Handbook of Neuropsychology, 2nd Edition: Volume 7 The Frontal Lobes(Volume 7 Handbook of Neuropsychology)

Animal research has contributed greatly to our understanding of the special capability of the frontal lobes to respond to a variety of input from "lower order" sensory and posterior association cortex and this and other observations are reported in this volume. Findings that functions dependent on the frontal lobes emerge late in ontogeny and appear to decline early in normal aging are reviewed and their implications for neuropsychology are discussed. In this volume the concept of working memory is discussed in relationship to both functional neuroimaging and patient studies. Gross distinctions in the functioning of the prefrontal cortex have divided it topographically into dorsolateral and ventromedial sectors. Chapters highlighting the role of the dorsolateral and ventromedial sectors from both neuroimaging and lesion perspectives are also included. Computational modeling has taken center-stage in cognitive neuroscience and its usefulness in testing different theoretical stances about the role of the frontal lobes in information processing is presented.

Table of Contents:
Preface. List of contributors. 1. Anatomic basis of functional specialization in prefrontal cortices in primates (H. Barbas, H.T. Ghashghaei, N.L. Rempel-Clower, D. Xiao). 2. The prefrontal cortex: conjunction and cognition (E.K. Miller, W.F. Asaad). 3. Working memory: Findings from neuroimaging and patient studies (E.E. Smith, C. Marshuetz, A. Geva). 4. Age, cognition and emotion (L. Phillips, S. McPherson, S. Della Sala). 5. The frontal lobes and frontal-subcortical circuits in neuropsychiatric disorders (S. McPherson, J.L. Cummings). 6. The somatic marker hypothesis and decision-making (A. Bechara, D. Tranel, A.R. Damasio). 7. Neuropsychological consequences of dysfunction in human dorosolateral prefrontal cortex (S.W. Anderson, D. Tranel). 8. The human prefrontal cortex has evolved to represent components of structured event complexes (J. Grafman). 9. The processing of temporal information in the frontal lobe (P. Nichelli). 10. Neural network models of prefrontal cortex and cognitive control (J.D. Cohen). Subject index.

About the Author :
François Boller, M.D., Ph.D. has been co-Series Editor of the Handbook of Clinical Neurology since 2002. He.is a board-certified neurologist currently Professor of Neurology at the George Washington University Medical School (GW) in Washington, DC. He was born in Switzerland and educated in Italy where he obtained a Medical Degree at the University of Pisa. After specializing in Neurology at the University of Milan, Dr. Boller spent several years at the Boston VA and Boston University Medical School, including a fellowship under the direction of Dr. Norman Geschwind. He obtained a Ph.D. in Experimental Psychology from Case Western Reserve University in Cleveland, Ohio where he was in charge of Neuroscience teaching at the Medical School and was nominated Teacher of the Year. In 1983, Dr. Boller became Professor of Neurology and Psychiatry at the University of Pittsburgh where he founded and directed one of the first NIH funded Alzheimer Disease Research Centers in the country. In 1989, he was put in charge of a Paris-based INSERM Unit dedicated to the neuropsychology and neurobiology of cerebral aging. He returned to the United States and joined the NIH in 2005, before coming to GW in July 2014. Dr. Boller’s initial area of interest was aphasia and related disorders; he later became primarily interested in cognitive disorders and dementia with emphasis on the correlates of cognitive disorders with pathology, neurophysiology and imaging. He was one of the first to study the relation between Parkinson and Alzheimer disease, two processes that were thought to be unrelated. His current area of interest is Alzheimer’s disease and related disorders with emphasis on the early and late stages of the disease. He is also interested in the history of Neurosciences and is Past President of the International Society for the History of Neurosciences. He was the founding Editor-in-Chief of the European Journal of Neurology, the official Journal of the European Federation of Neurological Societies (now European Academy of Neurology). He is a Fellow of the American Academy of Neurology and a member of the American Neurological Association. In addition, he has chaired Committees within the International Neuropsychological Society, the International Neuropsychology Symposium, and the World Federation of Neurology (WFN). He has authored over 200 papers and books including the Handbook of Neuropsychology (Elsevier). Dr. Grafman has been the director of Brain Injury Research at the Shirley Ryan AbilityLab ((SRALab)formally known as the Rehabilitation Institute of Chicago) since 2012 and is on faculty at Northwestern University’s Feinberg School of Medicine in the Departments of Physical Medicine and Rehabilitation, Neurology, Psychiatry and Behavioral Sciences, and the Cognitive Neurology and Alzheimer’s Disease Center as well as the Department of Psychology in the Weinberg College of Arts and Sciences. Before joining the SRALab, Dr. Grafman was briefly director of Traumatic Brain Injury Research at the Kessler Foundation in West Orange New Jersey. Prior to that appointment in 2011, Dr. Grafman was Chief of the Cognitive Neuroscience Section at the National Institute of Neurological Disorders and Stroke in Bethesda, Maryland for many years. His investigation of brain function and behavior contributes to advances in medicine, rehabilitation, and psychology, and informs ethics, law, philosophy, and health policy. His study of the human prefrontal cortex and cognitive neuroplasticity incorporates neuroimaging and genetics, an approach that is expanding our knowledge of the functions of the human frontal lobes, as well as the effects of neurological disorders that impair frontal lobe brain function.