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Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Pharmacology > Pharmaceutics: The Science of Dosage Form Design
Pharmaceutics: The Science of Dosage Form Design

Pharmaceutics: The Science of Dosage Form Design


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About the Book

This textbook covers the design of dosage forms and all aspects of drug delivery systems. "Pharmaceutics" in its broadest sense is the "art of the apothecary" or, in simple terms, pharmaceutical preparations. It remains a diverse subject in the pharmacy curriculum, encompassing design of drugs, their manufacture and the elimination of micro-organisms from the products. This book encompasses all of those areas and pays particular attention to the design of dosage forms and their manufacture

Table of Contents:
Design of dosage forms. PART ONE SCIENTIFIC PRINICIPLES OF FORMULATION SCIENCE Solutions and their properties. Rheology and flow. Surface and interfacial phenomena. Solubility and dissolution rate. Disperse systems. Kinetics and product stability. PART TWO PARTICLE SCIENCE AND POWDER TECHNOLOGY Solid-state properties of powders. Particle size analysis. Particle size reduction. Particle size separation. Mixing. Powder flow. PART THREE BIOPHARMACEUTICS PRINCIPLES OF DRUG DELIVERY Introduction to Biopharmaceutics. Factors influencing bioavailability. Assessment of bioavailability. Dosage Regimens. Sustained and extended release. PART FOUR DOSAGE FORM DESIGN AND MANUFACTURE Preformulation. Solutions, Suspensions and Emulsions. Filtration. Powders and granules. Granulation. Drying. Tablets and compaction. Tablet coating. Capsules and encapsulation. Pulmonary drug delivery. Nasal delivery. Rectal and vaginal delivery. Parenteral products. Transdermal drug delivery. Delivery of proteins/biotech products. Packs and packaging. Materials of fabrication and corrosion. Heat transfer and the properties of steam. PART FIVE PHARMACEUTICAL MICROBIOLOGY AND STERILIZATION Fundamentals of microbiology. The action of physical and chemical agents on micro-organisms. Microbiological contamination and preservation. Principles of sterilization. Sterilization practice. Design and operation of clean rooms.

Review :
"Aulton's 'Pharmaceutics' is essential reading for every pharmacy student. It makes a very diverse, dry subject area into a comprehensible, more attractive one in just one test. It is clearly written at an appropriate level for both those new to the subject area and those more advance. It is both informative and descriptive, providing a basic understanding of pharmaceutics which is vital to all pharmacists and pharmaceutical scientists...The high recommendations of Aulton 'Pharmaceutics' by both lecturers and peers are clearly justified." 3rd Year Pharmacy Student, Welsh School of Pharmacy, Cardiff, March 2004


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Product Details
  • ISBN-13: 9780443055171
  • Publisher: Elsevier Health Sciences
  • Publisher Imprint: Churchill Livingstone
  • Edition: Revised edition
  • Language: English
  • Spine Width: 32 mm
  • Weight: 840 gr
  • ISBN-10: 0443055173
  • Publisher Date: 30 Oct 2001
  • Binding: Paperback
  • Height: 248 mm
  • Returnable: N
  • Sub Title: The Science of Dosage Form Design
  • Width: 191 mm


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