In the ever-evolving field of upper gastrointestinal (UGI) and hepato-pancreatobiliary (HPB) surgery, staying informed about the pivotal research that shapes clinical practice is essential. 50 Landmark Papers every Upper GI and HPB Surgeon Should Know is a carefully curated collection of influential studies that have transformed decision-making in the management of complex conditions.
From groundbreaking insights into cancers of the stomach, liver, and pancreas to the management of bile duct injuries, hiatus hernia, and pharyngeal pouch, this book highlights the research that has redefined surgical approaches. It also delves into the historical significance of interdisciplinary collaboration, such as the creation of GI bleeding units, and includes key papers on endoscopic management and endoscopic retrograde cholangiopancreatography (ERCP), reflecting the evolving role of surgeons in these areas.
Organized into focused sections—gallbladder, liver, pancreas, stomach, bile duct, oesophagus, endoscopic treatment, obesity, and general topics—this book serves as a practical guide for surgeons and trainees alike. Each paper has been selected for its impact on clinical practice, offering a foundation for understanding the evidence that underpins modern surgical care.
Whether you are a seasoned surgeon or a trainee, this book will inspire you to explore the evidence, challenge established norms, and strive for excellence in the dynamic field of UGI and HPB surgery.
ABOUT THE EDITORS:
A H Sayed-Hassen BA, MBCHB, FRCS(Ed), FRACSDirector of Surgery Eastern Health, Melbourne
Senior Upper GI/HPB Surgeon, Eastern Health
Senior Lecturer, Monash University
Adrian Fox MBBS, FRACSHead of Upper GI/HPB, Eastern Health, Melbourne
Surgeon, St Vincent’s Hospital, Melbourne
Lecturer, Monash University
Table of Contents:
Section One: The Gallbladder
1 - Acute Cholecystitis: Early Versus Delayed Cholecystectomy, A Multi-centre Randomized Trial
2 - Laparoscopic cholecystectomy versus percutaneous catheter drainage for acute cholecystitis in high-risk patients (CHOCOLATE): multicentre randomised clinical trial
3 - Surgical outcomes of gallbladder cancer: the OMEGA retrospective, multicentre, international cohort study
Section Two: Liver
4 - Liver-directed surgery of neuroendocrine metastases: What is the optimal strategy?
5 - The Brisbane 2000 Terminology of Liver Anatomy and Resections
6 - Central venous pressure and liver resection: a systematic review and meta-analysis
7 - Systematic extrahepatic Glissonean pedicle isolation for anatomical liver resection based on Laennec’s capsule: proposal of a novel comprehensive surgical anatomy of the liver
8 - Liver transplantation for advanced hepatocellular carcinoma using poor tumour differentiation on biopsy as an exclusion criterion
9 - Portal Vein Embolization Before Right Hepatectomy; a prospective clinical trial10 - Arterial resection in Pancreatic cancer surgery: Effective after a learning curve
Section Three: Pancreas
10 - Arterial resection in Pancreatic cancer surgery: Effective after a learning curve
11 - Minimally invasive versus open distal pancreatectomy for resectable pancreatic cancer (DIPLOMA): an international randomised non-inferiority trial.
12 - Dunking pancreatico-jejunostomy versus duct-to-mucosa anastomosis.
13 - Endoscopic or surgical step-up approach for infected necrotising pancreatitis: a multicentre randomised trial
14 - Five-Year Outcomes of FOLFIRINOX vs Gemcitabine as Adjuvant Therapy for Pancreatic Cancer: A Randomized Clinical Trial
15 - International evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas.
16 - Short-term Outcomes After Spleen-preserving Minimally Invasive Distal Pancreatectomy With or Without Preservation of Splenic Vessels : A Pan-European Retrospective Study in High-volume Centres
17 - Neoadjuvant therapy or upfront surgery for resectable and borderline resectable pancreatic cancer: A meta-analysis of randomised controlled trials
18 - Roux-en-Y versus single loop reconstruction in pancreaticoduodenectomy: A systematic review and meta-analysis
19 - Should non-invasive diffuse main duct intraductal papillary mucinous neoplasms be treated with total pancreatectomy?
Section Four: Stomach
20 - Association between Helicobacter pylori Eradication and Gastric cancer incidence: A systematic review and Meta-analysis
21 - Clinical outcomes of a laparoscopic total vs a 270 posterior partial fundoplication in chronic gastro-oesophageal reflux disease.
22 - Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal Tumors
23 - Extended lymph-node dissection for gastric cancer.
24 - Laparoscopic vs Open Distal Gastrectomy for Locally Advanced Gastric Cancer 5-Year Outcomes of the KLASS-02 Randomized Clinical Trial
25 - Perioperative Durvalumab in Gastric and Gastroesophageal Junction Cancer
26 - Is Roux-en-Y or Billroth-II reconstruction the preferred choice for gastric cancer patients undergoing distal gastrectomy when Billroth I reconstruction is not applicable? A meta-analysis
Section Five: Bile Duct
27 - An analysis of the problem of biliary injury during laparoscopic cholecystectomy
28 - Preoperative Biliary Drainage for Cancer of the Head of the Pancreas
29 - Surgery for hilar cholangiocarcinoma: French experience in a collective survey of 552 extrahepatic bile duct cancers
30 - Tokyo Guidelines 2018: initial management of acute biliary infection and flowchart for acute cholangitis
Section Six: Oesophagus
31 - Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia
32 - Endoscopic versus surgical approach in the treatment of Zenker’s1 diverticulum: systematic review and meta-analysis.
33 - Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial
34 - Sutured versus Mesh-augmented Hiatus Hernia Repair. A systematic review and meta-analysis of randomized controlled trials
35 - Intraoperative pyloric drainage is unnecessary during esophagectomies: a meta-analysis and systematic review of randomized controlled trials
36 - Adjuvant Nivolumab in resected oesophageal or gastroesophageal junction cancer.
37 - Predictors of Anastomotic Leak After Esophagectomy: An Analysis of The Society of Thoracic Surgeons General Thoracic Database
38 - Robot-assisted Minimally Invasive Thoracolaparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy for Resectable Esophageal Cancer.
39 - Radiofrequency Ablation vs Endoscopic Surveillance for Patients with Barrett Esophagus and Low-Grade Dysplasia - A Randomized Clinical Trial
Section Seven: Endoscopic Treatment
40 - Early Treatment of Acute Biliary Pancreatitis by Endoscopic Papillotomy
41 - Endoscopic ultrasound- versus ERCP-guided primary drainage of inoperable malignant distal biliary obstruction: systematic review and meta-analysis of randomized controlled trials
42 - Indomethacin with or without prophylactic pancreatic stent placement to prevent pancreatitis after ERCP: a randomised non-inferiority trial
43 - Fully covered self-expandable metal stents (SEMS), partially covered SEMS and self-expandable plastic stents for the treatment of benign oesophageal ruptures and anastomotic leaks.
44 - Self-Expanding Metal Stents Versus Endoscopic Vacuum Therapy in Anastomotic Leak Treatment After Oncologic Gastroesophageal Surgery
Section Eight: Obesity
45 - Long-Term Outcomes of Laparoscopic Roux-en-Y Gastric Bypass vs Laparoscopic Sleeve Gastrectomy for Obesity: The SM-BOSS Randomized Clinical Trial
46 - Results from the Scandinavian Obesity Surgery Registry: A narrative review
Section Nine: General
47 - Advantages of enteral nutrition (EN) over parenteral nutrition (PN).
48 - Reduction in mortality from upper gastrointestinal haemorrhage
49 - Splenic Salvage: Is There a Role for Splenorrhaphy in the Management of Adult Splenic Trauma?
50 - Volume-Outcome Relationship in Surgery for Oesophageal malignancy: Systematic Review and Meta-analysis 2000-2011
About the Author :
A H Sayed-Hassen BA, MBChB, FRCS (Ed) FRACS is the Executive Director of Surgery at Eastern Health, Victoria. He qualified at Leeds University in 1985 and trained as a registrar in the Newcastle region in the late 1980s. Subsequently, he pursued further training in Upper GI and HPB surgery in Melbourne and a fellowship in Sydney, Australia. He has worked as a transplant surgeon (Austin), trauma surgeon (Alfred) as well as at Eastern Health (Upper GI/HPB) since 1997. He currently only works at Eastern Health and Epworth (private hospital). He is the Chair of Surgery
and also the Upper GI/HPB multidisciplinary meeting. He has had multiple roles at the College of Surgeons including the Chair of the Board in General Surgery, Treasurer of General Surgeons Australia (GSA) and has been the scientific convener for the Congress of the RACS in Singapore in 2014. He had also been the General Surgery convener for Hong Kong 2008 and multiple local conferences for GSA and for the pre-exam course of the General Surgery exam. He remains as chair of SEAM (since 2011) on the Australian Board of General Surgery, which is the educational arm of the Board. He has authored/edited most of the modules of SEAM, which is also assessed by the Board for the purposes of training in the early phases of SET.
Adrian Fox MBBS, FRACS is the Head of the Upper GI/HPB unit at Eastern health and also works at St Vincent’s Hospital in Melbourne. He qualified MBBS at the University of Melbourne in 1998 and did his registrar training at St Vincent’s Hospital. He did his fellowship training in HPB at St Vincent’s, Box Hill (eastern health), and spent 2 years in Toronto where he was exposed to HPB and transplant surgery. He has been heavily involved as supervisor of training for trainees and fellows in HPB surgery. He has authored several publications and is an active member of the board of ANZHPBA (Australian and New Zealand Board of HPB surgeons).
