Surface Characterization of Biomaterials: Symposium Proceedings(Progress in Biomedical Engineering)

Surface Characterization of Biomaterials is the first book to define the scope of contemporary research in this area by presenting articles from almost all the groups worldwide who are utilizing both new and traditional methods to explore the surfaces of biomaterials. The book contains introductory, tutorial articles on important methods, perspective articles clarifying why these methods are important to biomaterials science, and sixteen research articles illustrating how these tools are being used by most of the leaders in this field. The techniques featured include ESCA, static SIMS, contact angle methods, scanning electron stimulated desorption microscopy, Fourier transform infrared methods, and transmission electron microscopy. The classes of materials described include polymers, ceramics and metals. Surface modification of many of these materials is discussed. The biological problems addressed include blood compatibility, cell adhesion, osteointegration, and protein adsorption. The book will be welcomed by researchers and manufacturers interested in biomaterials. Experts in the field will find an overview of contemporary research.

Table of Contents:
I. Perspectives. Biomaterials from a surface science perspective (B. Kasemo, J. Lausmaa). Surface characterization of biomaterials: How finely can we resolve surface structure? (B.D. Ratner). II. Tutorial Articles. Introduction to X-ray photoelectron spectroscopy (R.W. Paynter). The determination of the surface tensions of solid films (E. Sacher). Static secondary ion mass spectrometry: a new technique for characterization of biomedical polymer surfaces (D.G. Castner, B.D. Ratner). III. Techniques for Characterization of Biomolecules at Interfaces. Scanning electron stimulated desorption microscopy of biological and organic surfaces (J.H. Abrams, H.F. Dylla). Surface characterization of protein-coated polymer materials (D.R. Absolom). Weak and strong lipid-protein interactions characterized by the monolayer technique (F. Lamarche et al.). Waste microbial biomass as a de-emulsifying agent (R.P. Lyng, N. Kosaric). IV. Surface Characterization of Biomaterial Interfaces. Electron and vibrational spectroscopic studies of the surfaces of biocompatible materials (J.A. Gardella Jr. et al.). Preparation, surface spectroscopic and electron microscopic characterization of titanium implant materials (J. Lausmaa et al.). Surface spectroscopy of calcium phosphate ceramic and titanium implant materials (P. Ducheyne, K.E. Healy). XPS and related studies of a plasma modified contact lens co-polymer (D.W. Fakes et al.). V. Cell Interactions with Characterized Surfaces. The effect of surface topography on cell migration and adhesion (D.M. Brunette). The importance and measurement of surface charge species in cell behavior at the biomaterial interface (J.E. Davies). Erythrocyte adhesion to polymer surfaces: physicochemical and hydrodynamic factors (D.R. Absolom). VI. Surface Characterization of Block Copolymers of Biomedical Interest. Surface analysis of polyether and polysiloxane soft segment polyurethanes (K.G. Tingey et al.). Surface characteristics and antithrombogenicity of segmented copolymers with crystalline/amorphous microdomains (N. Yui et al.). Surface and bulk morphology of polyurethanes by electron microscopies (S.L. Goodman et al.). Surface degradation of biomedical polyurethanes (R.E. Marchant et al.). ESCA and static SIMS studies of polyurethane surfaces (B.D. Ratner et al.). Author Index. Subject Index.