Biophysics of Brain Imaging: Modeling Observations and Microscopic Phenomena

This book takes a multiscale overview and theoretical framework for all existing brain imaging modalities. It also presents technological development for data fusion and underlying biophysical models. The book also provides problems and exercises useful for undergraduate and graduate courses. Biophysics of Brain Imaging is broken up into 3 parts. Part 1: Modeling Observations and Microscopic Phenomena provides the physical and physiological foundation of all brain imaging modalities. Part 2 (Edited): Measuring and Modeling Emergent Mesoscopic Phenomena examines recording techniques and biophysical models used today to represent the mesoscale of the brain, the voxel. Part 3: Hypothesis Testing and Applications discusses methods to analyze brain imaging data and their applications to evaluate signatures in a variety of diseases, e.g., epilepsy, AD, and migraine. This book is intended for undergraduate and graduate level students in Computational Neuroscience, Medical Imaging, Electrophysiology, and Brain Data Analysis and Modeling courses. Figure slides are available to adopting professors.

Table of Contents:
Chapter 1. NMR-Based Techniques Chapter 2. Large-Scale Electrophysiological Techniques Chapter 3. Transmission-Emission Imaging Modalities Chapter 4. Functional Near-Infrared Spectroscopy (fNIRS) Chapter 5. The Neurons in Equilibrium Chapter 6. Neuronal Excitability Chapter 7. Inter-Neuronal Communication Chapter 8. Astrocyte Physiology Chapter 9. Astrocyte Functional Roles Chapter 10. The Vascular Response Appendix A. Introduction to Vector Calculus Appendix B. The Green Identities Appendix C. Magnetic LF – Isotropic Piecewise Homogeneous Conductor Appendix D. Special Functions

About the Author :
Jorge Riera obtained a B.S. in Physics at the University of Havana in 1988. During 1995–1998, he was “Junior Associate” of the International Centre for Theoretical Physics, Trieste (Italy), where he completed the required credits for a master’s degree in Biophysics. In 1999, he received the Ph.D. degree in Physics from the University of Havana. Part of his Ph.D. thesis was completed at the Cuban Neuroscience Center (CNC) and the Pitié-Salpêtriѐre Hospital in Paris. Dr. Riera’s postdoctoral term was first at the RIKEN Brain Science Institute (Japan) and, after, at NICHe, Tohoku University (Japan). In 2004, he was appointed Assistant Professor at the Tohoku University School of Engineering and promoted to Associate Professor of the Tohoku University School of Medicine in 2006. From 2006 to 2011, his research was funded by three Japanese agencies: Japan Society for the Promotion of Science, Telecommunications Advancement Organization of Japan, and Japan Science and Technology. In 2011, he joined Florida International University (FIU), first as Visiting Professor and later as Associate Professor in the Department of Biomedical Engineering. For the past twelve years he has directed the Neuronal Mass Dynamics (NMD) lab. At FIU, he has also been appointed by the Honor College, the Herbert Wertheim College of Medicine, and the STEM Transformation Institute. He is currently the Chair of the Biomedical Engineering Department. In 2024, he was elected fellow of the American Institute for Medical and Biological Engineering (AIMBE) for his outstanding contributions in advancing the technology of simultaneous functional magnetic resonance imaging and electroencephalography, from mouse to man.