Methods of Behavior Analysis in Neuroscience: (Frontiers in Neuroscience)

Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutical industry. The materials presented draw from the scholarly works of recognized experts in several fields of cognitive and behavioral neuroscience. Each contributor describes the most frequently used and most widely accepted version of the model, and each chapter includes: (1) a well-referenced introduction that covers the theory behind and the utility of the model; (2) a detailed and step-by-step methodology; and (3) an approach to the interpretation of the data presented. Many chapters also provide examples of actual experiments that use the method. This text eliminates the guesswork from the process of designing the methodology for many of the animal behavioral models that are used to study brain disorders, drug abuse, toxicology, and cognitive drug development. It will also significantly reduce the time spent assessing literature and developing models for studying animal subjects. Overall, Methods of Behavioral Analysis in Neuroscience is an invaluable reference source for the professional who seeks to comprehend the effects of disease on human cognition.

Table of Contents:
Choice of Animal Subjects in Behavioral Analysis, William J. Jackson The Behavioral Assessment of Sensorimotor Processes in the Mouse: Acoustic Startle, Locomotor Activity, RotaRod, and Beam Walking, Gerard B. Fox, Peter Curzon, and Michael W. Decker Fundamentals, Methodologies, and Uses of Taste Aversion Learning, T. Edward Orr, Paul A. Walters, and Ralph L. Elkins Drug Discrimination, Richard Young, John R. James, and John A. Rosecrans Intravenous Drug Self-Administration in Nonhuman Primates, Leonard L. Howell and Kristin M. Wilcox Assessing Attention in Rats, Philip J. Bushnell Assessment of Distractibility in Non-Human Primates Performing a Delayed Matching-to-Sample Task, Mark A. Prendergast Inhibitory Avoidance Behavior and Memory Assessment, John H. Graham and Jerry J. Buccafusco Spatial Navigational (Water Maze) Tasks, Alvin V. Terry, Jr. The Delayed Non-Match-to-Sample Radial Arm Maze Task: Application to Models of Alzheimer's Disease, Carl A. Boast, Thomas J. Walsh, and Adam C. Bartolomeo Use of the Radial-Arm Maze to Assess Learning and Memory in Rodents, Edward D. Levin An Operant Analysis of Fronto-Striatal Function in the Rat, Stephen B. Dunnett and Peter J. Brasted Use of Autoshaping with Non-Delayed and Delayed Reinforcement for Studying Effects upon Acquisition and Consolidation of Information, Sheldon B. Sparber Assessing Frontal Lobe Functions in Non-Human Primates, Jay S. Schneider Validation of a Behavioral Test Battery for Monkeys, Merle G. Paule Theoretical and Practical Considerations for the Evaluation of Learning and Memory in Mice, Robert J. Jaffard, Bruno Bontempi, and Frederique Menzaghi Index