Artificial Cells, Cell Engineering and Therapy

This authoritative reference provides a detailed study of the most up-to-date developments in artificial cells, cell engineering, and cell therapy. Broken down into four sections, the book covers the design, engineering, and uses of artificial cells and assesses the clinical relevance of artificial cells and cell engineering. Highlights include liposomes, nanocapsules, stem cell engineering for therapy, cell therapy approaches for spinal cord injury, treatment of cancer, insulin delivery, and pharmaceutical and industry to name just a few. This is a highly dynamic sector with growing interest in the use of engineered cells in controlled release of active drugs and other therapeutic agents.

Table of Contents:
THE ARTIFICIAL CELL Introduction to artificial cells: concept, history, design, current status and future S Prakash, J R Bhathena and H Chen, McGill University, Canada Polymeric hydrophilic polymers in targeted drug delivery K Poon, V Castellino and Y-L Cheng, University of Toronto, Canada The artificial cell design: liposomes G Barratt, Centre d'Etudes Pharmaceutiques, France The artificial cell design: nanoparticles W Yu and S Su, Celsion Corporation, USA CELL ENGINEERING The cutting edge: apoptosis and therapeutic opportunity C Griffin, D Gueorguieva, A McLachlan-Burgess, M Somayajulu-Nitu and S Pandey, University of Windsor, Canada Bone marrow stromal cells in myocardial regeneration and the role of cell signalling R Atoui, R C J Chiu and D Shm-Tim, McGill University, Canada Musculoskeletal tissue engineering with skeletal muscle-derived stem cells K A Corsi and J Huard, University of Pittsburgh, USA ARTIFICIAL CELLS FOR CELL THERAPY Artificial cell for oral delivery of live bacterial cells for therapy S Prakash, J Bhathena and A M Uurbanska, McGill University, Canada Artificial cells in liver disease V Dixit, University of California, USA Artificial cells as a novel approach to gene therapy M Potter, A Li, P Cirone, F Shen and P Chang, McMaster University, Canada Capillary devices for therapy J W Kawiak, L H Granicka, A Werynski and J M Wójcicki, Institute of Biocybernetics and Biomedical Engineering PAS and Medical Centre of Postgraduate Education, Poland THE CLINICAL RELEVANCE OF ARTIFICIAL CELLS AND CELL ENGINEERING Artificial cells in medicine: with emphasis on blood substitutes T M W Chang, McGill University, Canada Bone marrow stromal cells as 'universal donor cells' for myocardial regeneration therapy J Luo, R C-J Chiu and D Shum-Tim, McGill University, Canada Myocardial regeneration, tissue engineering and therapy R L kao, C E Ganote, D G Pennington and I W Browder, East Tennessee State University, USA Kidney diseases and potentials of artificial cells S Prakash, T Lim and W Ouyang, McGill University, Canada Engineered cells for treatment of diabetes S Efrat, Tel Aviv University, Israel Drug delivery system for active brain targeting X-G Mei, Beijing Institute of Pharmacology and Toxicology, China Artificial cells in enzyme therapy with emphasis on tyrosinase for melanoma in mice B Yu and T M S Chang, McGill University, Canada Stem cell and regenerative medicine: commercial and pharmaceutical implications L E Cruz and S P Azevedo, Cryopraxis Criobiologia Ltd, Brazil Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present therapy and therapeutic potential of cell-based therapy S-P Luh and S-Y Jiang, Tzu-Chi Medical University Hospital and R-Y Shyu, National Defence Medical Centre, Taiwan Inflammatory bowel diseases: current treatment strategies and potential for drug delivery using artificial cell microcapsules D Amre, University of Montreal, Canada and P D Amre and S Prakash, McGill University, Canada Carrier-mediated and artificial-cell targeted cancer drug delivery W C Zamboni, University of Pittsburgh, USA

About the Author :
McGill University, Montreal, Quebec, Canada