About the Book
This volume in the "Foundations in Diagnostic Pathology Series" packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you're getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice!
Table of Contents:
SECTION I. MOLECULAR PRINCIPLES Chapter 1 Molecular Biology Basics for the Pathologist, Ilka Warshawsky Chapter 2 Quality Assurance of Molecular Assays, Wayne W. Grody SECTION II. MOLECULAR TOOLS AND TECHNIQUES Chapter 3 Overview of Molecular Diagnostic Techniques and Instrumentation, Daniel H. Farkas and Carol A. Holland Chapter 4 Conventional and Real Time Polymerase Chain Reaction (PCR), Aaron Bossler and Vivianna Van Deerlin Chapter 5 Loss of Heterozygosity, Jennifer L. Hunt Chapter 6 Direct Genome Sequencing in Diagnostic Pathology, Gurunathan Murugesan and Gary W. Procop Chapter 7 Array-Based Comparative Genomic Hybridization in the Analysis of Genomic Alterations in Human Disease, Marek Skacel, Ana Ambu Siva, and Raymond R. Tubbs Chapter 8 Expression Arrays: Discovery and Validation, Neal Poulin and Torsten O. Nielsen Chapter 9 Epigenetics: DNA Hypermethylation in Cancer, Bin Yang Chapter 10 Tissue Microarrays, Ziad Peerwani Chapter 11 Fluorescence in Situ Hybridization, James R. Cook Chapter 12 Bright Field in Situ Hybridization, Ricardo V. Lloyd, Xiang Qian, and Long Jin Chapter 13 Immunoglobulin and T-Cell Receptor Gene Rearrangement, Margaret L. Gulley Chapter 14 Monitoring of Minimal Residual Hematologic Disease, Cuihong Wei, Jeffrey H. Lipton, and Suzanne Kamel-Reid Chapter 15 Molecular Detection of Circulating Tumor Cells, Karen L. Kaul Chapter 16 Intraoperative Molecular Staging Using Real-Time PCR, Tony E. Godfrey SECTION III. DIAGNOSTIC MOLECULAR PATHOLOGY APPLICATIONS Chapter 17, Molecular Cytopathology, Karen S. Gustafson and Douglas P. Clark Chapter 18 Molecular Diagnosis of Infectious Agents in Tissue, Randall T. Hayden and Gary W. Procop Chapter 19 Molecular Neuropathology, Richard Prayson Chapter 20 Molecular Pathology of the Cardiovascular System, Carmela D. Tan and E. Rene Rodriguez Chapter 21 Molecular Pulmonary Pathology, Samuel Yousem and Sanja Dacic Chapter 22 Molecular Dermatopathology, Alexander J.F. Lazar, Jason W. Nash, and Abdul Hafeez Diwan Chapter 23 Molecular Gastrointestinal, Liver, and Pancreatic Pathology, Rish K. Pai, Rebecca Wilcox, and John Hart Chapter 24 Molecular Endocrine Pathology, Jennifer L. Hunt Chapter 25 Molecular Hematopathology, James R. Cook Chapter 26 Molecular Pathology of Bone and Soft Tissue Tumors, Brian P. Rubin, Alexander J.F. Lazar, and Andre Oliveira Chapter 27 Molecular Pathology of Breast Cancer, David G. Hicks Chapter 28 Molecular Genitourinary Pathology, Donna E. Hansel, Cristina Magi-Galluzzi, and Ming Zhou Chapter 29 Molecular Gynecologic Pathology, Monica Prasad Hayes, Edyta C. Pirog, and Lora Hedrick Ellenson Chapter 30 Pediatric Molecular Pathology, Robin LeGallo
Review :
This book is a welcome addition to a growing list of clear, detailed and up-to-date books for the surgical pathologist in the 'Foundations in Diagnostic Pathology' series. Overall I found this a useful, interesting, engaging and relatively inexpensive book, and one that should be of interest to any surgical pathologist, regardless of their speciality given its wide coverage. I would particularly recommend it to trainee pathologists as a good introduction to what is likely to be a growing field during their careers. The Royal College of Pathologists, April 2009
