Practical Aspects of Ion Trap Mass Spectrometry, Volume III: Chemical, Environmental, and Biomedical Applications

By delivering concentrated information in three different volumes, the editors of the Practical Aspects of Ion Trap Mass Spectrometry mini-series present in-depth reviews on mainstream developments in each active and popular area. Contributing authors provide concise reports illustrating successful approaches to difficult analytical problems across the basic scientific disciplines.Volume three, Chemical, Environmental, and Biomedical Applications, presents a coherent picture of research and applications in the ion trapping field. It examines tandem mass spectrometry, the principal mode of ion trap operation, where one stage of mass selectivity follows another in the same region of space. This volume discusses the fundamentals of ion trap theory, design, and operation; practical ion trap technology; applications involving small molecules; and the environmental and biomedical applications.

Table of Contents:
Fundamentals
Ion Trap Theory, Design, and Operation, J.F.J. Todd
Introduction
Theory and Operating Principles of the Ion Trap Mass Spectrometer
Some Practical Improvements in Ion Trap Operation
Ion Isolation
Chemical Ionization
Extension of the Mass/Charge Range
High Resolution Mass Spectra with the Ion Trap
Tandem Mass Spectrometry
Applications
Conclusion
References
Ion Traps as Tandem Mass Spectrometers, R.E. March, R.J. Strife, and C.S. Creaser
Introduction
Instrumentation
Elements of Ion Trap Theory
Ion Formation and Isolation
The Ion Activation and/or Ion Reaction Period
Analytical Scan Rate
Practical Aspects of Tandem Mass Spectrometry
Tandem Mass Spectrometry Case Histories
Conclusion
Practical Aspects of Laser Desorption and Photodissociation
References
Review of Modern Ion Trap Research, J. Charles and G.L. Glish
Introduction
Ionization Techniques
Operation of the Ion Trap
Tandem Mass Spectrometry
Conclusion
References
Practical Ion Trap Technology
Practical Ion Trap Technology: GC/MS and GC/MS/MS, N.A. Yates, M.M. Booth, J.L. Stephenson, Jr., and R.A. Yost
Introduction
Instrumentation and Methods of Operation
GC/MS and GC/MS/MS Applications
Operational Principles for Ion Trap GC/MS
Advances in Ion Trap GC/MS and GC/MS/MS
Benchtop GC/MS/MS Instruments
Summary and Conclusion
References
Liquid Chromatography/Mass Spectrometry, B.L. Kleintop, D.M. Eades, J.A. Jones, and R.A. Yost
Introduction
Membrane Introduction
Thermospray
Particle Beam
Conclusions
References
Ion Spray Liquid Chromatography/Mass Spectrometry and Capillary Electrophoresis/Mass Spectrometry on a Modified Benchtop Ion Mass Spectrometer, A. Mordehai, H.K. Lim, and J.D. Henion
Introduction
Results and Discussion
Summary and Conclusions
Acknowledgments
References
Chemical Ionization in Ion Trap Mass Spectrometry, C.S. Creaser
Introduction
Principles of Chemical Ionization
Chemical Ionization in the Ion Trap
Selective Chemical Ionization Procedures
Applications
References
Applications Involving Small Molecules
Energetics and Collision-Induced Dissociation Efficiencies in the Quadrupole Ion Trap Mass Spectrometer, J.V. Johnson, C. Basic, R.E. Pedder, B.L. Kleintop, and R.A. Yost
Introduction
Ion Motion in a Quadrupole Ion Trap
Ion Activation in a QITMS
Calculations of Trapped Ion Energies
Experimental Determination of Trapped Ion Energies
Resonant Excitation in the QITMS: CID Energetics and Efficiencies
Conclusions
References
Ion Structure Studies in the Quadrupole Ion Trap, S. Catinella and P. Traldi
Introduction
Daughter Ion Spectroscopy by Ion Trap Mass Spectrometry (ITMS)
Applications
References
Atmospheric Glow Discharge/Ion Trap Mass Spectrometry, M.L. Langford and J.F.J. Todd
Introduction
Theoretical Features of the Glow Discharge Mechanism
Glow Discharge/Ion Trap Mass Spectrometers
References
Dynamically Programmed Scans, A.M. Franklin and J.F.J. Todd
Introduction
The "Scan" and "Exp" Programs
Dynamically Programmed Scanning Software
Processing of ITMSTM Data Files
Applications
Conclusions
References
Environmental and Biomedical Applications
Environmental Analyses, W.L. Budde
Introduction
Mass Spectrometer Performance Standards
The GC/Ion Trap Detector
Analytical Approaches in Environmental Analyses
Drinking Water Analyses in the United States
Membrane Mass Spectrometry
Field Applications
Volatile Air Pollutants
Less-Volatile Organic Analytes
Non-Volatile Compounds
References
Multi-Residue Pesticide Analysis, T. Cairns, K.S. Chiu, D. Navarro, and E. Siegmund
Driving Force for New Approach
Introduction
Experimental
Chemical Ionization of Pesticides
Analytical Approach to Pesticide Analysis
Conclusions
References
Electrospray/Ion Trap Mass Spectrometry: Applications to Trace Analysis, H.-L. Lin and R.D. Voyksner
Introduction
Optimization of Coupling of Electrospray to the ITMS
Application of Electrospray-ITMS to Environmental Analysis
Application of LC/Electrospray/ITMS for the Determination of Neuropeptides
Conclusions and Future Outlook
Acknowledgments
References


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About the Author :
March\, Raymond E.; Todd\, John F.J