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Home > Science, Technology & Agriculture > Industrial chemistry and manufacturing technologies > Industrial chemistry and chemical engineering > Pharmaceutical chemistry and technology > Cell Culture Technology for Pharmaceutical and Cell-Based Therapies: (Biotechnology and Bioprocessing)
Cell Culture Technology for Pharmaceutical and Cell-Based Therapies: (Biotechnology and Bioprocessing)

Cell Culture Technology for Pharmaceutical and Cell-Based Therapies: (Biotechnology and Bioprocessing)


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About the Book

Edited by two of the most distinguished pioneers in genetic manipulation and bioprocess technology, this bestselling reference presents a comprehensive overview of current cell culture technology used in the pharmaceutical industry. Contributions from several leading researchers showcase the importance of gene discovery and genomic technology development in the production of biotechnology products, tissue engineering, and cell-based therapies. Offering detailed guidance, they cover the steps leading up to the creation of viable therapies including host cell selection, cloning and gene amplification, bioreactor design and operation, protein purification, optimization, scale-up, and facility design.



Table of Contents:
Preface. Cell Culture Technology: An Overview. Recombinant DNA Technology and Cell Line Development. Medium Development. Cell Metabolism. Protein Glycosylation. Cell Culture Bioreactors. Aeration, Mixing and Hydrodynamics in Bioreactors. Instrumentation and Process Control. Cell Culture Kinetics and Modeling. Fed-Batch Cultivation Of Mammalian Cells For Production Of Recombinant Proteins. Optimization of High Density Perfusion Bioreactors. Cell Separation And Product Capture. Downstream Processing. Formulation, Finishing, and Packaging. Validation Of Cell Culture Based Processes & Qualification Of Associated Equipment And Facility. Facility Design. Transient Expression of Proteins. Large-Scale Propagation of Insect Cells. Advances In Adult Stem Cell Culture. Ex Vivo Culture Of Hematopoietic And Mesenchymal Stem Cells For Tissue Engineering And Cell-Based Therapies.

Review :
"…The editors have brought together an outstanding group of experts from both private industry and academia….recommend[ed]." -Doody's Reviews


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Product Details
  • ISBN-13: 9780824753344
  • Publisher: Taylor & Francis Inc
  • Publisher Imprint: CRC Press Inc
  • Height: 254 mm
  • No of Pages: 786
  • Weight: 1620 gr
  • ISBN-10: 0824753348
  • Publisher Date: 30 Aug 2005
  • Binding: Hardback
  • Language: English
  • Series Title: Biotechnology and Bioprocessing
  • Width: 178 mm


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Cell Culture Technology for Pharmaceutical and Cell-Based Therapies: (Biotechnology and Bioprocessing)
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Cell Culture Technology for Pharmaceutical and Cell-Based Therapies: (Biotechnology and Bioprocessing)
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