Epilepsy and the Interictal State: Co-morbidities and Quality of Life

Epilepsy care traditionally focuses on seizures, yet for most epilepsy sufferers, other interictal factors such as mood, cognitive abilities, and treatment adverse effects most influence how they feel and function day to day. Epilepsy and the Interictal State is a practical and comprehensive text that covers quality of life issues, cognition and therapy, adverse effects of epilepsy treatments, mood state and psychiatric co-morbidity and general health aspects of epilepsy. Each chapter employs a standard structure providing background, epidemiology, pathophysiology, etiology, diagnosis, treatment, prognosis and further practical advice. From an international team of expert editors and contributors, Epilepsy and the Interictal State is a valuable resource for specialist epileptologists and neurologists, as well as for neurosurgeons, neurology nurses, psychiatrists, family physicians and general practitioners.

Table of Contents:
List of contributors ix Foreword xiii Section I: Quality of life and the interictal state in epilepsy 1 Quality of life in epilepsy: the key importance of the interictal state 3 David M. Ficker 2 Comorbidities in epilepsy: range and impact 7 J. Layne Moore and John O. Elliott 3 Epilepsy, comorbidities, and consequences: implications for understanding and combating stigma 15 Rosemarie Kobau, Colleen K. DiIorio, Nancy J. Thompson, Yvan A. Bamps, and Erik K. St. Louis Section II: Cognition and epilepsy 4 Causes and types of cognitive domain impairments in epilepsy 29 Impairment of consciousness in epilepsy 31 Luigi Maccotta, Clemente Vega, and R. Edward Hogan Ictal cognitive impairments due to nonconvulsive status epilepticus 38 Elizabeth Waterhouse Memory and dysexecutive impairments in epilepsy 45 Erik K. St. Louis and Ashley M. Enke Attention deficit/hyperactivity disorder, disordered attention, and epilepsy 63 David W. Dunn and William G. Kronenberger Behavioral and developmental disorders in epilepsy 68 Michael Smith and Esmeralda L. Park 5 Cognitive effects of epilepsy therapies 74 Beth A. Leeman and Kimford J. Meador 6 Autism and epilepsy 88 Vladimýr Komárek 7 Cognitive rehabilitation strategies in epilepsy 94 Cher Stephenson and Robert D. Jones Section III: Adverse effects of epilepsy therapies 8 Adverse effects in epilepsy: recognition, measurement, and taxonomy 103 Frank G. Gilliam, Laura S. Snavely, and Piero Perucca 9 Clinically important antiepileptic drug interactions and their influence on adverse effects in epilepsy 110 Frank M.C. Besag and Philip N. Patsalos 10 Minimizing the adverse effects of epilepsy therapies: principles and practice 120 Erik K. St. Louis 11 Idiosyncratic adverse side effects of antiepileptic drugs: risk, prevention, and counselling 127 Mary L. Zupanc and Lily H. Tran 12 Antiepileptic drug therapy and fetal development 136 Frank J.E. Vajda Section IV: Mood state, psychiatric comorbidity, and epilepsy 13 Mood state, anxiety, and psychosis in epilepsy 147 Michael Salzberg 14 The contribution of sleep and anxiety disorders to quality of life in people with epilepsy 159 Dee Snape, Ann Jacoby, and Gus Baker 15 Epilepsy and personality 171 Christopher Turnbull, Simon Jones, Sophia J. Adams, and Dennis Velakoulis 16 Psychogenic attacks and epilepsy 183 Bláthnaid McCoy and Selim R. Benbadis Section V: General health and epilepsy 17 Obesity and epilepsy 195 Sandra J. Petty and Alison M. Pack 18 Epilepsy in the elderly: vascular disease, the aging brain, and selection of appropriate therapies 203 Katherine H. Noe and Joseph I. Sirven 19 Balance disorders and falls in epilepsy 216 Sandra J. Petty, Keith D. Hill, and John D. Wark 20 Bone health in epilepsy 224 Sandra J. Petty, and John D. Wark 21 Sleep and epilepsy 230 Irakli Kaolani and Erik K. St. Louis 22 Use of complementary and alternative medicine in epilepsy 241 Dana Ekstein and Steven C. Schachter 23 Epilepsy and alcohol and substance abuse 252 Ekrem Kutluay and Jonathan C. Edwards 24 Driving, employment, and related issues in epilepsy 258 Kristine Ziemba and Joe Drazkowski Index 267

About the Author :
Erik K. St Louis, Department of Neurology, Mayo Clinic, Rochester, MN, USA David M. Ficker, Department of Neurology, University of Cincinnati, Cincinnati, OH, USA Terence J. O’Brien, Departments of Medicine and Neurology, The Royal Melbourne Hospital, The University of Melbourne, Parkville, Vic, Australia