Essential Guide to Neurodegenerative Disorders
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Essential Guide to Neurodegenerative Disorders: Mechanistic, Diagnostic and Therapeutic Advances

Essential Guide to Neurodegenerative Disorders: Mechanistic, Diagnostic and Therapeutic Advances


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About the Book

Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich' s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches.

Table of Contents:
Part-I: Mechanism of cell death in neurodegeneration 1. Pathways in AD 2. Shared signalling pathways in Alzheimer’s and metabolic disease 3. Abeta pathology in AD and its potential to seed and propagate 4. Single-cell approaches to identify shared and distinct signatures across neurodegenerative diseases 5. Modelling of neurodegenerative disease using brain organoids 6. The structural basis of protein assembly into amyloid filaments in neurodegenerative disease-Benjamin 7. Blood brain barrier in neurodegenerative disorders 8. Protein misfolding in neurodegeneration 9. Neuroinflammation and neurodegeneration 10. Gut-Brain Axis in neurodegeneration 11. Modelling Neural Circuits in Parkinson’s Disease 12. Neuropathology of Parkinsonism in Alzheimer’s Disease 13. Huntington Disease updates 14. Neuroinflammation in neurodegeneration Part-II: Gene and gene products in neurodegeneration 15. Big data and neurodegeneration disorders 16. Genomics and PD 17. RNA Binding Proteins and the Genesis of Neurodegenerative Diseases-Ahmed Moustafa, Egypt 18. Molecular Genetics of Huntington’s Disease 19. neuronopathic LSDs: opportunities and challenges 20. Nutrigenomics and PD 21. Genes and MS: updates 22. Genetic mapping and big data in ALS Part-III: Present and future diagnostic approaches of neurodegenerative disorders 23. Biomarkers in AD 24. Biomarkers of PD 25. HMGB complex in PD diagnosis 26. Psychological assessment of PD patients Part-IV: Present and future therapeutics of neurodegenerative disorders 27. Pharmacotherapy of neurodegenerative disorders: challenges and hopes 28. Advanced Drug Delivery Nanosystems: Perspectives and Regulatory Issues 29. Towards the Development of a Device to Improve the Gait of Patients Suffering from Parkinson’s Disease 30. Developing Antisense Therapies for Neurodegenerative Diseases 31. Advances in Gene Therapies for the CNS 32. Nutrition and PD 33. Stem cell therapy in NDG disorders

About the Author :
Dr. Wael Mohamed is Professor of Basic Medical Science at the International Islamic University Malaysia. He obtained his MD and MSc in Clinical Pharmacology from Meoufia Medical School, Egypt, and his PhD in Neuroscience from The Pennsylvania State University. After finishing his neurosurgery training, he began his career as a clinical pharmacologist with psychopharmacology as a subspecialty. Dr. Mohamed specializes in translational brain research and brings more than two decades of experience to the project. His current focal area is the investigation and development of novel treatments for Alzheimer’s Disease and Parkinson’s Disease. He is a member of several key basic and clinical neuroscience societies, including the American Psychological Association, The Society for Neuroscience, National Academy of Neuropsychology, and the International Congress of Neuropsychopharmacology. Dr. Mohamed brings prior book editing experience from Elsevier titles including Pharmacotherapy of Parkinson’s Disease; Essential Guide to Neurodegenerative Disorders; Translational Models of Parkinson’s Disease and related Movement Disorders; and Telehealth in Movement Disorders.


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Product Details
  • ISBN-13: 9780443157028
  • Publisher: Elsevier Science Publishing Co Inc
  • Publisher Imprint: Academic Press Inc
  • Height: 235 mm
  • No of Pages: 700
  • Weight: 1880 gr
  • ISBN-10: 0443157022
  • Publisher Date: 28 Nov 2024
  • Binding: Paperback
  • Language: English
  • Sub Title: Mechanistic, Diagnostic and Therapeutic Advances
  • Width: 191 mm


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