This two volume Second Edition describes the anatomical, physiological, pharmaceutical, and technological aspects of delivery routes, found in areas like:Oral Ocular Dermal and transdermal VaginalColonic Oral mucosal Nasal PulmonaryProviding insight and critical assessment of the many available and emerging modified release drug delivery systems fo
Table of Contents:
Introduction (The Modified Drug Release Landscape). The Modified Drug Release Landscape: Academic Viewpoint. The Modified Drug Release Landscape: Regulatory Viewpoint. The Modified Drug Release Landscape: Intellectual Property Viewpoint. Using Modified Release Formulations to Maintain and Develop Markets. Maintenance and Development of Markets. Approaches That Satisfy the Patients' Needs. Approaches That Satisfy the Doctors' Needs. Approaches That Satisfy the Innovators' Needs. The Need of the Investor. Oral. Introduction. Osmotic Systems. Qtrol. Qdis. Matrix Systems. SQZgel. Thiolated Polymers for CR. Oradur. IDD Technology. Chronotherapy Technology. Meltrex. Threeform. Floating Capsule. Cast Films for Oral Use. Monolithic and Composite Matrices for Modified Release Drug Delivery in Single or Multiple Drug Therapy. Dissocubes. Dose Sipping Technology. GIPET, GIRES. Micropump. Colonic and Rectal. Introduction. Test Systems for Colonic Devices. Enteric Coating for Colonic Delivery. Biopolymers and Colonic Delivery. Time-dependent Systems for Colonic Delivery. Pulsincap and Hydrophilic Sandwich (HS) Capsules. Egalet Technology. Ocular. Introduction. Ophthalmic Drug Delivery. Ocular Inserts. Intraocular Implants. Ion Exchange Resin Technology for Ophthalmic Applications. I-vation Sustained Release Intravitreal System. Oral Mucosal. Introduction. Oral-lyn (RapidMist Technology). Buccal Drug Delivery System. ORAVESCENT : A Novel Technology for the Transmucosal Delivery of Drugs. Medichew Technology Platform. DentiPatch. Medicated Chewing Gum. The BEMA Drug Delivery Technology. Oral Transmucosal System (OTS). Dermal and Transdermal. Introduction. ALZA Technologies (E-Trans, D-Trans, Macroflux, etc.). Metered Dose Transdermal Spray Technology. Microneedles for Drug Delivery. Transdermal Delivery. Transfersomes. Recent Advances in Wound Healing. Ultrasound in Transdermal Delivery. SLN and Lipopearls. Iontophoretic Delivery. Radiofrequency Technology. The PassPort Sys
About the Author :
MICHAEL J. RATHBONE is Director, Research and Development, and General Manager of InterAg, a Division of DEC International NZ Limited, Hamilton, New Zealand. Dr. Rathbone received his Ph.D. in Pharmaceutical Science from the University of Aston, Birmingham, England, and has innovated many novel modified-release drug delivery systems, several of which have been commercialized. Dr. Rathbone has written over 35 peer-reviewed articles, has licensed five US patents and has edited or co-edited three books and numerous special issues of journals.
JONATHAN HADGRAFT is Professor of Biophysical Chemistry, University of London, United Kingdom. Dr. Hadgraft received his D.Phil. in Chemistry and his D.Sc. in Medicine from the University of Oxford, United Kingdom. His major research interests are in the application of physical chemistry to drug delivery, with special reference to the skin. He has been elected to Fellowships of the Royal Society of Chemistry and the American Association of Pharmaceutical Scientists, and has contributed to over 500 publications. He has contributed numerous book chapters and has co-edited several books. He serves on a number of editorial boards of pharmaceutical science journals.
MICHAEL S. ROBERTS is Professor, School of Medicine, University of Queensland, Brisbane, Australia; Senior Principal Research Fellow, National Health and Research Council; Director Therapeutics Research Unit, Princess Alexandra Hospital, Queensland Australia; Adjunct Professor, University of Canberra, Australia; and Visiting Professor, University of Lyon, France. Dr. Roberts received his Ph.D. and D.Sc. from the University of Sydney, Australia, and his M.B.A. from the University of Queensland. Dr. Roberts has also written over 280 peer-reviewed articles, 36 chapters, and has edited or co-edited five books.
MAJELLA E. LANE is a lecturer in Pharmaceutics in the School of Pharmacy, University of London, United Kingdom. Sh
