Stem-Cell Nanoengineering

Stem Cell Nanoengineering reviews the applications of nanotechnology in the fields of stem cells, tissue engineering, and regenerative medicine. Topics addressed include various types of stem cells, underlying principles of nanobiotechnology, the making of nano-scaffolds, nano tissue engineering, applications of nanotechnology in stem cell tracking and molecular imaging, nano-devices, as well as stem cell nano-engineering from bench to bedside. Written by renowned experts in their respective fields, chapters describe and explore a wide variety of topics in stem cell nanoengineering, making the book a valuable resource for both researchers and clinicians in biomedical and bioengineering fields.

Table of Contents:
About the Editors ix Contributors xi Preface xvii Part 1 An Introduction to Stem Cells 1 1 Adult Stem Cells 3 Andreas Nussler and Sahar Olsadat Sajadian 2 Pluripotent Stem Cells 25 Hossein Azizi, Akbar Hajizadeh Moghaddam, and Thomas Skutella 3 Interactions of Stem Cells and Components of the Extracellular Matrix 35 Anna K. Blakney, Julie J. Antetomaso, Winnie W. Leung, and Deok-Ho Kim 4 Regenerative Medicine and Cell Therapy: Past, Present, and Future 47 Hooman Sadri-Ardekani and Anthony Atala Part 2 An Introduction to Nanotechnology 67 5 Principles of Nanotechnology 69 Jerzy Leszczynski 6 Stem-Cell Nanoengineering: Explorations in a Rapidly Moving Field 87 Abhalaxmi Singh and Sanjeeb K. Sahoo Part 3 Nanostructures for Stem-Cell Engineering – Engineering Approach 97 7 Nanopatterned Surfaces for Stem-Cell Engineering 99 Waleed Ahmed El-Said, Tae-Hyung Kim, Ki-Bum Lee, and Jeong-Woo Choi 8 Biomimetic Nanostructures by Electrospinning and Electrospraying 123 Elham Vatankhah, Molamma P. Prabhakaran, and Seeram Ramakrishna 9 Nanoparticles for Stem-Cell Engineering 143 Esmaiel Jabbari 10 Toxicology of Nanobiomaterials 171 Shahin Bonakdar and Omid Mashinchian Part 4 Control of Stem-Cell Fate by Engineering of Microenvironment 185 11 Stem-Cell Responses to Surface Nanotopographies 187 Peng-Yuan Wang and Wei-Bor Tsai 12 Control of Mesenchymal Stem-Cell Fate by Engineering the Nanoenvironment 205 Habib Nikukar, Stuart Reid, Mathis O. Riehle, Adam S.G. Curtis, and Matthew J. Dalby 13 Delivery of Molecules and Genes/Small Interfering RNA into Stem Cells by Nanoengineering 223 Mohsen Ashjari Part 5 Nanotissue Engineering – Biological Approach along with Differentiation 243 14 Expansion of Stem Cells by Nanotissue Engineering 245 Amir Mellati and Hu Zhang 15 Nanotissue Engineering of Neural Cells 265 Sasan Jalili-Firoozinezhad, Fahimeh Mirakhori, and Hossein Baharvand 16 Nanotechnology and Cardiovascular Tissue Engineering 285 Savneet Kaur and Upasana Rishiraj 17 Nanotissue Engineering of Musculoskeletal Cells 299 Mohamadreza Baghaban Eslaminejad, Leila Taghiyar, and Fatemeh Safari 18 Nanotissue Engineering of Skin Cells 315 Daisy M. Ramos, Aditi Subramanian, Aja Aravamudhan, Matthew Harmon, Roshan James, Namdev B. Shelke, and Sangamesh G. Kumbar 19 High-Throughput Screening of Stem Cell Self-Renewal and Differentiation on Nanomaterials 327 Perry T. Yin, Tae-Hyung Kim, Jeong-Woo Choi, and Ki-Bum Lee Part 6 Nanotechnology in Stem-Cell Imaging 345 20 Nanotechnology for Cellular Imaging 347 Miroslaw Janowski, P. Walczak, and J.W.M. Bulte Part 7 Nanotissue Engineering and Clinical Applications 363 21 Advancing Translational Nanotechnology to Clinical Application 365 Michelle Griffin, Shima Salmasi, Naghmeh Naderi, Peter E. Butler, and Alexander M. Seifalian 22 Stem-Cell Nanoengineering from Bench to Bed 381 Omid Mashinchian, Shahin Bonakdar, Shahriar Sharifi, and Morteza Mahmoudi Index 397

About the Author :
Hossein Baharvand, PhD, is a Professor and Director of Royan Institute for Stem Cell Biology and Technology, Cell Science Research Center, ACECR, Tehran, Iran. Dr. Baharvand is also Head of the Department of Developmental Biology at the University of Science and Culture, ACECR, Tehran, Iran. Nasser Aghdami, MD, PhD is an Associate Professor and Head of the Department of Regenerative Medicine at the Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran. Dr. Aghdami is also Head of Royan Cell Therapy Center, ACECR, Tehran, Iran.