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Signaling Mechanisms of Oxygen and Nitrogen Free Radicals

Signaling Mechanisms of Oxygen and Nitrogen Free Radicals


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About the Book

Once the existence of free radicals was proven, an avalanche of studies on free radical-mediated biological processes ensued. The study of reactive oxygen and nitrogen species (ROS and RNS) is center stage in biological free radical investigations. Written by a biochemist, Signaling Mechanisms of Oxygen and Nitrogen Free Radicals discusses the regu

Table of Contents:
Introduction. Formation of superoxide by major enzyme-catalyzed reactions. Formation of nitric oxide by no synthases. Formation of reactive oxygen and nitrogen species originated from superoxide and nitric oxide. Mechanisms of nucleophilic and one-electron transfer reactions of superoxide and NO. Signaling functions of superoxide and nitric oxide in heterolytic (nucleophilic) reactions. Mitochondrial disorders initiated by reactive oxygen and nitrogen species. Antagonistic signaling by superoxide and nitric oxide in pathological processes. Participation of superoxide and nitric oxide in apoptosis. Competition between superoxide and nitric oxide in aging and senescence.


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Product Details
  • ISBN-13: 9781040210901
  • Publisher: Taylor & Francis Ltd
  • Binding: Digital (delivered electronically)
  • ISBN-10: 1040210902
  • Publisher Date: 18 Jun 2009
  • Language: English


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