Multiple Sclerosis and CNS Inflammatory Disorders is a practical guide to effective care of patients with multiple sclerosis and other neuroimmunologic and CNS inflammatory disorders.
It provides the scientific basis of multiple sclerosis including etiology, epidemiology, and pathogenesis. It covers the diagnostic process, the course of the disease and prognosis, and the use of MRI in diagnosis and disease monitoring. Disease-modifying treatment algorithms for relapsing-remitting multiple sclerosis, switching therapy, and progressive multiple sclerosis treatment algorithms are all discussed in detail. It also addresses multiple sclerosis in childhood and pregnancy and includes assessment of alternative therapies.
This new addition to the Neurology in Practice series contains practical guidance and learning features:
• Algorithms and guidelines
• “Tips and Tricks” boxes on improving outcomes
• “Caution” warning boxes to avoiding problems
• “Science Revisited”—quick reminders of the basic science principles necessary for understanding
Multiple Sclerosis and CNS Inflammatory Disorders is an ideal reference for neurologists in practice and training.
Table of Contents:
Contributors vii
Series Foreword x
Preface xi
chapter 1 1
Etiology
Sonya U. Steele and Ellen M. Mowry
chapter 2 10
Immunopathogenesis of Multiple Sclerosis
Anne H. Cross and Laura Piccio
chapter 3 18
Diagnostic Process
Dalia Rotstein and Paul O’Connor
chapter 4 29
MRI in Diagnosis and Disease Monitoring
María I. Gaitán and Daniel S. Reich
chapter 5 45
Relapsing MS: Disease Staging and Therapeutic Algorithms
Mohsen Khoshnam and Mark Freedman
chapter 6 57
Progressive MS Treatment Algorithms
Megan H. Hyland and Jeffrey A. Cohen
chapter 7 67
Sex-Determined Issues in Multiple Sclerosis
Callene Momtazee and Barbara Giesser
chapter 8 77
Pediatric Multiple Sclerosis
Robert Thompson Stone and Brenda Banwell
chapter 9 91
Complementary and Alternative Medicine: Risks and Benefits
Allen C. Bowling
chapter 10 102
Symptomatic Management of MS
Jessica Robb, Lawrence M. Samkoff, and Andrew D. Goodman
chapter 11 114
Invisible Symptoms of MS: Fatigue, Depression, and Cognition
Leigh E. Charvet, Benzi Kluzer, and Lauren B. Krupp
chapter 12 122
Rehabilitation
Nesanet S. Mitiku, Alexius E. G. Sandoval, and George H. Kraft
chapter 13 134
Psychosocial Adaptation to Multiple Sclerosis
David J. Rintell
chapter 14 144
Transverse Myelitis and Acute Disseminated Encephalomyelitis
Benjamin M. Greenberg
chapter 15 153
Neuromyelitis Optica
Marcelo Matiello and Brian G. Weinshenker
chapter 16 163
Neurosarcoidosis
Thomas F. Scott
chapter 17 169
Lyme Neuroborreliosis
Erica Patrick and Eric Logigian
chapter 18 178
Neuro-Behçet Syndrome
Aksel Siva and Sabahattin Saip
Index 191
About the Author :
Lawrence M. Samkoff, MD, Associate Professor of Neurology at the School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY, USA
Andrew D. Goodman, MD, Professor of Neurology, Chief of the Neuroimmunology Unit, and Director of the Multiple Sclerosis Center at the School of Medicine and Dentistry, University of Rochester Medical Center , Rochester, NY, USA
