Quick Guide to Diabetes Mellitus

Quick Guide to Diabetes Mellitus, Second Edition provides essential knowledge on the pathophysiology, etiology, epidemiology, diagnosis, laboratory evaluation, and basic clinical management of diabetes and its complications targeted to laboratory scientists and technicians. Eleven percent of the U.S. population have been diagnosed with diabetes mellitus, and laboratory scientists play an essential role in the diagnosis, monitoring, and management of this disease. This reference presents an easy-to-read question-and-answer format that will provide fundamental knowledge and aid in commonly encountered clinical challenges. This updated release includes new information on genetic and environmental risk factors for type 1 and 2 diabetes, pediatric glucose targets per American Diabetes Association Standards, type 2 diabetes management sections, including treatment guidelines and information on glucagon-like peptide-1 receptor agonists and gastric bypass surgery.

Table of Contents:
1. Pathophysiology 2. Historical Context 3. Insulin Secretion and Action 4. Etiology 5. Type 1 Diabetes 6. Genetic Risk Factors 7. Environmental Risk Factors 8. Stages of Type 1 Diabetes 9. Type 2 Diabetes 10. Genetic Risk Factors 11. Environmental Risk Factors 12. Other Diabetes 13. Monogenic diabetes 14. Type 3c diabetes 15. Others 16. Epidemiology 17. Type 1 Diabetes 18. Type 2 Diabetes 19. Diagnosis & Ongoing Evaluation 20. Diagnostic criteria in adults & children 21. Diagnostic criteria in pregnancy 22. Testing considerations 23. Timing of screening 24. Glycated hemoglobin 25. Oral glucose tolerance testing 26. Fasting & random plasma glucose 27. Measuring Glucose in the Lab 28. Type 1 versus type 2 diabetes 29. Other tests 30. Diabetes Emergencies 31. Diabetic ketoacidosis 32. Hyperglycemic hyperosmolar state 33. Complications 34. Acute signs, symptoms, & complications 35. Chronic complications a. Microvascular disease b. Macrovascular disease c. Neuropathy d. Others 36. Clinical Management 37. Treatment goals 38. Self-monitoring of blood glucose 39. Capillary blood glucose 40. Continuous glucose monitors 41. Medical management 42. Type 1 diabetes 43. Type 2 diabetes 44. Associated risk factors 45. Conclusion

About the Author :
Dr. Winter is a professor of pathology, immunology, and laboratory medicine; pediatrics; and molecular genetics and microbiology at the University of Florida in Gainesville. He is principal investigator for the National Institutes of Health-funded Type 1 Diabetes TrialNet Islet Cell Autoantibody Core Laboratory and Islet Autoantibody Standardization Program. Dr. Winter directs the endocrine autoantibody laboratory that at the University of Florida, has given numerous presentations and has published extensively on behalf of the AACC. A multiple-time winner of the AACC outstanding speaker award, Dr. Winter has served on several AACC annual meeting organizing committees. He is a fellow of the College of American Pathologists and the National Academy of Clinical Biochemistry, which he served as a member of the board of directors. He has contributed more than 200 articles, chapters, and abstracts. Brittany Bruggeman, MD, is a board-certified pediatrician and pediatric endocrinologist and Diplomat, for the American Board of Pediatrics. Dr. Bruggeman received numerous scholarly awards. Most recently she received the 2020 Douglas J. Barrett, MD Academic Fellowship Award that recognizes pediatric clinicians or researchers for displaying the highest qualities in research, teaching and patient care. Dr. Bruggeman is a member of many professional organizations including the American Academy of Pediatrics, the American Diabetes Association and the Type 1 Diabetes TrialNet, an international network of endocrinologists at the forefront of Type 1 diabetes Laura Jacobsen, MD, is an assistant professor and pediatric endocrinologist who joined the University of Florida faculty in 2018 in the department of pediatrics. She completed her pediatric residency training at the University of North Carolina in Chapel Hill, which was followed by a pediatric endocrinology fellowship at the UF Health Shands Children’s Hospital in Gainesville, Florida. During her fellowship, Dr. Jacobsen was recognized for her excellence in medical student teaching, and she received the Henry A. Kokomoor Outstanding Fellowship Award. Dr. Jacobsen provides clinical care for children with endocrine disorders and diabetes. She performs clinical and translational research in the field of Type 1 diabetes to better understand what causes Type 1 diabetes and ways to halt or prevent it. Dr. Timothy P. Foster is a pediatric endocrinologist in Gainesville, Florida. He received his medical degree from Florida Atlantic University Charles E. Schmidt College of Medicine and has been in practice between 6-10 years. Pediatric endocrinologists treat disorders of the hormone-secreting glands that regulate countless body functions. These ailments include diabetes, thyroid ailments, metabolic and nutritional disorders and pituitary diseases. He has published