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Home > Medicine & Health Science textbooks > Clinical and internal medicine > Diseases and disorders > Immunology > Interferon Therapy of Multiple Sclerosis
Interferon Therapy of Multiple Sclerosis

Interferon Therapy of Multiple Sclerosis


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About the Book

Presenting basic and clinical research on all forms of interferon (IFN) involvement in the management of multiple sclerosis (MS), this text details topics from IFN-receptor molecular interactions to synergy and interference with other agents such as cytotoxic drugs and chemotherapy. It features research findings on IFN beta-1a (Avonex) and IFN beta-1b (Betaseron), and covers the newly discovered IFN-tau - the potentially effective and less toxic type 1 IFN.

Table of Contents:
The Molecular Biology of Interferon-ß from Receptor Binding to Transmembrane Signaling, Lawrence M. Pfeffer and Stefan N. Constantinescu The Molecular Biology of Type I Interferons (Interferon- /ß) (Gene Activation, Promoters, Proteins Induced), Thomas Decker Pharmacokinetics of Interferon-ß and the Biological Markers It Induces, Patricia L. Witt Interferons and the Central Nervous System Glia, Timothy Vartanian Effects of Interferon on the Central Nervous System, Nachum Dafny, Bertha Prieto-Gomez, and Cruz Reyes-Vazquez Neuropsychological Effects of Interferon Therapy, Neil H. Pliskin, Anthony T. Reder, and Diane S. Goldstein The Effects of Interferon-ß on Cytokines and Immune Responses, Peter Rieckmann The Pathogenetic Role of Interferon- in Multiple Sclerosis, Gianvito Martino and Luigi M. E. Grimaldi The Effects of Interferons and Other Cytokines on Experimental Autoimmune Encephalomyelitis, Hubertine Heremans and Alfons Billiau Effects of Oral Administration of Type I Interferons on Experimental Autoimmune Encephalomyelitis, Staley A. Brod Interferon- in the Treatment of Multiple Sclerosis, Lorne F. Kastrukoff and Joel J.-F. Oger Recombinant Interferon- in the Treatment of Multiple Sclerosis: Effects on Exacerbation Rate, Magnetic Resonance Imaging of Lesion Activity, and Cytokines, Luca Durelli Inteferon ß-1a Treatment of Multiple Sclerosis, Robert M. Herndon Inteferon ß-1b (Betaseron) Treatment of Multiple Sclerosis, Robert L. Knobler Effects of Inteferon ß-1b on Multiple Sclerosis Lesions Evaluated by Magnetic Resonance Imaging and Other Magnetic Resonance Techniques, Robert A. Koopmans, David K. B. Li, Guo Jun Zhao, Elana Brief, Alex MacKay, Irene Vavasour, Ken Whittall, and Donald W. Paty Adverse Effects of Interferons, Richard Cirelli, Kathleen B. Herne, Monica L. McCrary, and Stephen K. Tyring Interferon-t: A Potential Treatment for Inflammatory Central Nervous System Disease, Jeanne M. Soos, Joel Schiffenbauer, Howard M. Johnson, and Carol H. Pontzer Clinical Trials of Multiple Sclerosis, Jeremy C. Hobart and Alan J. Thompson The Incidence and Clinical Significance of Antibodies to Interferon-a, Kjell Öberg and Rachel M. McKenna Quantitation and Characterization of Multiple Sclerosis Patient Antibodies to Interferon-ß, Eirik Nestaas, James G. Files, Jeffrey W. Nelson, and Erno Pungor, Jr.

Review :
" …an excellent reference for anyone interested in the basic mechanisms of action of the interferons and the clinical chapters provide a clear account of their role in the current management of patients with multiple sclerosis."-The Canadian Journal of Neurological Sciences, 1998


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Product Details
  • ISBN-13: 9780824797645
  • Publisher: Taylor & Francis Inc
  • Publisher Imprint: CRC Press Inc
  • Height: 229 mm
  • No of Pages: 570
  • Width: 152 mm
  • ISBN-10: 0824797647
  • Publisher Date: 28 Jan 1997
  • Binding: Hardback
  • Language: English
  • Weight: 918 gr


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