Bridging Traditions for a New Era in Personalized Natural Medicine: Volume 1 – Foundations and Mechanisms offers a comprehensive and authoritative exploration of the scientific principles underpinning the integration of natural products into the rapidly evolving field of personalized medicine. By integrating centuries of traditional medicinal knowledge with modern advances in molecular biology, pharmacogenomics, and precision medicine, this volume provides a rigorous evidence-based framework for understanding how natural compounds can be tailored to individual genetic, molecular, and clinical characteristics.
The book examines the evolution of personalized medicine, the role of natural products in modern drug discovery, pharmacogenomics, biomarker-guided therapies, and epigenetic regulation, before extending these concepts to precision approaches in oncology, autoimmune diseases, neuropharmacology, autism spectrum disorder, ADHD, and diabetes. Emphasis is placed on translating mechanistic insights into evidence-based therapeutic strategies and demonstrating the clinical potential of plant-derived bioactive compounds in precision healthcare.
Written by an international team of experts, each chapter combines current scientific evidence with emerging perspectives to support advanced learning, interdisciplinary research, and clinical innovation. An essential reference for postgraduate students, researchers, clinicians, and academics in pharmacology, pharmaceutical sciences, natural products, and precision medicine, this peer-reviewed volume provides an authoritative foundation for the future development of personalized natural therapeutics.
Key Features:
- Explores the origin, core concepts, and significance of personalized medicine, emphasizing its evolution in modern healthcare.
- Highlights how natural compounds contribute to drug development and their growing role in integrative, personalized treatment.
- Examines how genetic variations influence individual responses to natural products, shaping personalized phytotherapy.
- Discusses biomarkers used to predict, diagnose, and monitor therapy effectiveness when using natural products.
- Investigates how natural compounds can modulate gene expression without altering DNA, offering targeted treatment options.
Table of Contents:
List of Contributors. Chapter 1: Evolution and Principles of Personalized Medicine. Chapter 2: Natural Products in Contemporary Drug Discovery. Chapter 3: Pharmacogenomics, the Guiding Natural Product Therapies. Chapter 4: Biomarkers in Personalized Natural Medicine. Chapter 5: Epigenetic Mechanisms of Natural Compounds. Chapter 6: Natural Compounds in Precision Oncology. Chapter 7: Autoimmune Disorders: Tailored Phyto-therapeutic Approaches. Chapter 8: Neuropharmacology and Stress – Precision Herbal Interventions. Chapter 9: Personalized Natural Treatments for Autism and ADHD. Chapter 10: Tailored Natural Approaches to Diabetic Care. Index
About the Author :
Mahmoud A. H. Mostafa is Assistant Professor of Pharmacognosy and Medicinal Natural Products at Taibah University, Madinah, Saudi Arabia, and an Associate Professor at Al-Azhar University, Assiut, Egypt. He has deep expertise in natural product research and phytomedicine. His scholarly work bridges traditional ethnopharmacological knowledge with cutting-edge scientific methodologies, including artificial intelligence and bioinformatics, to advance precision therapeutic strategies. Dr Mostafa has authored numerous academic publications, led interdisciplinary research initiatives, and maintained active collaborations with institutions across the Arab region and internationally.
