Coronavirus Disease 2019 (Covid-19): A Clinical Guide

CORONAVIRUS DISEASE 2019 (COVID-19) Provides comprehensive coverage of all key aspects of COVID-19, including: etiology, diagnosis, symptomatology, management, and treatment Coronavirus Disease 2019 (COVID-19): A Clinical Guide provides healthcare professionals at all levels with up-to-date knowledge about the clinical, epidemiological, genomic, virological, and radiologic features of COVID-19. Consolidating multiple systematic reviews and meta-analyses into a single volume, this comprehensive textbook also addresses health policies, mass casualty planning, healthcare worker safety, economic impact, lessons for future outbreaks, and other para-clinical and social aspects of the COVID-19 pandemic. The text presents a thorough summary and critical analysis of COVID-19 based on an exhaustive review of recently published literature and data. Topics include the virologic characteristics of SARS-CoV-2, pulmonary and extrapulmonary manifestations and consequences of COVID-19, prevention and transmission control, the pandemic’s indirect impact to the care and management of other diseases, passive immunotherapy and its implications, diagnostic and treatment approaches for critically ill patients, and more. Edited by leading ­practitioners at the forefront of COVID-19 research, this invaluable resource: Integrates clinical, radiological, and epidemiological data and discussion of prevention, diagnosis, and treatment Reviews the epidemiology, mechanisms of action, manifestations, and management of cardiovascular, neurological, and pulmonary diseases associated with COVID-19 Covers diagnostic technologies, includes radiologic imaging, and RT-PCR testing Explores therapeutic approaches for managing a variety of complications Discusses post-vaccination symptom management and implications of immunization Addresses COVID-19 in pediatrics, in cancer patients, and in patients with lung disease, diabetes, ­hypertension, obesity, and other underlying conditions Coronavirus Disease 2019 (COVID-19): A Clinical Guide is an indispensable source of information for all clinicians, researchers, epidemiologists, nurses, radiologists, and healthcare managers working to address any aspect of the COVID-19 pandemic.

Table of Contents:
List of Contributors x Preface xvii 1 COVID-19: Epidemiology 1 Phillip Quiroz, George W. Rutherford, and Michael P. Dube 2 COVID-19: Virology 22 Saeideh Najafi, Salar Tofighi, and Juliana Sobczyk 3 COVID-19: Laboratory/Serologic Diagnostics 34 Desmond Chin, Liesl S. Eibschutz, Juliana Sobczyk, Mobin Azami, Michael Jovan Repajic, and Michael P. Dube 4 COVID-19: Radiologic Diagnosis 61 Brian P. Pogatchnik, Wakana Murakami, and Shabnam Mortazavi 5 COVID-19: Pathology Perspective 101 Elham Hatami, Hana Russo, and Grace Y. Lin 6 COVID-19: Immunology 112 Yasaswi V. Vengalasetti, Niyousha Naderi, Christian Vega, Akhilesh Kumar, and Andrew T. Catanzaro 7 COVID-19: Presentation and Symptomatology 125 Jacek Czubak, Karolina Stolarczyk, Marcin Fraczek, Katarzyna Resler, Anna Orzel, Wojciech Flieger, and Tomasz Zatonìski 8 COVID-19: Risk Stratification 149 Dominique Duncan, Rachael Garner, and Yujia Zhang 9 COVID-19: Outpatient Management in Adults 165 Michael P. Dubé 10 COVID-19: Inpatient Management 182 Angelena Lopez, Yuri Matusov, Isabel Pedraza, Victor Tapson, Jeremy Falk, and Peter Chen 11 COVID-19: ICU and Critical Care Management 233 Daniel Crouch, Alexandra Rose, Cameron McGuire, Jenny Yang, Mazen Odish, and Amy Bellinghausen 12 COVID-19 in Pediatrics 255 Erlinda R. Ulloa, Kaidi He, Erin Chung, Delma Nieves, David E. Michalik, and Behnoosh Afghani 13 Pharmacologic Therapeutics for COVID-19 290 Amanda M. Burkhardt, Angela Lu, Isaac Asante, and Stan Louie 14 Co-infections and Secondary Infections in COVID-19 Pneumonia 319 Sanaz Katal, Liesl S. Eibschutz, Amit Gupta, Sean K. Johnston, Lucia Flors, and Ali Gholamrezanezhad 15 COVID-19: Neurology Perspective 339 Kiandokht Keyhanian, Raffaella Pizzolato Umeton, Babak Mohit, Brooke McNeilly, and Mehdi Ghasemi 16 COVID-19: Cardiology Perspective 361 Michael DiVita, Meshe Chonde, Megan Kamath, Darko Vucicevic, Ashley M. Fan, Arnold S. Baas, and Jeffrey J. Hsu 17 COVID-19: Oncologic and Hematologic Considerations 389 Diana L. Hanna, Caroline I. Piatek, Binh T. Ngo, and Heinz-Josef Lenz 18 COVID-19: Dermatology Perspective 409 Sabha Mushtaq, Fabrizio Fantini, and Sebastiano Recalcati 19 COVID-19: Ophthalmology Perspective 417 Hashem Al-Marzouki, Benjamin P. Hammond, Wendy W. Huang, and Angela N. Buffenn 20 COVID-19: Nutrition Perspectives 428 Emma J. Ridley, Lee-anne S. Chapple, Aidan Burrell, Kate Fetterplace, Amy Freeman-Sanderson, Andrea P. Marshall, and Ary Serpa Neto 21 COVID-19: Nursing Perspective 454 Michelle Zappas, Dalia Copti, Cynthia Sanchez, Janett A. Hildebrand, and Sharon O'Neill 22 COVID-19 Vaccination 472 Anurag Singh, Simran P. Kaur, Mohd Fardeen Husain Shahanshah, Bhawna Sharma, Vijay K. Chaudhary, Sanjay Gupta, and Vandana Gupta 23 Post-COVID-19 Vaccine Imaging Findings 494 Shadi Asadollahi, Liesl S. Eibschutz, Sanaz Katal, Vorada Sakulsaengprapha, Yasaswi Vengalasetti, Nikoo Saeedi, Sean K. Johnston, and Jennifer H. Johnston 24 COVID-19: Long-Term Pulmonary Consequences 515 Liesl S. Eibschutz, Tianyuan Fu, Boniface Yarabe, Narges Jokar, Sanaz Katal, Charlotte Sackett, Michael Repajic, and Ching-Fei Chang 25 Psychological Effects and Neuropsychiatric Sequelae in COVID-19 Patients 539 Elpitha Sakka, Arturas Kalniunas, Elzbieta Vitkauskaite, Wala Salman, Subhana Chaudhri, and Sofia Pappa 26 Mental Health Effects of the COVID-19 Pandemic on Healthcare Professionals 554 Liesl S. Eibschutz, Charlotte Sackett, Vorada Sakulsaengprapha, Masoomeh Faghankhani, Glenn Baumann, and Sofia Pappa 27 COVID-19: Ethical Considerations in Clinical Practice 580 Kiarash Aramesh 28 Racial, Ethnic, and Other Disparities in the Epidemiology and Care of COVID-19 586 Liesl S. Eibschutz, Charlotte Sackett, Kalpana Dave, Sarah Cherukury, Christian Vega, Mauricio Bueno, and Hector Flores 29 Global Impact of COVID-19 on Healthcare Systems 615 Liesl S. Eibschutz, Alexander A. Bruckhaus, Alexis Bennett, Dominique Duncan, Charlotte Sackett, Kalpana Dave, Sarah Cherukury, Victoria Uram, and Calvin M. Smith 30 COVID-19: Mass Casualty Planning 651 Lee Myers Index 658

About the Author :
Ali Gholamrezanezhad, Associate Professor of Clinical Imaging, Keck School of Medicine, University of Southern California (USC), Los Angeles, California, USA. Since the outbreak of the pandemic, Dr. Gholamrezanezhad has been leading an international team of researchers, physicians, and scientists to investigate COVID-19. Michael P. Dube, Professor of Medicine, Division of Infectious Diseases, Keck School of Medicine, University of Southern California (USC), Los Angeles, California, USA. Dr. Dube has been active in clinical care and clinical trials of COVID-19 therapeutics and vaccines and serves on a variety of committees at the local and state levels addressing the pandemic.