Handbook of Endocannabinoid Function in the Central Nervous System
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Handbook of Endocannabinoid Function in the Central Nervous System: Volume 33(Volume 33 Handbook of Behavioral Neuroscience)

Handbook of Endocannabinoid Function in the Central Nervous System: Volume 33(Volume 33 Handbook of Behavioral Neuroscience)


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About the Book

Handbook of Endocannabinoid Function in the Central Nervous System, a new release in the Handbook of Behavioral Neuroscience series, offers a comprehensive, interdisciplinary approach to understanding the role of the endocannabinoid system in functions of the central nervous system. This new volume brings together the most influential and internally recognized experts in the field to provide a detailed overview of the physiological and pathophysiological roles of endocannabinoids in CNS activity. It covers the history, functional anatomy, and neurophysiology of the endocannabinoid system, moving on to assess endocannabinoid roles across human lifespans, and in behavioral control. Final sections of the book explore the use of endocannabinoids in psychiatric and neurological disorders. This is a vital resource for neuroscientists, neuropharmacologists, and neuropathologists, as well as any researcher seeking detailed discussions of brain endocannabinoid functions.

Table of Contents:
Section I – History of the endocannabinoid system 1. An insider view of the discovery of the endocannabinoid research 2. The endocannabinoid system: present, future 3. Medical chemistry of the eCB system Section II – Functional anatomy of the endocannabinoid system 4. The endocannabinoid signalosome 5. Endocannabinoid biosynthesis, degradation, and transport 6. Structure and distribution of endocannabinoids’ receptors 7. Endocannabinoid in glial cells 8. Endocannabinoid in non-neuronal cells of the CNS 9. Endocannabinoid – lipid interactions 10. Endocannabinoid and mitochondria 11. Sexual differences in the endocannabinoid system Section III – The neurophysiology of the endocannabinoid system 12. Cellular effects of endocannabinoid in the CNS 13. Endocannabinoids control of excitability: from neuron to networks 14. Endocannabinoids control of synaptic transmission: from neuron to networks 15. Endocannabinoids – pain modulation 16. Endocannabinoids regulation of striatal functions 17. Endocannabinoids regulation of hippocampal functions 18. Endocannabinoids regulation of the mesolimbic system 19. Endocannabinoids regulation of cortical functions 20. Endocannabinoids regulation of spino-cerebellar functions 21. Peripheral and central endocannabinoids in the regulation of metabolism Section IV – Endocannabinoids in development and lifetime 22. Roles of eCB in the fetal brain and early postnatal development 23. Roles of eCB in adolescence and sensitive periods 24. Roles of eCB in aging 25. Epigenetic control of eCB 26. Perinatal cannabinoid exposure Section V – Endocannabinoids and behavioral control 27. Endocannabinoids and sensory processing 28. Endocannabinoids in motor control 29. Role of the eCB system in appetite and eating behavior 30. Endocannabinoids and the neurobiology of emotional states 31. Endocannabinoids and social behavior 32. The role of endocannabinoids in impulsivity, compulsivity, and decision-making 33. Endocannabinoids in learning and memory 34. Endocannabinoids in cognition Section VI – Endocannabinoids in psychiatric disorders 35. Anxiety and depression 36. Endocannabinoids and schizophrenia 37. Endocannabinoid neurobiology in cannabis use disorder 38. The role of endocannabinoids in alcohol use and abuse 39. The role of endocannabinoids in psychostimulant addiction 40. The role of endocannabinoids in opioid abuse and addiction 41. Endocannabinoids in eating disorders 42. Endocannabinoids in autism spectrum disorder 43. Endocannabinoids in mental disorders 44. Endocannabinoids in OCD and Tourette’s Section VII – Endocannabinoids in neurological disorders 45. Endocannabinoids in Parkinson's disease and neurodegenerative diseases 46. Endocannabinoids in seizures and epilepsy 47. Endocannabinoids and stroke 48. Endocannabinoids and Alzheimer’s 49. Endocannabinoids and multiple sclerosis 50. Endocannabinoids and brain cancer

About the Author :
Olivier Manzoni is a Research Director at INSERM in Marseille and director of the International Associated Laboratory CannaLab (University of Indiana, Bloomington USA / Aix-Marseille University, France). His research is centered on understanding the molecular basis of synaptic plasticity in normal and pathological conditions, with a focus on the function of the endocannabinoid system and the effects of cannabis during lifetime. Vivana Trezza is an Associate Professor and Group Leader at Roma Tre University. Her research investigates the brain mechanisms underlying functional and dysfunctional socio-emotional behavior, to identify novel pharmacological targets for neuropsychiatric and neurodevelopmental disorders characterized by aberrant socio-emotional processing. A special emphasis in her research is placed on the role of the endocannabinoid system in the regulation of emotions and cognition through development.


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Product Details
  • ISBN-13: 9780443139086
  • Publisher: Elsevier Science Publishing Co Inc
  • Publisher Imprint: Academic Press Inc
  • Height: 276 mm
  • No of Pages: 500
  • Sub Title: Volume 33
  • ISBN-10: 0443139083
  • Publisher Date: 01 Nov 2025
  • Binding: Hardback
  • Language: English
  • Series Title: Volume 33 Handbook of Behavioral Neuroscience
  • Width: 216 mm


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Handbook of Endocannabinoid Function in the Central Nervous System: Volume 33(Volume 33 Handbook of Behavioral Neuroscience)
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Handbook of Endocannabinoid Function in the Central Nervous System: Volume 33(Volume 33 Handbook of Behavioral Neuroscience)
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