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Elements of Evolutionary Genetics

Elements of Evolutionary Genetics


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About the Book

Evolutionary genetics is concerned with nature of the variability used in evolution, and the causes of evolutionary change. The methods of evolutionary genetics are critically important for the analysis and interpretation of the massive datasets on DNA sequence variation and evolution that are becoming available, as well for our understanding of evolution in general. This book shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data. The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure. The final two chapters demonstrate how the theory illuminates our understanding of the evolution of breeding systems, sex ratios and life histories, and some aspects of genome evolution.

Table of Contents:
1 Variability and its measurement 2 Basic selection theory and the maintenance of variation 3 Directional selection and adaptation 4 Migration, mutation and selection 5 The evolutionary effects of finite population size: basic theory 6 Molecular evolution and variation 7 Genetic effects of spatial structure 8 Multiple sites and loci 9 The evolution of breeding systems, sex ratios and life histories 10 Some Topics in Genome Evolution Mathematical and Statistical Appendix

About the Author :
Brian and Deborah Charlesworth obtained PhDs in genetics at Cambridge, and have subsequently worked at the Universities of Liverpool, Sussex, Chicago and Edinburgh, and are co-authors of a book about evolution for the general public. Brian is a Fellow of the Royal Society and Honorary Fellow of the American Academy of Arts and Sciences, and Deborah is a Fellow of the Royal Society. Both currently work on questions in population genetics, molecular evolution and genome evolution, and also on mating system evolution, including the evolution of sex chromosomes.

Review :
"The book by Charlesworth and Charlesworth provides an authoritative and accessible review of classical and modern population genetics. It can serve as a text for several graduate level courses and will be an invaluable reference to researchers in all areas of biology." -Montgomery Slatkin, University of California, Berkeley


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Product Details
  • ISBN-13: 9780981519425
  • Publisher: MacMillan Learning
  • Publisher Imprint: Roberts & Company Publishers
  • Height: 235 mm
  • No of Pages: 768
  • Width: 155 mm
  • ISBN-10: 0981519423
  • Publisher Date: 03 Feb 2010
  • Binding: Hardback
  • Language: English
  • Returnable: Y


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