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Liposome Technology, Second Edition, Volume I

Liposome Technology, Second Edition, Volume I


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About the Book

Liposome Technology, Second Edition, is an updated, expanded new edition of a classic volume in the field. It covers all aspects of liposome technology, including liposome preparation and analysis, drug entrapment, and techniques used for in vivo and in vitro evaluation of liposomes. Leading authorities have contributed 70 chapters to create what is destined to be the standard liposome technology book for the 1990s. Many of the chapters describe methodologies practiced in authors' laboratories and provide specific examples of how these methodologies are applied in specific circumstances. Liposome Technology, Second Edition will be an essential reference volume for academic and industrial researchers in pharmacology, pharmacy, medicine, biochemistry, and immunology. What's new in the 2nd Edition? The 2nd Edition covers significant developments in liposome technology that have occurred since the publication of the 1st Edition in 1982. These developments include the following: New preparative procedures Special approaches to accommodate the incorporation of certain drugs New targeting techniques Large scale production of liposomes, patents, and clinical trials

Table of Contents:
VOLUME I: LIPOSOME PREPARATION AND RELATED TECHNIQUES Lipid Properties as a Basis for Membrane Modelling and Rational Liposome Design (Gregor Cevc). Efficient Entrapment of Solutes in Microfluidized Small Dehydration-Rehydration Liposomes (Gregory Gregoriadis and Alexander T. Florence). Liposome Preparation Using High Pressure Homogenizers (Martin M. Brandl, Dieter Bachmann, Markus Drechsler, and Kurt H. Bauer). Preparation of Large Unilamellar Liposomes with High Entrapment Yield by Rotary Dialysis or Agarose Plug Diffusion (Susan Gould Fogerite and Raphael J. Mannino). A Mild Method for the Preparation of Very Large Unilamellar Liposomes (Jean R. Philippot and Jean P. Liautard). Preparation of MLV by the REV Method: Vesicle Structure and Optimum Solute Entrapment (Charles Pidgeon). Production and Size Control of Large Unilamellar Liposomes by Emulsification (Fumiyoshi Ishii). Reduction of Liposome Size and Preparation of Unilamellar Vesicles by Extrusion Techniques (Michael J. Hope, Rajiv Nayar, Lawrence D. Mayer, and Pieter R. Cullis). New Type of Lipid Vesicles: The Novasomes (D.F.H. Wallach and Jean R. Philippot). Non-Ionic Surfactant Vesicles: Preparation and Characterization (Alexander T. Florence). Preparation of Liposomes for Pulmonary Drug Delivery (Kevin M.G. Taylor and Stephen J. Farr). Stabilization of Liposomes During Spray-Drying (Helmut Hauser). Applications of Freezing and Thawing in Liposome Technology (Robert C. MacDonald and Ruby I. MacDonald). Preservation of Liposomes by Freeze Drying (John H. Crowe and Lois M. Crowe). Size Characterization of Liposomes (Peter Schurtenberger and Helmut Hauser). Size Characterization of Liposomes by HPLC (Anne Walter, Sylviane Lesieur, Robert Blumenthal, and Michel Ollivon). Partitioning of Liposomes in Aqueous Two-Phase Systems (Colin Tilcock, Judith Senior, Christina Delgado, Derek Fisher, and Gregory Gregoriadis). Density-Based Liposome Sizing by Glycerol Gradient Centrifugation (Erik Goormaghtigh and Gene A. Scarborough). Microelectrophoresis of Liposomes (Sai-Lung Law). Immobilization of Liposomes in Gel Beads (Per Lundahl, Qing Yang, Eva Greijer, and Maria Sandberg). Freeze-Fracture Electron Microscopy of Liposomes (Brigitte Sternberg). Studying Liposomes by X-Ray Scattering (M.F. Moody). Effects of Gamma Irradiation on the Liposomal Structure (Gianni Albertini and F. Rustichelli). Miniosmotic Pumps for Liposomal Drug Delivery (Sidney Lerman and Judith Megaw). Hydrodynamics of Liposomes and Their Multivalent Interaction with Surface Receptors (Anne L. Plant, Marsha Gray, Laurie Locascio-Brown, and William T. Yap). Analysis and Hydrolysis Kinetics of Phospholipids in Aqueous Liposome Dispersions (Mustafa Grit, Nicolaas J. Zuidam, and Daan J.A. Crommelin). The Preparation of Large Volumes of Sterile Liposomes for Clinical Applications (Reto A. Schwendener). A Large-Scale Method for the Preparation of Sterile and Non-Pyrogenic Liposomal Formulations of Defined Size Distributions for Clinical Use (Shimon Amselem, Alberto Gabizon, and Yechezkel Barenholz). Quality Control Assays in the Development and Clinical Use of Liposome-Based Formulations (Yechezkel Barenholz and Shimon Amselem).


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Product Details
  • ISBN-13: 9780849367076
  • Publisher: Taylor & Francis Inc
  • Publisher Imprint: CRC Press Inc
  • Edition: New edition
  • Language: English
  • No of Pages: 656
  • Weight: 1306 gr
  • ISBN-10: 0849367077
  • Publisher Date: 13 Oct 1992
  • Binding: Hardback
  • Height: 235 mm
  • No of Pages: 656
  • Returnable: N
  • Width: 156 mm


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