep 2010
  • Binding: Paperback
  • Spine Width: 4 mm
  • Weight: 100 gr


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