Pharmakon

An epic novel about family secrets and the consequences of ambition William Friedrich, an ambitious professor of psychology at Yale in 1952, has stumbled upon a drug that promises happinessaand that can make him a famous man. When his experiment goes awry, and a research subject commits murder, the consequences will haunt him and his family forever. Pharmakon is an epic novel, an invocation of the quest for bliss, for love, for family, and all of the betrayals that follow. We follow the Friedrichs from the well-ordered suburban life of postwar America through the chaos and freedom of the counterculture, into the drug-fueled, media-crazed eighties and beyond. In William Friedrich, Wittenborn has defined the archetypal American patriarch: a miracle worker and source of strength to everyone except those he loves the most. Pharmakon is also a layered, thoughtful search behind the veil of psychopharmacology as we know it todayaa tale not only of the consequences of research, but also of the complex personalities, appetites, and struggles that created it. Honest, insightful, and ruefully funny, Pharmakon captures formative moments of the twentieth century, the quirks of an American family, and will enthrall fans of the novels of John Irving.

Review :
?What's best about "Pharmakon," beyond the curiosity value of its unusual premise and atmosphere, is Mr. Wittenborn's colorful, affectionate evocation of a complex family story ?a smart, eccentric coming-of-age story.? ?"The New York Times" ?A smart, pharmaceutical pick-me-up.? ?"Seattle Times" ?Wittenborn is a smart stylist, equally adept at telling phrase and rich characterization.? ?"St. Petersburg Times" ?Pharmakon is a Greek word meaning both poison and cure. As the title of Dirk Wittenborn's novel, the word not only defines the early days of prescribed mood- altering drugs, but also the difficulty of truly understanding the triumphs and tragedies of a family's story. The novel is narrated by Zach Friedrich, youngest son of William Friedrich, who, just after World War II, develops a scale of happiness that allows clinicians to rate whether a person is becoming more or less happy (and more or less sane). He goes on to create, with a Yale coll aWhatas best about "Pharmakon," beyond the curiosity value of its unusual premise and atmosphere, is Mr. Wittenbornas colorful, affectionate evocation of a complex family story a]a smart, eccentric coming-of-age story.a a"The New York Times" aA smart, pharmaceutical pick-me-up.a a"Seattle Times" aWittenborn is a smart stylist, equally adept at telling phrase and rich characterization.a a"St. Petersburg Times" aPharmakon is a Greek word meaning both poison and cure. As the title of Dirk Wittenbornas novel, the word not only defines the early days of prescribed mood- altering drugs, but also the difficulty of truly understanding the triumphs and tragedies of a familyas story. The novel is narrated by Zach Friedrich, youngest son of William Friedrich, who, just after World War II, develops a scale of happiness that allows clinicians to rate whether a person is becoming more or less happy (and more or less sane). He goes on to create, with a Yale colleague, something he believes will be a cure for unhappiness, a pill derived from a New Guinea plant. When the trial ends in violence, the project is buried, William gets a job at Rutgers and Zach is born and grows up without knowing the secrets the family left behind. Despite the heavy subject matter, including murder, mental illness, family secrets and betrayal, "Pharmakon" is actually quite funnyanot surprising, given the authoras short stint on aSaturday Night Live.a Wittenborn is a witty and intelligent storyteller, and his own life story mirrors that of Zachas: heas a child born to a psycho-pharmacologist father who had a few disgruntled patients of his own. Readers will have fun trying to decidewhich parts of the story are autobiographical (was there really a girl named Sunshine and a gaggle of parrots in the mulberry tree?) and which parts come from the authoras imagination. Either way, this is the kind of book one imagines college professors read on their summer vacations: one that is at once smart, darkly funny, entertaining and informational, told with love and an eye toward the bigger issue of how families endure both the poisons and the curatives of everyday life.a a"Bookpage" aIt is 1951, and Will Friedrich, a young, ambitious, untenured Yale psychology professor is searching for a Big Idea, one that acould make the world a saner place.a Tragically, his big idea turns a geeky freshman genius into a murderer, and the specter of the event haunts Willas family for 50 years. "Pharmakon" is a family saga that takes Will, his wife, Nora, and their four children through the watershed moments of five turbulent decades of American history. But it is also a great deal more; by turns, a knowing and slightly jaundiced send-up of academia, a guided tour through some of the worst ideas of twentieth-century medicine and psychology, and an insightful portrait of a brilliant, decent, caring (albeit ambitious) man whose best efforts earn the approval of nearly everyone except those most important to him. "Pharmakon" is a big book in every way except page count. It is filled with vivid, nuanced characters and with ideas, and Wittenbornas engaging writing recalls Richard Russo.a -"Booklist" aIn "Pharmakon" Dirk Wittenborn has given us a fascinating portrait of a family living on the edge in the barely post-medieval age of 1950as psycho-pharmacology. Both victims andperpetrators, pioneers and innocents, the saga of the Freidrichs will stay with you long after the book has been read.a -Richard Price, author of "LUSH LIFE" "In "Pharmakon," Dirk Wittenborn has given us a haunting illustration of the Tolstoyan maxim that every unhappy family is unique in its unhappiness, though in fact no one who has ever been part of a family can fail to feel pangs of recognition as they follow the saga of the Friedrich family across three tumultuous generations. "PHARMAKON" is an ambitious and memorable novel." aJay McInerney, author of "Bright Lights, Big City" and "Brightness Falls" ""Pharmakon" is an old-fashioned novel about a modern subject--set in the past but completely relevant to where we are today. It might remind you of mid-period John Irving, but gentler. And just when you've settled into a groove the book takes surprising--sometimes shocking--turns. Beneath all the pain there's hope coursing through these pages, and in the end don't be surprised if you find yourself moved to tears." aBret Easton Ellis "A brilliant portrait of a young family of the 1950s, possessed of the particular qualities of post-war America -- optimism, prosperity and security -- and the inevitable loss of innocence as both country and family encounter the challenges of maturity. Dirk Wittenborn's provocative book is sharply observed; a subtle and wise fable of our time." --Susanna Moore, author of "In The Cut" aEerie, authentic, and always with heart, "Pharmakon" is a slow-burning triumph.a --Marisha Pessl, author of "Special Topics in Calamity Physics" aa]epically entertaining a]a a"Vogue" aA vivid sketch of an unhappy family inthe 1950s.a a"Chicago Tribune" aPharmakon is a Greek word meaning both poison and cure. As the title of Dirk Wittenbornas novel, the word not only defines the early days of prescribed mood- altering drugs, but also the difficulty of truly understanding the triumphs and tragedies of a familyas story. The novel is narrated by Zach Friedrich, youngest son of William Friedrich, who, just after World War II, develops a scale of happiness that allows clinicians to rate whether a person is becoming more or less happy (and more or less sane). He goes on to create, with a Yale colleague, something he believes will be a cure for unhappiness, a pill derived from a New Guinea plant. When the trial ends in violence, the project is buried, William gets a job at Rutgers and Zach is born and grows up without knowing the secrets the family left behind. Despite the heavy subject matter, including murder, mental illness, family secrets and betrayal, "Pharmakon" is actually quite funnyanot surprising, given the authoras short stint on aSaturday Night Live.a Wittenborn is a witty and intelligent storyteller, and his own life story mirrors that of Zachas: heas a child born to a psycho-pharmacologist father who had a few disgruntled patients of his own. Readers will have fun trying to decide which parts of the story are autobiographical (was there really a girl named Sunshine and a gaggle of parrots in the mulberry tree?) and which parts come from the authoras imagination. Either way, this is the kind of book one imagines college professors read on their summer vacations: one that is at once smart, darkly funny, entertaining and informational, told with love and an eye toward the bigger issue of how families endure both thepoisons and the curatives of everyday life.a a"Bookpage" aIt is 1951, and Will Friedrich, a young, ambitious, untenured Yale psychology professor is searching for a Big Idea, one that acould make the world a saner place.a Tragically, his big idea turns a geeky freshman genius into a murderer, and the specter of the event haunts Willas family for 50 years. "Pharmakon" is a family saga that takes Will, his wife, Nora, and their four children through the watershed moments of five turbulent decades of American history. But it is also a great deal more; by turns, a knowing and slightly jaundiced send-up of academia, a guided tour through some of the worst ideas of twentieth-century medicine and psychology, and an insightful portrait of a brilliant, decent, caring (albeit ambitious) man whose best efforts earn the approval of nearly everyone except those most important to him. "Pharmakon" is a big book in every way except page count. It is filled with vivid, nuanced characters and with ideas, and Wittenbornas engaging writing recalls Richard Russo.a -"Booklist" aIn "Pharmakon" Dirk Wittenborn has given us a fascinating portrait of a family living on the edge in the barely post-medieval age of 1950as psycho-pharmacology. Both victims and perpetrators, pioneers and innocents, the saga of the Freidrichs will stay with you long after the book has been read.a -Richard Price, author of "LUSH LIFE" "In "Pharmakon," Dirk Wittenborn has given us a haunting illustration of the Tolstoyan maxim that every unhappy family is unique in its unhappiness, though in fact no one who has ever been part of a family can fail to feel pangs of recognition as they follow the saga of theFriedrich family across three tumultuous generations. "PHARMAKON" is an ambitious and memorable novel." aJay McInerney, author of "Bright Lights, Big City" and "Brightness Falls" ""Pharmakon" is an old-fashioned novel about a modern subject--set in the past but completely relevant to where we are today. It might remind you of mid-period John Irving, but gentler. And just when you've settled into a groove the book takes surprising--sometimes shocking--turns. Beneath all the pain there's hope coursing through these pages, and in the end don't be surprised if you find yourself moved to tears." aBret Easton Ellis "A brilliant portrait of a young family of the 1950s, possessed of the particular qualities of post-war America -- optimism, prosperity and security -- and the inevitable loss of innocence as both country and family encounter the challenges of maturity. Dirk Wittenborn's provocative book is sharply observed; a subtle and wise fable of our time." --Susanna Moore, author of "In The Cut" aEerie, authentic, and always with heart, "Pharmakon" is a slow-burning triumph.a --Marisha Pessl, author of "Special Topics in Calamity Physics" aa]epically entertaining a]a a"Vogue" aA vivid sketch of an unhappy family in the 1950s.a a"Chicago Tribune" aIn "PHARMAKON" Dirk Wittenborn has given us a fascinating portrait of a family living on the edge in the barely post-medieval age of 1950as psychopharmacology. Both victims and perpetrators, pioneers and innocents, the saga of the Freidrichs will stay with you long after the book has been read.a --Richard Price, author of "LUSH LIFE" "In "PHARMAKON," Dirk Wittenborn has given us a haunting illustration of the Tolstoyan maxim that every unhappy family is unique in its unhappiness, though in fact no one who has ever been part of a family can fail to feel pangs of recognition as they follow the saga of the Friedrich family across three tumultuous generations. "PHARMAKON" is an ambitious and memorable novel." aJay McInerney, author of "BRIGHT LIGHTS, BIG CITY" and "BRIGHTNESS FALLS" ""PHARMAKON" is an old-fashioned novel about a modern subject--set in the past but completely relevant to where we are today. It might remind you of mid-period John Irving, but gentler. And just when you've settled into a groove the book takes surprising--sometimes shocking--turns. Beneath all the pain there's hope coursing through these pages, and in the end don't be surprised if you find yourself moved to tears." aBret Easton Ellis "A brilliant portrait of a young family of the 1950s, possessed of the particular qualities of post-war America -- optimism, prosperity and security -- and the inevitable loss of innocence as both country and family encounter the challenges of maturity. Dirk Wittenborn's provocative book is sharply observed; a subtle and wise fable of our time." --Susanna Moore, author of "In The Cut" aEerie, authentic, and always with heart, "Pharmakon" is aslow-burning triumph.a --Marisha Pessl, author of "Special Topics in Calamity Physics" "In PHARMAKON, Dirk Wittenborn has given us a haunting illustration of the Tolstoyan maxim that every unhappy family is unique in its unhappiness, though in fact no one who has ever been part of a family can fail to feel pangs of recognition as they follow the saga of the Friedrich family across three tumultuous generations.A PHARMAKON is an ambitious and memorable novel." aJay McInerney, author of BRIGHT LIGHTS, BIG CITY and BRIGHTNESS FALLS