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Home > Art, Film & Photography > Sulfoxides: Modafinil, Dimethyl Sulfoxide, Omeprazole, Esomeprazole, Lansoprazole, Tenatoprazole, Pantoprazole, Rabeprazole, Adrafinil
Sulfoxides: Modafinil, Dimethyl Sulfoxide, Omeprazole, Esomeprazole, Lansoprazole, Tenatoprazole, Pantoprazole, Rabeprazole, Adrafinil

Sulfoxides: Modafinil, Dimethyl Sulfoxide, Omeprazole, Esomeprazole, Lansoprazole, Tenatoprazole, Pantoprazole, Rabeprazole, Adrafinil


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About the Book

Purchase includes free access to book updates online and a free trial membership in the publisher's book club where you can select from more than a million books without charge. Chapters: Modafinil, Dimethyl Sulfoxide, Omeprazole, Esomeprazole, Lansoprazole, Tenatoprazole, Pantoprazole, Rabeprazole, Adrafinil, Sulfoxide, Dexlansoprazole, Armodafinil, Gr-159,897, Flosequinan, Mesoridazine, Crl-40,941, Diethyl Sulfoxide. Excerpt: Adrafinil ( CRL-40028 ) is a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention in elderly patients. It is also used off-label by individuals wishing to avoid fatigue, such as night workers or others who need to stay awake and alert for long periods of time. Adrafinil is a prodrug; it is primarily metabolized in vivo to modafinil ( Provigil ), resulting in nearly identical pharmacological effects. Unlike modafinil, however, it takes time for the metabolite to accumulate to active levels in the bloodstream. Effects usually are apparent within 45 60 minutes when taken orally on an empty stomach . Adrafinil, also known by the codename CRL 40028, has as its chemical name 2-(Diphenylmethyl) sulfinyl acetohydroxamic acid. Its molecular formula is n5H15NO3S. The drug's molecular weight is 289.4 Daltons . Adrafinil does not currently have FDA approval and is thus unregulated in the United States, although it is used in France and elsewhere in Europe . The drug is marketed under the brand name Olmifon as a racemate with a stereogenic centre at the sulfur atom. History Adrafinil was discovered in the late 1970s by scientists working with the French pharmaceutical company Group Lafon. First offered in France in 1986 as an experimental treatment for narcolepsy, Lafon later developed modafinil, the primary metabolite of adrafinil. Modafinil possesses greater selective alpha-1 adrenergic activity than adrafinil without the side effects of stomach pain, skin irritations, feelings of tension, and increase...


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Product Details
  • ISBN-13: 9781155283678
  • Publisher: Books LLC
  • Publisher Imprint: Books LLC
  • Height: 152 mm
  • No of Pages: 92
  • Spine Width: 6 mm
  • Weight: 145 gr
  • ISBN-10: 1155283678
  • Publisher Date: 02 May 2010
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Sub Title: Modafinil, Dimethyl Sulfoxide, Omeprazole, Esomeprazole, Lansoprazole, Tenatoprazole, Pantoprazole, Rabeprazole, Adrafinil
  • Width: 229 mm


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