Veterinary Allergy

The current state of knowledge on this increasingly important subject is beautifully described in this, the first truly comprehensive text of allergic diseases affecting the major veterinary species. It will be an invaluable guide to students, clinicians and researchers alike. From the Foreword by Professor Richard Halliwell, MS, PhD, VetMB, MRCVS, Dip ACVD Veterinary Allergy is the first comprehensive, high quality reference dealing with all aspects of veterinary allergy in all species and all body systems involved with allergy. Providing solid breadth and excellent depth of coverage, it deals with the immunopathology of the various allergic conditions as well as with clinical presentation, diagnosis and treatment of veterinary allergic diseases. Key features: Broad species coverage, organised by sections on dogs, cats, horses, and other domestic species including large animals, birds and small mammals Provides details on diseases affecting the skin, respiratory tract and gut Contains practical information for clinicians on management of allergic diseases Includes fully-referenced high level detail suitable for specialists and researchers Focused on evidence-based medicine and science The editors have extensive experience and are respected as world-wide experts in the field Every chapter is written by an expert in that particular topic Anyone seeking information and references on any aspect of allergic conditions in any species should find this book helpful.  The book will be of interest to clinicians in first opinion practice, specialists in veterinary dermatology, gastroenterology, internal medicine, and immunology as well as specialists-in-training in those fields and veterinary students. The focus on underlying principles and practical clinical aspects is admirable. Immediately useful for practical utilization by practicing clinicians. Dr. Andrew Mackin BSc BVMS MVS DVSc FACVSc DSAM, Diplomate, American College of Veterinary Internal Medicine, Professor and Service Chief, Small Animal Internal Medicine, Dr. Hugh G. Ward Endowed Chair of Small Animal Veterinary Medicine, College of Veterinary Medicine, Mississippi State University, USA

Table of Contents:
Acknowledgments viii Contributors ix Foreword xiii Richard E.W. Halliwell Introduction: the immunological basis of allergic diseases xv Michael J. Day Part 1 – Canine Allergy (Editor: Chiara Noli) 1 Section 1 – Canine Atopic Dermatitis 3 1 Introduction: canine atopic dermatitis as an evolving, multifactorial disease 5 Douglas J. DeBoer 2 Canine immunoglobulin E 8 Bruce Hammerberg 3 The aberrant immune system in atopic dermatitis 16 Rosanna Marsella 4 Allergens and environmental influence 24 Pascal Prélaud 5 The genetics of canine atopic dermatitis 32 Tim Nuttall 6 Skin barrier and its role in the pathophysiology of atopic dermatitis 42 Koji Nishifuji 7 The role of bacterial agents in the pathogenesis of canine atopic dermatitis 51 David H. Lloyd 8 The role of fungal agents in atopic dermatitis 58 Ross Bond 9 Clinical signs of canine atopic dermatitis 65 Claude Favrot 10 Diagnosis of canine atopic dermatitis 70 Craig E. Griffin 11 Allergen avoidance 78 Daniel O. Morris 12 Allergen-specific immunotherapy 85 Ralf S. Mueller 13 Guidelines for symptomatic medical treatment of canine atopic dermatitis 90 Douglas J. DeBoer 14 Non-conventional treatments 96 Ralf S. Mueller Section 2 – Food Hypersensitivity 101 15 The pathogenesis of food allergy 103 Hilary A. Jackson 16 Cutaneous manifestations of food hypersensitivity 108 Didier N. Carlotti 17 Adverse reactions to food: a gastroenterologist’s perspective 115 Paola Gianella 18 Diagnostic workup of food hypersensitivity 119 Edmund J. Rosser Jr 19 Long-term management of food hypersensitivity in the dog 124 Nick J. Cave Section 3 – Flea Bite Allergy 133 20 Flea biology and ecology 135 Marie-Christine Cadiergues 21 The pathogenesis of flea bite allergy in dogs 140 Richard E.W. Halliwell 22 Clinical signs of flea allergy dermatitis in dogs 145 Emmanuel Bensignor 23 Diagnostic investigation of canine flea bite allergy 149 Dawn Logas 24 Implementing an effective flea control programme 152 Michael W. Dryden 25 Symptomatic relief for canine flea bite hypersensitivity 158 Dawn Logas Section 4 – Complicating Infections in Allergic Dogs 161 26 Complicating microbial skin infections in allergic dogs 163 Anette Loeffler 27 Otitis in the allergic dog 175 James O. Noxon Section 5 – Other Allergic Diseases in Dogs 183 28 Contact allergy 185 Rosanna Marsella 29 Venomous insect hypersensitivity 191 Mona J. Boord 30 Canine urticaria and angioedema 195 Peter Hill Part 2 – Feline Allergy (Editor: Aiden Foster) 201 Section 1 – Cutaneous Allergy in Cats 203 31 Pathogenesis—immunopathogenesis 205 Petra J. Roosje 32 Clinical presentations and specificity of feline manifestations of cutaneous allergies 211 Claude Favrot 33 Complications of cutaneous skin allergies (skin infections) 217 Laura Ordeix 34 Diagnostic investigation of the allergic feline 223 William E. Oldenhoff and Karen A. Moriello 35 Symptomatic treatments 228 Alison B. Diesel 36 Allergen-specific immunotherapy 234 Alison B. Diesel Section 2 – Feline Asthma 237 37 Feline asthma 239 Carol R. Reinero Section 3 – Flea Bite Allergy 247 38 Pathogenesis 249 Ross Bond 39 Clinical presentations 252 Dawn Logas 40 Diagnostic workup 255 Dawn Logas 41 Therapy 259 Marie-Christine Cadiergues Section 4 – Mosquito Bite Allergy 265 42 Mosquito bite 267 Masahiko Nagata Part 3 – Equine Allergy (Editor: Wayne Rosenkrantz) 271 Section 1 – Culicoides Hypersensitivity and Other Insect Allergies 273 43 Pathogenesis and epidemiology of Culicoides hypersensitivity 275 Bettina Wagner 44 Equine immunoglobulin E 279 Eliane Marti and Eman Hamza 45 Clinical manifestations of Culicoides hypersensitivity 287 Janet D. Littlewood 46 Culicoides hypersensitivity: diagnosis 291 Kerstin Bergvall 47 Culicoides hypersensitivity: therapy 297 Anthony A. Yu 48 Other biting insect allergies 307 Gwendolen Lorch Section 2 – Atopic Disease in Horses—Atopic Dermatitis and Food Hypersensitivity 327 49 Equine atopic dermatitis: pathogenesis 329 Valerie A. Fadok 50 Clinical aspects of equine atopic disease 334 Wayne Rosenkrantz and Stephen White 51 Equine urticaria 338 Valerie A. Fadok 52 Equine headshaking syndrome 344 Harold C. Schott II and Annette D. Petersen 53 Diagnostic workup of equine atopic disease 353 Wayne Rosenkrantz and Stephen White 54 Equine atopic disease symptomatic therapy and allergen-specific immunotherapy 360 Wayne Rosenkrantz and Stephen White Section 3 – Recurrent Airway Obstruction and Inflammatory Airway Disease 371 55 Recurrent airway obstruction and inflammatory airway disease 373 Vinzenz Gerber Section 4 – Contact and Other Allergic Diseases 385 56 Equine allergic contact dermatitis 387 Chris Reeder and Joya Griffin Part 4 – Allergy in Other Domestic Species (Editor: Aiden Foster) 395 57 Immunopathogenesis of allergic skin disease in livestock 397 Adri van den Broek 58 Psoroptes ovis 402 Adri van den Broek and Stewart T.G. Burgess 59 Allergic diseases of livestock species 411 Aiden P. Foster 60 Allergies in birds 422 Claudia S. Nett-Mettler 61 Allergic diseases in other pets (rodents, rabbits, and ferrets) 428 Ian Sayers Index 433

About the Author :
Chiara Noli, DVM, DipECVD Dr. Chiara Noli graduated in veterinary medicine from the University of Milan, Italy, in 1990. After a residency at the University of Utrecht, Holland, she obtained the European Diploma in Veterinary Dermatology in 1996. Since then she works as referral dermatologist and dermatopathologist in Northen Italy. Dr. Noli is Past President and Founder Member of the Italian Society of Veterinary Dermatology, Past President of the European Society of Veterinary Dermatology and has been Board Member of the International Society of Veterinary Dermatopathology and of the World Association for Veterinary Dermatology. Dr. Noli lectures extensively in national and international meetings, is author of more than 100 articles in Italian and international journals, of nine book chapters and of three veterinary dermatology textbooks. Aiden Foster PhD, DipACVD, MRCVS Aiden Foster worked for 20 years dealing with companion animal dermatology cases in referral and first opinion practices. He trained in veterinary dermatology at the College of Veterinary Medicine, University of Wisconsin, USA and taught veterinary dermatology at the University of Bristol veterinary school. He has been the editor of the BSAVA Manual of Small Animal Dermatology 2nd edition and was an editor of the proceedings of the 5th World Congress of Veterinary Dermatology published as Advances in Veterinary Dermatology volume 5. He is a past president of the European Society of Veterinary Dermatology and has been editor-in-chief of the Wiley-Blackwell journal Veterinary Dermatology since 2006. He works for the Animal Health and Veterinary Laboratories Agency which deals with diseases of livestock.  Wayne Rosenkrantz DVM, DipACVD Wayne Rosenkrantz graduated from the University of California Davis in 1982. He obtained Diplomate status with the American College of Veterinary Dermatology (ACVD) in 1986. Dr. Rosenkrantz is a co-owner of all of the Animal Dermatology Clinics in the United States, and continues to actively see cases. He is a past-president of the American College of Veterinary Dermatology (ACVD) executive board and has been on past and current organizing committees for the World Congress of Veterinary Dermatology (WCVD) and a current member of the World Association for Veterinary Dermatology (WAVD). He has served on the examination committees for the ACVD as well as the Australian Board examinations. Dr. Rosenkrantz lectures and teaches extensively, and has published numerous articles and book chapters on small animal and equine dermatology. He is very active in clinical drug trials, research studies and consults with several dermatological therapeutic companies. He also received the ACVD Award for Excellence for outstanding contributions in veterinary dermatology in 2007.

Review :
“This is an excellent update on the new discoveries in the field of immunology that have increased the understanding of the pathogenesis of allergic diseases.”  (Doody’s, 16 January 2015) “These features make this a useful reference for veterinarians with an interest in veterinary allergy.”  (Journal of the American Veterinary Medical Association, 15 September 2014) “I enjoyed this book, learned and was reminded of a lot, and I recommend it as essential reading for all veterinary dermatologists and residents. The book is good value and a good choice for practices with a library. It is available in print and electronically.”  (Veterinary Record, 29 November 2014) “A must for anyone wishing to understand and manage accordingly those itchy, diarrhoeic or suffocating animals.”  (Vets Today, 1 August 2014) “In this context, one sees the importance of books of this nature. As is the case with other specialized titles in veterinary medicine, I hope that Veterinary Allergy has come to stay and we will have successive revised, expanded and updated editions, helping to keep us informed and to manage our allergic patients properly.”(Veterinary Dermatology, 5 July 2014) “From clinical presentation and treatment to allergic diseases, science and references for specialists and researchers, and chapters written by experts, this provides a powerful and highly recommended veterinary exploration that any clinician or vet student must have in their reference collections.”  (Midwest Book Review, 1 June 2014)