Glial Physiology and Pathophysiology
Home > Mathematics and Science Textbooks > Biology, life sciences > Life sciences: general issues > Neurosciences > Glial Physiology and Pathophysiology
Glial Physiology and Pathophysiology

Glial Physiology and Pathophysiology


     0     
5
4
3
2
1



Out of Stock


Notify me when this book is in stock
X
About the Book

Table of Contents:
Preface xvii About the Authors xxi Abbreviations xxv About the Companion Website xxxii 1 History of Neuroscience and the Dawn of Research in Neuroglia 1 1.1 The miraculous human brain: localising the brain functions 1 1.2 Cellular organisation of the brain 10 1.3 Mechanisms of communications in neural networks 14 1.4 The concept of neuroglia 27 1.5 Beginning of the modern era 47 1.6 Concluding remarks 49 References 49 2 General Overview of Signalling in the Nervous System 59 2.1 Intercellular signalling: wiring and volume modes of transmission 59 2.2 Cellular signalling: receptors 62 2.3 Intracellular signalling: second messengers 67 2.4 Calcium signalling 67 2.5 Concluding remarks 72 3 Neuroglia: Definition, Classification, Evolution, Numbers, Development 73 3.1 Definition of neuroglia as homeostatic cells of the nervous system 74 3.2 Classification 75 3.3 Evolution of neuroglia 76 3.4 Numbers: how many glial cells are in the brain? 93 3.5 Embryogenesis and development of neuroglia in mammals 96 3.6 Concluding remarks 99 References 100 4 Astroglia 105 4.1 Definition and heterogeneity 107 4.2 Morphology of the main types of astroglia 113 4.3 How to identify astrocytes in the nervous tissue 119 4.4 Astroglial syncytial networks 120 4.5 Physiology of astroglia 125 4.6 Functions of astroglia 175 4.7 Concluding remarks 231 References 231 5 Oligodendrocytes 245 5.1 Oligodendrocyte anatomy 247 5.2 Myelin structure and function 252 5.3 Physiology of oligodendrocytes 266 5.4 Oligodendrocyte development 283 5.5 Concluding remarks 299 References 299 6 NG2-glial Cells 321 6.1 Definition of NG2-glia 321 6.2 Structure of NG2-glia 324 6.3 Physiology of NG2-glia 327 6.4 Proliferation of NG2-glia and generation of oligodendrocytes 332 6.5 Relationship between NG2-glia and CNS pericytes 333 6.6 Evolution of NG2-glia 336 6.7 Concluding remarks 337 References 337 7 Microglia 343 7.1 Definition of microglia 344 7.2 Microglial origin and development 345 7.3 Morphology of microglia 345 7.4 General physiology of microglia 351 7.5 Microglial migration and motility 372 7.6 Physiological functions of microglia: role in synaptic transmission and plasticity 373 7.7 Microglia in ageing 375 7.8 Concluding remarks 375 References 376 8 Peripheral Glial Cells 381 8.1 Peripheral nervous system 382 8.2 Schwann cells 390 8.3 Satellite glial cells 407 8.4 Enteric glia 412 8.5 Olfactory ensheathing cells (OECs) 418 8.6 Concluding remarks 422 References 423 9 General Pathophysiology of Neuroglia 431 9.1 Neurological disorders as gliopathologies 431 9.2 Reactive astrogliosis 433 9.3 Wallerian degeneration 439 9.4 Excitotoxic vulnerability of oligodendrocytes: the death of white matter 442 9.5 Activation of microglia 444 9.6 Concluding remarks 449 References 450 10 Neuroglia in Neurological Diseases 453 10.1 Introduction 454 10.2 Genetic astrogliopathology: Alexander disease 456 10.3 Stroke and ischaemia 458 10.4 Migraine and spreading depression 467 10.5 CNS oedema 469 10.6 Metabolic disorders 471 10.7 Toxic encephalopathies 473 10.8 Neurodegenerative diseases 474 10.9 Leukodystrophies 487 10.10 Epilepsy 488 10.11 Psychiatric diseases 490 10.12 Autistic disorders 491 10.13 Neuropathic pain 492 10.14 Demyelinating diseases 494 10.15 Infectious diseases 496 10.16 Peripheral neuropathies 499 10.17 Gliomas 501 10.18 Concluding remarks 504 References 504 Author Index 513 Subject Index 517

About the Author :
Alexei Verkhratsky is Professor of Neurophysiology and Chairman of the Division of Neuroscience at the University of Manchester, UK. Arthur Butt is Professor of Cellular Neurophysiology, Department of Pharmacy and Biomedical Sciences, University of Portsmouth, UK.


Best Sellers


Product Details
  • ISBN-13: 9781118402030
  • Publisher: John Wiley & Sons Inc
  • Publisher Imprint: Wiley-Blackwell
  • Language: English
  • ISBN-10: 1118402030
  • Publisher Date: 31 Jan 2013
  • Binding: Digital (delivered electronically)
  • No of Pages: 560


Similar Products

Add Photo
Add Photo

Customer Reviews

REVIEWS      0     
Click Here To Be The First to Review this Product
Glial Physiology and Pathophysiology
John Wiley & Sons Inc -
Glial Physiology and Pathophysiology
Writing guidlines
We want to publish your review, so please:
  • keep your review on the product. Review's that defame author's character will be rejected.
  • Keep your review focused on the product.
  • Avoid writing about customer service. contact us instead if you have issue requiring immediate attention.
  • Refrain from mentioning competitors or the specific price you paid for the product.
  • Do not include any personally identifiable information, such as full names.

Glial Physiology and Pathophysiology

Required fields are marked with *

Review Title*
Review
    Add Photo Add up to 6 photos
    Would you recommend this product to a friend?
    Tag this Book Read more
    Does your review contain spoilers?
    What type of reader best describes you?
    I agree to the terms & conditions
    You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

    CUSTOMER RATINGS AND REVIEWS AND QUESTIONS AND ANSWERS TERMS OF USE

    These Terms of Use govern your conduct associated with the Customer Ratings and Reviews and/or Questions and Answers service offered by Bookswagon (the "CRR Service").


    By submitting any content to Bookswagon, you guarantee that:
    • You are the sole author and owner of the intellectual property rights in the content;
    • All "moral rights" that you may have in such content have been voluntarily waived by you;
    • All content that you post is accurate;
    • You are at least 13 years old;
    • Use of the content you supply does not violate these Terms of Use and will not cause injury to any person or entity.
    You further agree that you may not submit any content:
    • That is known by you to be false, inaccurate or misleading;
    • That infringes any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
    • That violates any law, statute, ordinance or regulation (including, but not limited to, those governing, consumer protection, unfair competition, anti-discrimination or false advertising);
    • That is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased or offensive, unlawfully threatening or unlawfully harassing to any individual, partnership or corporation;
    • For which you were compensated or granted any consideration by any unapproved third party;
    • That includes any information that references other websites, addresses, email addresses, contact information or phone numbers;
    • That contains any computer viruses, worms or other potentially damaging computer programs or files.
    You agree to indemnify and hold Bookswagon (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party.


    For any content that you submit, you grant Bookswagon a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell, transfer, and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Additionally,  Bookswagon may transfer or share any personal information that you submit with its third-party service providers, including but not limited to Bazaarvoice, Inc. in accordance with  Privacy Policy


    All content that you submit may be used at Bookswagon's sole discretion. Bookswagon reserves the right to change, condense, withhold publication, remove or delete any content on Bookswagon's website that Bookswagon deems, in its sole discretion, to violate the content guidelines or any other provision of these Terms of Use.  Bookswagon does not guarantee that you will have any recourse through Bookswagon to edit or delete any content you have submitted. Ratings and written comments are generally posted within two to four business days. However, Bookswagon reserves the right to remove or to refuse to post any submission to the extent authorized by law. You acknowledge that you, not Bookswagon, are responsible for the contents of your submission. None of the content that you submit shall be subject to any obligation of confidence on the part of Bookswagon, its agents, subsidiaries, affiliates, partners or third party service providers (including but not limited to Bazaarvoice, Inc.)and their respective directors, officers and employees.

    Accept

    New Arrivals


    Inspired by your browsing history


    Your review has been submitted!

    You've already reviewed this product!