Practical Guide to Diagnosing and Treating Ocular Tumors

Practical Guide to Diagnosing and Treating Ocular Tumors provides practical guidance on the diagnosis and management of ocular tumors. This comprehensive guide highlights the strengths, limitations, and applications of all imaging modalities in ocular oncology. It not only discusses new treatments in ocular oncology (including belzupacap sarotalocan and darovasertib for uveal melanoma, mTOR inhibitors for retinal astrocytic hamartomas in patients with ocular involvement of tuberous sclerosis complex, and belzutifan for retinal hemangioblastomas in patients with Von Hippel Lindau disease), but also offers a comprehensive and practical review of the techniques, complications, and applications of well-established treatments. Ophthalmologists and ocular oncologists will find this to be a practical guide to diagnosing and treating surface and intraocular tumors using a novel approach that will instruct readers on how to utilize and interpret multimodal imaging correctly to diagnose ocular tumors. Readers will gain an understanding of the risks and benefits of different treatment modalities and the most appropriate use scenario in each tumor type.

Table of Contents:
SECTION I – Diagnostic Modalities 1. Slit Lamp Photography 2. Fundus photography 3. Fundus Autofluorescence and Near-Infrared Imaging 4. Optical coherence tomography (OCT) Anterior Segment OCT Swept-source OCT OCT angiography 5. Fluorescein Angiography and Indocyanine Green Angiography 6. Ultrasonography A-scan and B-scan ultrasonography Ultrasound biomicroscopy (UBM) Doppler ultrasonography 7. Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) 8. Diagnostic Interventions Fine-needle Aspiration Biopsy (FNAB) Vitrector-assisted retinal and choroidal biopsies Diagnostic vitrectomy Liquid biopsy SECTION II – Treatment Modalities 9. Local Therapies 10. Plaque brachytherapy 11. Teletherapy External Beam Proton Beam Stereotactic Radiotherapy 12. Topical and Intralesional Chemotherapy 13. Systemic Chemotherapy 14. Immunotherapy and Targeted Therapy 15. Intra-arterial Chemotherapy 16. Intravitreal Chemotherapy 17. Surgery of the Conjunctiva 18. Intraocular surgery 19. Enucleation and Exenteration

About the Author :
Maura Di Nicola is an Assistant Professor of Ophthalmology at the Bascom Palmer Eye Institute, University of Miami Miller School of Medicine in Miami, FL. She specializes in ocular oncology, uveitis, and medical retina. She spent two years as a research associate on the ocular oncology service at the University of Cincinnati and completed fellowships in ocular oncology at Wills Eye Hospital and University of Cincinnati. She subsequently completed a fellowship in uveitis and medical retina at University of Illinois in Chicago. She grew up in Italy, where she attended San Raffaele University for medical school and University of Milan for ophthalmology residency. Her research interests include diagnosis and treatment of adult and pediatric tumors, as well as ocular inflammatory diseases, with a focus on multimodal imaging. Basil K. Williams Jr. is a board-certified ophthalmologist and an Associate Professor of Ophthalmology at the Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine in Miami, FL. He is the department’s Vice Chair for Diversity, Equity and Inclusion and specializes in ocular oncology and vitreoretinal surgery and diseases. He completed his residency, vitreoretinal fellowship and chief residency at the Bascom Palmer Eye Institute followed by an ocular oncology fellowship at Wills Eye Hospital. Prior to joining faculty in Miami, he was the Director of Ocular Oncology and held the Mary Knight Asbury Endowed Chair at the University of Cincinnati. He was born in St. George’s Grenada and grew up in the Bronx, NY. His research interests pertain to health care disparities, adult and pediatric surface and intraocular tumors, and vitreoretinal surgical topics.