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Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Pharmacology > Potassium Channel Modulators: Pharmacological, Molecular and Clinical Aspects(Frontiers in Pharmacology & Therapeutics)
Potassium Channel Modulators: Pharmacological, Molecular and Clinical Aspects(Frontiers in Pharmacology & Therapeutics)

Potassium Channel Modulators: Pharmacological, Molecular and Clinical Aspects(Frontiers in Pharmacology & Therapeutics)


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About the Book

Modulation of potassium channels plays a very important part in nerve cell function in the autonomic nervous system. Compounds are now in development which can open or close potassium channels and will have numerous therapeutic applications. The major areas of clinical relevance will be hypertension, asthma and irritable bladder syndrome. The book describes the pharmacology

Table of Contents:
Potassium channels in excitable cells: a synopsis; Potassium channel genes: genomic complexity, molecular properties, and differential expression; Cloning and pharmacology of voltage-gated potassium channels; G proteins and the modulation of potassium channels; High conductance calcium-activated potassium channels: molecular pharmacology, purification and regulation; The physiology and pharmacology of ATP-regulated potassium channels in insulin-secreting cells; Smooth muscle potassium channels: their electrophysiology and function; Potassium channels in the heart: physiological function and neurohormonal regulation; Potassium channels in mammalian neurones: their properties and prospects for pharmacological manipulation; Skeletal muscle potassium channels and their relevance to muscle disease; Naturally occurring potassium channel blockers; Potassium channel blockers: synthetic agents and their antiarrhythmic potential; Potassium channel activators: structure-activity relationships; Effects of potassium channel modulators on the cardiovascular system; The pharmacology of potassium channel modulators in airways smooth muscle: relevance to airways disease; Potassium channel modulators - urogenital pharmacology; Potassium channel openers: clinical aspects


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Product Details
  • ISBN-13: 9780632030446
  • Publisher: John Wiley and Sons Ltd
  • Publisher Imprint: Blackwell Science Ltd
  • Height: 234 mm
  • Sub Title: Pharmacological, Molecular and Clinical Aspects
  • Width: 156 mm
  • ISBN-10: 0632030445
  • Publisher Date: 27 Oct 1992
  • Binding: Hardback
  • Series Title: Frontiers in Pharmacology & Therapeutics
  • Weight: 1138 gr


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Potassium Channel Modulators: Pharmacological, Molecular and Clinical Aspects(Frontiers in Pharmacology & Therapeutics)
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Potassium Channel Modulators: Pharmacological, Molecular and Clinical Aspects(Frontiers in Pharmacology & Therapeutics)
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