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Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Neurology and clinical neurophysiology > The Cerebellum and its Disorders
The Cerebellum and its Disorders

The Cerebellum and its Disorders


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About the Book

Recent years have seen major advances in the understanding of motor and non-motor operations of the cerebellum, including its role in cognition, and important discoveries in the genetics of the cerebellar ataxias. This is a comprehensive text on the cerebellum and its disorders. It ranges from embryology and basic neuroanatomy to a thorough survey of the sporadic and hereditary disorders of the cerebellum. Models of cerebellar function and clinical-pathophysiological correlations are thoroughly covered, and there is an extensive and authoritative review of recent advances in the genetics of cerebellar diseases. The chapters are written by the leading international authorities on the cerebellum, including many of those who made fundamental discoveries in the field. The first comprehensive text on the cerebellum to be published for many years, this book will be essential reading for a wide range of basic and clinical neuroscientists, neurologists and others studying or treating cerebellar disorders.

Table of Contents:
Corticobasal degeneration Mario-Ubaldo Manto and Jean Jacquy; 13. Cerebellar stroke Serge Blecic and Julien Bogousslavsky; 14. Immune diseases Pierre Duquette; 15. Infectious diseases: radiology and treatment of cerebellar abscesses Jeffrey Weinberg and Mario-Ubaldo Manto; 16. Other infectious diseases Mario-Ubaldo Manto; 17. Cerebellar disorders in cancer Jerzy Hildebrand and Danielle Balériaux; 18. Posterior fossa trauma Matthias Maschke, Uwe Dietrich and Dagmar Timmann; 19. Thyroid hormone and cerebellar development Noriyuki Koibuchi; 20. Endocrine disorders: clinical aspects Mario-Ubaldo Manto and Henryk Zulewski; Part V. Toxic Agents: 21. Alcohol toxicity in the cerebellum: fundamental aspects Roberta Pentney; 22. Acohol toxicity in the cerebellum: clinical aspects Mario-Ubaldo Manto and Jean Jacquy; 23. Other cerebellotoxic agents Mario-Ubaldo Manto and Jean Jacquy; Part VI. Advances in Grafts: 24. Cerebellar grafts Lazaros C. Triarhou; Part VII. Neuropathology: 25. Neuropathology of inherited ataxias Arnulf H. Koeppen; Part VIII. Dominantly Inherited Progressive Ataxias: 26. Spinocerebellar ataxia type 1 Xi Lin, Harry T. Orr and Y. Zoghbi; 27. Spinocerebellar ataxias types 2 and 10 Stefan Pulst; 28. Spinocerebellar ataxia type 3 S. H. Subramony and Paraminder J. S. Vig; 29. Spinocerebellar ataxia type 4 Ying-Hui Fu and Louis J. Ptacek; 30. Spinocerebellar ataxia type 5 Christina L. Liquori, Lawrence J. Schut, H. Brent Clark, John W. Day and Laura P. W. Ranum; 31. Spinocerebellar ataxia type 6 Marina Frontali and Carla Jodice; 32. Autosomal dominant cerebellar ataxia with progressive pigmentary macular dystrophy Giovanni Stevanin, Anne-Sophie Lebre, Cecilia Zander, Géraldine Cancel, Alexandra Dürr and Alexis Brice; 33. Spinocerebellar ataxia type 8 Melinda L. Moseley, Lawrence J. Schut, John W. Day and Laura P. W. Ranum; 34. Dentatorubral-pallidoluysian atrophy Shoji Tsuji; 35. Molecular mechanisms of triplet repeat expansions in ataxias Robert D. Wells; Part IX. Recessive Ataxias: 36. Friedreich ataxia Massimo Pandolfo; 37. Early-onset inherited ataxias Guiseppe de Michele and Alessandro Filla; 38. Ataxia telangiectasia and variants Susan Perlman, Jacques-Olivier Bay, Nancy Uhrhammer and Richard A. Gatti; 39. Ataxia in mitochondrial disorders Massimo Zeviani, Carlo Antozzi, Mario Savoiardo and Enrico Bertini; 40. Episodic ataxias as ion channel disease Maria Cristina D'Adamo, Paulo Imbrici and Mauro Pessia; Index.

Review :
'This book … constitutes a major reference text for those primarily interested in the basic aspects of cerebellar functions and dysfunctions. it brings information in this domain up to date in a clear and lucid fashion.' Developmental Medicine & Child Neurology 'One of the most useful early chapters is the one by Bastian and Thach, who have written an excellent summary of the evidence - based on both recordings from single cells in animals and the effects of regional ablation or inactivation of the cerebellar cortex or nuclei - supporting a role for the cerebellum in behavior.' Mitchell Gickstein, University College London 'It is an extensive source of information about disorders, some common and many uncommon, that are relevant in a general neurologist's practice. … a valuable review of complex material not easily found in basic neuroscience textbooks or journals. I recommend this book to neurology residents for its basic science and clinical content. Practising neurologists will find it an excellent reference to use for assistance with the diagnosis and understanding of patients with cerebellar dysfunction.' Brian A. Anderson MD, University of Manitoba 'The book assembles an impressive list of authors, each of whom specializes in one or another aspects of cerebellar study.' The New England Journal of Medicine '… an excellent reference to use for assistance with the diagnosis and understanding of patients with cerebellar dysfunction.' Annals 'This is substantial, impressive, well referenced, exceedingly well illustrated and indeed beautiful internationally authored text … Even on first inspection, this scientific tour de force is a must for every department of neurology.' European Journal of Paediatric Neurology


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Product Details
  • ISBN-13: 9780521771566
  • Publisher: Cambridge University Press
  • Publisher Imprint: Cambridge University Press
  • Height: 283 mm
  • No of Pages: 612
  • Returnable: N
  • Spine Width: 43 mm
  • Width: 226 mm
  • ISBN-10: 0521771560
  • Publisher Date: 15 Nov 2001
  • Binding: Hardback
  • Language: English
  • Returnable: N
  • Returnable: N
  • Weight: 2420 gr


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