Coordination and Transport Properties of Macrocyclic Compounds in Solution: Volume 76(Volume 76 Studies in Physical and Theoretical Chemistry)

This book covers the fundamental physical principles of the selective complexation, extraction, and transport of ions and molecules by macrocyclic compounds - both natural and synthetic. It also treats the use of these compounds for the extraction and transport of substrates in chemical and biological systems. Included are solution kinetic and thermodynamic properties of the complexes, along with relevant experimental methods, complemented by solution and solid-state structures. General and specific methods for the synthesis of macro(poly)cyclic specialised ligands are described. The book is useful as additional reading for undergraduate courses in chemistry (e.g. inorganic complexation chemistry, analytical chemistry, solution kinetics, synthesis) and biochemistry (ion transport/membrane phenomena); for graduate students in chemistry and biochemistry; for research workers in macrocyclic chemistry and biophysical chemistry; and for industrial laboratories involved in metal ion extraction and recovery.

Table of Contents:
Introduction. Classification of Ligands. Selective Complexation. Ion Solvation. Properties of Solvents. Thermodynamics of Complex Formation. Introduction. Nomenclature of Ligands and Complexes. Experimental Techniques. Thermodynamic Parameters of Complexation. Factors Determining the Stabilities and Selectivities of Complexes. The Macrocyclic and the Cryptate Effect. Functionalised Macrocycles. Medium and Counterion Effects. Kinetics and Mechanism of Complex Formation. Introduction. Kinetic Methods. Results. Reaction Mechanisms. Solvent Extraction of Metal Ions. Introduction. Extraction Equilibria. Results. Conclusions. Carrier Mediated Ion Transport Across Membranes. Introduction. Biological Membranes. Phospholipid Bilayers. Experimental Methods for Ion Transport. Results and Discussion. Structural Studies. Introduction. Valinomycin Antibiotics. Carboxylic Ionophores. Crown Ethers. Pendant-Arm Macrocycles. Rigid Macrocycles and Macrobicycles. Synthesis of Macrocyclic Ligands. Introduction. Aza-Macrocycles. Crown Ethers. Cryptands. Spherands. Pendant-Arm Macrocycles. Miscellaneous. References. Index.

Review :
...an essential book for workers in this important field...clearly written, well illustrated, and well produced... Faraday Transactions ...should be in the library of each practitioner of the macrocyclic art. It is a volume that nicely fulfills its somewhat specialized mission but offers a little extra that makes it a valuable addition to any library. Journal of the American Chemical Society ...a major contribution to the field and should certainly be in the personal library of anyone interested in macrocyclic chemistry. Coordination Chemistry Reviews