Physiological Basis of Aging and Geriatrics, Third Edition

Extensively revised and updated to reflect the current state of knowledge in the study of aging, the third edition of the bestselling Physiological Basis of Aging and Geriatrics provides an even more complete profile of the aging of individuals and populations. It includes aspects of demographic, comparative, and differential aging together with a discussion of the several theories of aging. It shows how body functions change with aging, describes how both genetic and environmental factors influence aging-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Divided into three main sections, the book first provides a broad and solid background in basic processes of biogerontology. Then it presents a survey of the aging of body systems, focusing on maintenance of optimal function and ability to adapt to environmental demands. Finally, it provides a synopsis of pharmacologic, nutritional, and physical exercise guidelines for preserving physical and mental health into old age. This book collects up-to-date information from internationally renowned experts in various biologic fields using physiology as the unifying concept. Illustrated with numerous tables and graphs, Physiological Basis of Aging and Geriatrics, Third Edition focuses on the established facts of physiological aging to provide an essential reference book for a wide spectrum of readers with different levels of biological and educational backgrounds.

Table of Contents:
GENERAL PERSPECTIVES Introduction: Aging as a Stage of Life, Common Terms Related to Aging, Methods Used to Study Aging, P.S. Timiras Demography of Aging, J.R. Wilmoth Comparative and Differential Aging, Epidemiology of Aging, P.S. Timiras Cell Senescence and Cell Death, J. Campisi Oxidants and Antioxidants in Aging, R.J. Mehlhorn Theories of Aging, J.R. Carey SYSTEMIC AND ORGANICMIC AGING Aging of the Nervous System: Structural and Biochemical Changes, P.S. Timiras Aging of the Nervous System: Functional Changes, P.S. Timiras Aging of the Sensory Systems, E. Meisami, C.B. Brown and H.F. Emerle Aging of the Adrenals and Pituitary, P.S. Timiras Aging of the Female Reproductive System, P.M. Wise Aging of the Ensemble Male Hypothalamo-Pituitary-Gonadal Axis, J.D. Veldhuis, A. Iranmanesh, M.L. Johnson and D. Keenan Aging of the Thyroid Gland and Basal Metabolism, P.S. Timiras The Endocrine Pancreas, and Carbohydrate Metabolism, P.S. Timiras Aging of the Immune System, L. Ginaldi and H. Sternberg Cardiovascular Alterations with Age, P.S. Timiras Lipids, Lipoproteins and Atherosclerosis, J.K. Bielicki and T.M. Forte Aging of the Pulmonary Respiration: Lungs, Martinis Aging of Hematopoiesis and Erythrocytes, and the Hematopoides, M. De Martinis and P.S. Timiras The Kidney, the Lower Urinary Tract, and Body Fluids, and the Prostate, M.L. Timiras and J. Leary Aging of the Gastrointestinal Tract and Liver, P.S. Timiras Aging of the Skeleton, Joints, and Muscles, P.S. Timiras The Skin and Connective Tissue, M.L. Timiras PREVENTION AND REHABILITATION Pharmacology and Drug Management in the Elderly, M.L. Timiras and J. Luxenberg An Agenda for Healthful Aging, F. Navazio and P.S. Timiras

Review :
"an excellent bookcurrent and useful to a broad spectrum of individuals with different levels of biological and educational backgroundsan excellent ready source of current information on aging and geriatrics for those working in these fields." - Denham Harman, M.D., Ph.D., University of Nebraska Medical Center, Omaha, Nebraska, USA "well-written and informative." - Roy J. Shephard, M.D., Ph.D., D.P.E., in Canadian Journal of Applied Physiology