Nitric Oxide and the Cell: Proliferation, Differentiation, and Death(Princeton Legacy Library)

Nitric oxide has proven to be a molecule with wide biological significance. It is involved in myriad actions which range from physiology to pathophysiology. One of the fundamental questions in relation to its biological relevance concerns the paradoxical nature of some of its actions. For example, there is a whole range of effects related to cytopr

Table of Contents:
PrefaceContributorsAbbreviations1Nitric oxide, mitochondria and cytotoxicity12Nitric oxide and its congeners in mitochondria: implications for apoptosis113Interactions between nitric oxide and cytochrome-c oxidase in turnover234Nitric oxide interactions with mitochondria and oxygen metabolism315Resistance factors for nitrosative and oxidative stress416S-Nitrosylation of thiol groups in haemoglobins from various species477Differential inhibitory action of nitric oxide and peroxynitrite on the R2 subunit of ribonucleotide reductase608Hydroxyguanidines as modifiers of cell proliferation and death: a possible role for nitric oxide719Control of cell growth by nitric oxide: the role of cGMP-dependent and -independent events occurring at various steps of growth factor-activated signalling processes8110Nitric oxide controls cell proliferation during Drosophila development9311Cytoprotective actions of nitric oxide in hepatic inflammation9912Activation of nuclear factor-kB and activator protein-1, and steady-state level of mRNA encoding tumour necrosis factor-[alpha] and inducible nitric oxide synthase in rat liver during different types of cell proliferation10713The mechanism of nitric oxide-induced apoptosis in the pancreatic [beta]-cell may involve cGMP and protein kinase G11314Normal and pathological expression of nitric oxide synthase in the central nervous system12315The role of astroglial cell-derived nitric oxide and prostanoids in death and repair mechanisms in the brain13516Role of nitric oxide and nerve growth factor in the mechanisms of neurotoxicity induced by the HIV-1 coat protein gp 120 in rat14517Mechanisms of neurotoxicity induced by the HIV-1 coat protein, gp 120, in human neuroblastoma cells in culture15518Nitric oxide mediates differentiation and survival of neuronal cells16919Neuromodulatory and neuroprotective actions of nitric oxide in the striatum17720Microdialysis study in vivo of the nitric oxide cGMP pathway in the hippocampus and cerebellum of adult and aged rats19121Mechanisms of neuronal apoptosis elicited by glutamate or nitric oxide donors21322Evidence that nitric oxide induces apoptotic cell death in the lateral geniculate nucleus of dark-reared rabbits21923Nitric oxide and prostaglandins in inflammation22724A further insight into the mechanism of lipoxygenase inhibition by nitric oxide23525The role of nitric oxide in T-cell functions24326CD95-induced calcium release and apoptosis are regulated by nitric oxide via a cGMP-dependent pathway in human [gamma][delta] T-lymphocytes24727Nitric oxide-initiated apoptotic cell death: activating and antagonistic signalling components25728Nitric oxide-induced apoptosis of RAW264.7 peritoneal macrophages: relationship between apoptosis and integrin expression profiles26929Nitric oxide, p53 and cancer27530The role of nitric oxide in Bacillus Calmette-Guerin-mediated anti-tumour effects in human bladder cancer28131Nitric oxide priming inhibits nitric oxide-mediated apoptosis289Subject index301