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Home > Medicine & Health Science textbooks > Clinical and internal medicine > Fever and Antipyresis: The Role of the Nervous System
Fever and Antipyresis: The Role of the Nervous System

Fever and Antipyresis: The Role of the Nervous System


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About the Book

This book provides a detailed overview of the function of the central nervous system (CNS) in fever and its role in combating fever (antipyresis). The volume opens with an introductory account of fever, its physiology and adaptive role, and explains the mechanisms of thermoregulation. It then provides information about bacterial pyrogens, "endogenous" pyrogenic cytokines, body temperature regulation and survival value of fever and its ubiquity, in order to enable readers to follow the CNS involvement. Finally, the author challenges some well established dogmas in this area and sets an agenda for future research. The book will help graduate students and researchers in neuroscience and other disciplines to understand the impact of their studies in the overall processes of fever. It will also be of benefit to pharmacologists studying antipyretics and the CNS function of these drugs. Academic clinicians will find this a more comprehensive overview of fever than other available texts.

Table of Contents:
Preface; 1. Fever – definition, usefulness, ubiquity; 2. Thermoregulation – an outline; 3. The nature of pyrogens, their origins and mode of release; 4. The loci of action of endogenous mediators of fever; 5. Beyond the loci of action of circulating pyrogens: mediators and mechanisms; 6. The role of the cerebral cortex, the limbic system, peripheral nervous system and spinal cord, and induced changes in intracranial pressure; 7. Antipyresis; 8. Febrile convulsions in children and a possible role for vasopressin; 9. A synthesis, predictions and speculation from my armchair; Appendix 1: Anatomical considerations; References; Index.

Review :
"Concise and comprehensive...Anyone who has ever pondered the topic of fever will find this book intriguing and informative. In this regard, the work has wide appeal. Graduate students in physiology--particularly if their area of research is fever, thermoregulation, or the hypothalamus--will consider this publication a gem." William C. Halliday, Annals RCPSC "This careful work encompasses over 30 years of work dedicated to the topic. It is a judicious account of a facet of medicine and neurology that interfaces with us all on both a personal and professional level." John Tibbles, Canadian Journal of Neurological Sciences "...this excellent and useful volume is rounded off with the author's synthesis of the material presented and what it means, along with his own provocative and stimulating speculations on where future research in this exciting field might lead." John T. Stitt, The Quarterly Review of Biology


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Product Details
  • ISBN-13: 9780521419246
  • Publisher: Cambridge University Press
  • Publisher Imprint: Cambridge University Press
  • Height: 236 mm
  • No of Pages: 200
  • Returnable: N
  • Spine Width: 15 mm
  • Weight: 517 gr
  • ISBN-10: 0521419247
  • Publisher Date: 18 May 1995
  • Binding: Hardback
  • Language: English
  • Returnable: N
  • Returnable: N
  • Sub Title: The Role of the Nervous System
  • Width: 156 mm


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