About the Book
Those who responded to the COVID-19 pandemic have now had the opportunity to reflect on lessons learned, and in this science and data-rich book, those reflections are presented as a behind-the-scenes chronology of events and discoveries that occurred in COVID-19's wake. Offering a rubric for a future pandemic response, each chapter is written by experts, with their unique perspectives, experience, and learnings woven into visual roadmaps throughout the book. These roadmaps serve as a scaffolding upon which future healthcare leaders can build when creating, implementing and executing operational strategies in the face of future infectious disease outbreaks. Written for both lay and scientific audiences and featuring case studies which give clinical insight into the unique bond between COVID patients, their loved ones and their healthcare providers, this important book allows readers to leverage the knowledge of experts to improve the outcomes of future pandemics.
Table of Contents:
Introduction Tania Fernandez; 1. Early detection, response, and surveillance of the covid-19 pandemic crisis Enrique Rabellino, Alexandra Smith and Marta Cohen; 2. Immune system responses to SARS-CoV-2 Adolfo Firpo-Betancourt; 3. Clinical management: a roadmap for one nyc hospital's response to the covid-19 pandemic Barbara Barnett, Yvette Calderon, Erick Eiting, Young Lee, Lina Miyakawa, Waleed Javaid and Saralynne Brown; 4. Contribution of radx to the rapid development and commercialization of covid-19 diagnostic assays Steven Schachter, John Collins, Michael Dempsey, Laura Gibson, Matthew Robinson and Paul Tessier; 5. Coordination of resources for the deployment of covid-19 diagnostic assays Brian Walsh, Maren Downing, Mia Cirrincoine, Adam Samuta, Kevin Leite, Sam Dolphin, Emily Muth and Jose Valdesuso; 6. Quality and risk management processes for diagnostic assays during an emergency pandemic response Devon Campbell and Christie Johnson; 7. Development of assays to diagnose covid-19 Yuka Manabe and William Clarke; 8. Laboratory verification and clinical validation of covid-19 diagnostic assays Wilbur Lam, Leda Bassit, Anuradha Rao, Jennifer Frediani and Julie Sullivan; 9. Importance of timely sequencing, tracking and surveillance of emergent variants Anne Piantadosi, Jessica Lin, Morgan Greenleaf, Leda Bassit, Cassandra Wesselman and Yang Lu; 10. The RADx regulatory core and its role in covid-19 emergency use authorizations Erika Tyburski and Cathy Cambria; 11. Commercialization and market assessment of covid-19 assays Manuel Kingsley, Sunshine Moore and Heath Naquin; 12. Testing strategies to mitigate covid-19 disease spread Paul Tessier and Peko Hosoi; 13. A pandemic not just of infection but of inequality: the social impact of covid-19 Mara Aspinall and Liz Ruark; 14. Summary and path forward for future pandemics Wade Bolton and Steven Schachter.
About the Author :
Steven Schachter, MD is a Professor of Neurology at Harvard Medical School and Chief Academic Officer for CIMIT, Boston. As RADx Chief, Dr. Schachter led the design and implementation of the extramural aspects of the National Institutes of Health's Rapid Acceleration of Diagnostics (RADx) initiative to speed innovation in the development of technologies for COVID-19 testing. Wade Bolton, Ph.D. is Team Lead and Content Expert for VentureWell and works with the National Institutes of Health's Rapid Acceleration of Diagnostics (RADx) initiative to speed innovation in the development of technologies for COVID-19 testing. Previously, he was Divisional Vice President for Hematology Research and Development at Abbott Laboratories.
Review :
'I need to know what to do to protect people, my family, and my co-workers. I'm interested in all the areas this book covers.' Mirna DiPano, Ph.D., Vice President Regulatory and Clinical Affairs at NanoString Technologies, Inc.
'The concept addresses the significant gap that exists in the timely development of diagnostics that are both reliable and fit for purpose, a subject I am very interested in. I am very heartened that you have taken a multi-disciplinary approach to build a roadmap for the next pandemic and am curious to learn more.' Susie Braniff, Ph.D., Scientist, WHO, In Vitro Diagnostic Assessment Team
'OMG, this is going to be a landmark book. I cannot wait to read it.' Marcelle Abell-Rosen, M.D., Internal Medicine Physician
'An outstanding blend of science, real-world insights, and practical guidance that will be of great interest for both the lay audience and scientists. The diverse voices and visual roadmaps make this book a comprehensive and actionable guide, leaving readers better equipped to face future pandemics.' David A. Hafler, M.D., William S. and Lois Stiles Edgerly Professor of Neurology and Professor of Immunobiology,Chairman, Department of Neurology Yale School of Medicine; Neurologist-in-Chief Yale New Haven Hospital
'This book essentially reverse-engineers and then lays out the pathway that we were all involved in but we all failed to prepare for. This is a detailed, essential guide that provides a well-documented process for the managing our next pandemic.' J. Paul Robinson, Distinguished Professor of Cytometry, Professor of Biomedical Engineering, Professor of Computer and Information Management at Purdue University; Adjunct Professor of Microbiology & Immunology at West Lafayette Center for Medical Education, Indiana University School of Medicine; Director of Purdue University Cytometry Laboratories
'Future generations are certain to face public health challenges. Those of us who lived and worked through the COVID-19 pandemic have a duty to document and provide a roadmap to those who follow us and may need to urgently respond to similar challenges. The book, Accelerating Diagnostics in a Time of Crisis: The Response to COVID-19 and a Roadmap to Future Pandemics is an excellent resource for policymakers and those who are part of global public health responses.' Thomas N. Denny, M.Sc, M.Phil., Professor of Medicine, Chief Operating Officer, Duke Human Vaccine Institute; Director, Immunology and Virology Quality Assessment Center; Associate Dean for Duke Research and Discovery @ RTP
'After the COVID-19 crisis, the editors and contributors have put together a timely and pertinent publication that tackles the persistent issue of lessons learnt to prepare for future pandemics. This comprehensive work covers a range of crucial subjects, including early detection, immunology, surveillance, diagnostics, and the societal ramifications of pandemics.' Christopher Rudd, Christopher Rudd, Ph.D., DSc, FMedSci, FCAHS, FRSC, Professeur, Faculte de Medicine, Dept de microbiologie, infectiologie et immunologie, Director- Cell Signaling and Immunotherapy Section, Universite de Montreal
