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Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Neurology and clinical neurophysiology > Alzheimer's Disease: (No 11 Current problems in neurology)
Alzheimer's Disease: (No 11 Current problems in neurology)

Alzheimer's Disease: (No 11 Current problems in neurology)


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About the Book

Alzheimer's disease is an age-related progressive degenerative disease which constitutes the principal cause of dementia. It affects approximately 5-10% of the population over 65 years of age, rising to 20% of the population over 80 years of age. Improvements in health care in the developed world have resulted in an increasingly large elderly population and thus a growing number of Alzheimer's disease sufferers. The care of these patients presents a major and increasing human burden and drain on health care resources and thus the disease constitutes one of the major challenges to public health. Despite considerable knowledge about the clinical manifestations of Alzheimer's disease, its cause is at present unknown. This book outlines the clinical problems associated with Alzheimer's disease and seeks to provide a synthesis of knowledge of the major fields of research into the disease together with suggestions for future research. The topics covered include: neurotransmitter deficits, patterns of cerebral pathology, progression of the pathological changes, structure of neurofibrillary tangles and senile plaques, hippocampal pathology and memory impairment, animal models of amnesia and dementia, trace elements and the pathogenesis of the disease and the genetics of Alzheimer's disease. The book will be of interest to a wide variety of medical practitioners, research workers and students requiring accessible information about the current focus of research into Alzheimer's disease.

Table of Contents:
Alzheimer's disease - the clinical context, R.S.J.Briggs; transmitter deficits in Alzheimer's disease, R.F.Cowburn et al; patterns of cortical and sub-cortical pathology in Alzheimer's disease, M.M.Esiri; the pathogenesis and progression of the pathological changes of Alzheimer's disease, D.M.A.Mann; immunochemistry and composition of neurofibrillary tangles, D.P.Hue et al; the structure and protein chemistry of senile plaques and cerebrovascular amyloid, M.Landon and M.Kidd; trace elements and the pathogenesis of Alzheimer's disease, J.Candy et al; hippocampal pathology and memory impairment in Alzheimer's disease, D.C.Davies; disruption of the central cholinergic system in animals - models of dementia and amnesia, H.F.Baker and M.Ridley; the genetics of Alzheimer's disease, J.A.Hardy et al; future prospects for research into Alzheimer's disease, M.Rossor.


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Product Details
  • ISBN-13: 9780861961665
  • Publisher: John Libbey & Co
  • Publisher Imprint: John Libbey & Co Ltd
  • Height: 250 mm
  • Width: 170 mm
  • ISBN-10: 0861961668
  • Publisher Date: 01 Jan 1989
  • Binding: Hardback
  • Series Title: No 11 Current problems in neurology


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