Kucers' The Use of Antibiotics Sixth Edition: A Clinical Review of Antibacterial, Antifungal and Antiviral Drugs

'I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics

Table of Contents:
Volume I Section I - ANTIBIOTICS Part - 1 Penicillins and Related Drugs Benzylpenicillin (Penicillin G) Phenoxypenicillins Ampicillin, Amoxicillin and Other Ampicillin-Like Penicillins Methicillin Isoxazolyl Penicillins: Oxacillin, Cloxacillin, Dicloxacillin and Flucloxacillin Nafcillin Carbenicillin, Carindacillin, Carfecillin and Ticarcillin Mezlocillin, Azlocillin, Apalcillin and Piperacillin Mecillinam (Amdinocillin) and Pivmecillinam Temocillin Beta-Lactamase Inhibitors and Combinations Clavulanic Acid Sulbactam Tazobactam and Brobactam Amoxicillin–Clavulanic Acid (Co-Amoxiclav) Ampicillin–Sulbactam Ticarcillin–Clavulanic Acid Piperacillin–Tazobactam Part - 2 Cephalosporins and Related Drugs Cephalothin and Cefazolin Cephalexin Cephadroxil, Cephaloridine, Cephacetrile, Cephapirin, Cephradine, and Other Rarely Used First-Generation Cephalosporins Cefaclor, Cefprozil, and Loracarbef Cefuroxime Cefotiam, Cefuzonam, Cefamandole, Cefonicid and Ceforanide Cefoxitin, Cefotetan and Other Cephamycins (Cefmetazole and Flomoxef) Cefoperazone and Cefoperazone–Sulbactam Cefotaxime Ceftriaxone Ceftizoxime, Cefdinir, Cefditoren, Cefpodoxime, Ceftibuten, Cefsulodin, and Cefpiramide Cefixime Ceftazidime Cefpirome Cefepime Ceftaroline Ceftobiprole Aztreonam Part - 3 Carbapenems Imipenem Meropenem Doripenem Ertapenem Biapenem Faropenem Panipenem Ritipenem Sulopenem Part - 4 Glycopeptides and Lipopeptides Vancomycin Teicoplanin Daptomycin Oritavancin Dalbavancin Telavancin Ramoplanin Part - 5 Aminoglycosides Kanamycin Gentamicin Tobramycin Amikacin Sisomicin and Netilmicin Isepamicin Neomycin Part - 6 Macrolides and Ketolides Erythromycin Roxithromycin Clarithromycin Azithromycin Josamycin and Rosaramicin Telithromycin Cethromycin Part - 7 Tetracyclines and Related Drugs Tetracycline Doxycycline Minocycline Tigecycline Part - 8 Other Antibiotics Linezolid Quinupristin–Dalfopristin Pristinamycin Fosfomycin Fusidic Acid (Fusidate Sodium) Polymyxins Novobiocin Bacitracin and Gramicidin Mupirocin Lincomycin and Clindamycin Chloramphenicol and Thiamphenicol Spectinomycin Part - 9 Anti-Folate Agents and Other Synthetic Antibacterials Sulfonamides Trimethoprim, Co-Trimoxazole (Co-T) and Related Agents Pyrimethamine Dapsone Trimetrexate Iclaprim Nitrofurans: Nitrofurazone, Furazolidone and Nitrofurantoin Methenamine Mandelate and Methenamine Hippurate Part - 10 Nitroimidazoles Metronidazole Tinidazole Part - 11 Quinolones and Fluoroquinolones Nalidixic Acid and Other Older Quinolones Ciprofloxacin Norfloxacin Ofloxacin Levofloxacin Moxifloxacin Gatifloxacin Garenoxacin Gemifloxacin Sitafloxacin Enoxacin Pefloxacin Sparfloxacin Lomefloxacin Rufloxacin Tosufloxacin Fleroxacin Newer, Discontinued Fluoroquinolones: Temafloxacin, Trovafloxacin, Grepafloxacin, and Clinafloxacin Part - 12 Anti-Tuberculous Drugs Isoniazid Ethambutol Pyrazinamide Rifampicin (Rifampin) Rifabutin Rifaximin Rifapentine Streptomycin Para-Aminosalicylic Acid (PAS) Ethionamide and Prothionamide Thiacetazone Capreomycin Cycloserine Viomycin Volume 2 Section II - ANTI-FUNGAL DRUGS Part - 1 Polyenes Amphotericin B (AMP): Deoxycholate and Lipid Formulations Nystatin Natamycin (Pimaricin) Part - 2 Echinocandins, Allylamines and Benzylamine Derivatives Echinocandins – Caspofungin, Anidulafungin and Micafungin Terbinafine Butenafine Naftifine Part - 3 Systemic Azoles Ketoconazole Fluconazole Itraconazole Miconazole Voriconazole Posaconazole Ravuconazole Albaconazole Isavuconazole Part - 4 Topical Azoles Bifonazole Butoconazole Clotrimazole Croconazole Eberconazole Econazole Enilconazole Fenticonazole Flutrimazole Isoconazole Lanoconazole Neticonazole Oxiconazole Sertaconazole Sulconazole Terconazole Tioconazole KP-103 Part - 5 Topical Agents - Thiocarbamates, Hydroxypridones and Morpholine Tolnaftate Amorolfine Ciclopirox Rilopirox Part - 6 Other Antifungal Agents and New Agents in Development Flucytosine (5-Fluorocytosine; 5-FC) Griseofulvin Haloprogin New Agents in Development – Nikkomycin Z, CAY-1, Sodarins, Butenolides, Enfungumab, Inositol Phosphoceramide Synthase Inhibitors Section III Anti - Parasitic Drugs Part - 1 Anti-Malarial Agents Chloroquine Amodiaquine Quinine and Quinidine Mefloquine Halofantrine Lumefantrine Primaquine Piperaquine Tafenoquine Atovaquone Proguanil and Chloroproguanil Artemisinins Part - 2 Agents Active Against Intestinal and Intra-Abdominal Protozoa Iodoquinol and Quinacrine Fumagillin Furazolidone (Furazolidine) Diloxanide Furoate Spiramycin Nitazoxanide Paromomycin Part - 3 Agents Active Against American Trypanosomiasis Benznidazole Nifurtimox Part - 4 Agents Active Against African Trypanosomiasis Suramin Melarsoprol Eflornithine Part - 5 Agents Active Against Leishmania and Other Pathogens Pentamidine Antimonial Agents Miltefosine Part - 6 Agents Active Against Helminths Albendazole Mebendazole Thiabendazole Triclabendazole Ivermectin Diethylcarbamazine (DEC) Pyrantel Pamoate Praziquantel Oxamniquine Metrifonate Niclosamide Part - 7 Agents Active Against Ectoparasites Permethrin Piperonyl Butoxide Lindane Malathion Crotamiton Section IV ANTI-VIRAL DRUGS Part - 1 Agents Active Against Herpesviruses Aciclovir Valaciclovir Famciclovir and Penciclovir Ganciclovir and Valganciclovir Cidofovir Vidarabine Foscarnet Maribavir Trifluridine (Trifluorothymidine) Idoxuridine Fomivirsen Part - 2 Agents Active Against the Human Immunodeficiency Virus Inhibitors of Reserve Transcriptase Zidovudine Didanosine Zalcitabine Lamivudine Stavudine (d4T) Abacavir Emtricitabine Tenofovir Amdoxovir Apricitabine Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) Nevirapine Efavirenz Delavirdine Etravirine Rilpivirine Inhibitors of HIV Protease Saquinavir Ritonavir Indinavir Nelfinavir Lopinavir Amprenavir and Fosamprenavir Darunavir Atazanavir Tipranavir Other Anti-HIV Agents Enfuvirtide Maraviroc Raltegravir and Other HIV Integrase Inhibitors Part - 3 Agents Active Against Hepatitis Viruses Entecavir Adefovir Dipivoxil Telbivudine Torcitabine and Valtorcitabine Clevudine Ribavirin and Viramidine Pegylated Interferon Alfa Protease and Polymerase Inhibitors for the Treatment of Hepatitis C Virus Infection Part - 4 Agents Active Against Respiratory Viruses Amantadine and Rimantadine Zanamivir and Polymeric Zanamivir Conjugates Oseltamivir Peramivir

About the Author :
M Lindsay Grayson MB BS MD MSC FRACP FRCP FAFPHM Professor of Medicine and Director, Infectious Disease and Microbiology Departments, Austin Health Department of Epidemiology and Preventative Medicine, Monash University Department of Medicine, University of Melbourne, Melbourne, Australia Section Editors: Suzanne M Crowe, James S McCarthy, John Mills, Johan W Mouton, S Ragnar Norrby, David L Paterson, Michael A Pfaller

Review :
In keeping with its well-earned reputation as the leading and absolute authority on antibiotics, Kucers' remains a must-have for infectious diseases clinicians. Clinical Infectious Disease 2011 This sixth edition of Kucers' The Use of Antibiotics is one of the most updated comprehensive compendiums on this subject. The book is a must in all hospitals and medical libraries. Expert Rev. Anti Infect. Ther 2011