About the Book
A Handbook of Artificial Intelligence in Drug Delivery explores the use of Artificial Intelligence (AI) in drug delivery strategies. The book covers pharmaceutical AI and drug discovery challenges, Artificial Intelligence tools for drug research, AI enabled intelligent drug delivery systems and next generation novel therapeutics, broad utility of AI for designing novel micro/nanosystems for drug delivery, AI driven personalized medicine and Gene therapy, 3D Organ printing and tissue engineering, Advanced nanosystems based on AI principles (nanorobots, nanomachines), opportunities and challenges using artificial intelligence in ADME/Tox in drug development, commercialization and regulatory perspectives, ethics in AI, and more.
This book will be useful to academic and industrial researchers interested in drug delivery, chemical biology, computational chemistry, medicinal chemistry and bioinformatics. The massive time and costs investments in drug research and development necessitate application of more innovative techniques and smart strategies.
Table of Contents:
1. An overview of Artificial intelligence in Drug development
2. General considerations on Artificial intelligence
3. Role of Artificial intelligence in quality profiling and optimization of drug products
4. AI application in the drug manufacturing for multivariate control
5. AI approaches for the development of drugs and delivery systems
6. Artificial neural network (ANN) in Drug delivery
7. Relevance of AI in Microbased Drug delivery system
8. Application of Artificial Intelligence driving Nano-based Drug Delivery System
9. AI in Microfabrication technology
10. Tracing the Nose-to-brain Nanoparticulate drug delivery using Bio /chemoinformatics tools
11. Applicability of machine learning in three-dimensionally (3D) printing dosage forms
12. Role of AI in ADME/Tox towards formulation optimization and delivery
13. Self-regulated Drug delivery Micro/ Nanodevice
14. Design and application of Nanorobots in Targeted drug delivery
15. Role of AI in Drug Product Designing, Development & Manufacturing
16. Impact of AI on drug delivery and pharmacokinetics: The present scenario and future prospects
17. Artificial Intelligence in Vaccine Development: Significance and Challenges Ahead
18. AI-enabled Qadrupole Stimuli-Responsive Targeted Polymeric Nano drug delivery for Cancer Therapy
19. Convergence of Artificial Intelligence and Nanotechnology in the Development of Novel Formulations for Cancer
20. Artificial Intelligence in Precision Medicine
21. Artificial Intelligence and Machine Learning in Clinical Trial Design & Application
22. Artificial Intelligence from regulatory perspective: Drug delivery and devices
About the Author :
Dr. Anil Philip is currently working as Associate Dean (Head), School of Pharmacy, University of Nizwa, Oman. Among other credentials, he served as a member of the Health and Social Sciences sectorial grant committee of The Research Council, Oman, and as Faculty Mentored Undergraduate Research Program general supervisor to promote undergraduate research at the University of Nizwa. His research objectives and achievements have been in controlling/modifying the release of small/large molecules targeted to GI space using phase-transited delivery systems. He has worked extensively in the field of controlled/ modified drug release systems. Currently, his research focuses on developing nano-drug delivery systems, which can be targeted to the various body organs. He has guided students in areas of targeted drug delivery, has more than 40 original research publications in international peer-reviewed journals, and two patents on drug delivery systems. Dr. Aliasgar Shahiwala is currently serving as a Professor in the Department of Pharmaceutics, and Graduate Program Director, at Dubai Pharmacy College, Dubai, UAE. He received his MA and PhD in pharmaceutics and pharmaceutical technology from the Maharaja Sayajirao University of Baroda, India, with a particular research focus on the area of novel drug delivery. His postdoctoral research at Northeastern University, USA, centered on applications of nanotechnology in the field of drug delivery and drug targeting. With more than 20 years of teaching and research experience, Prof. Shahiwala has published several articles in international peer-reviewed journals, edited 4 books, and authored many book chapters, as well as being an active reviewer and editorial board member. Dr. Mamoon Rashid serves the college as Assistant Professor of Pharmaceutics at Appalachian College of Pharmacy, Oakwood, Virginia, USA. After finishing his PhD in Pharmaceutical Sciences from Texas Tech University Health Sciences Center, he joined the Appalachian College of Pharmacy in October 2013. His doctoral research work discovered that the endopeptidase neurolysin is associated to stroke pathology, and remains a potential consideration for developing therapeutics. Recently, Dr. Rashid has contributed two chapters for a book on Bioinspired and Biomimetic Materials for Drug Delivery (Woodhead, Oct 2016). Dr. Rashid’s research interest includes both drug delivery and molecular biology. His current projects included development of transdermal drug delivery and stability of marketed drug products and development of analytical method of different products compounded in local pharmacies. Md Faiyazuddin stands out as a leading figure in pharmacy education and research, distinguished by his comprehensive background and contributions to the field. Renowned for his prolific contributions to the field, Dr. Faiyazuddin is an avid researcher, delving into various facets of formulation science. As the founder Dean R&D at Al – Karim University and a Professor of Pharmaceutics, he is at the forefront of health and drug delivery research. With 18 years of experience, Dr. Faiyazuddin is currently the founder Dean R&D and Professor of Pharmaceutics at Al – Karim University. Previously, he served as Dean and Professor at The R. C. University, Principal at Bihar College of Pharmacy, and held various academic and research positions at the University of Hail and Integral University. He is advising Nano Drug Delivery® USA (A product development partnership company) for product development, optimization, and scale-up of Nanopharmaceutical. Holding a PhD in Pharmaceutics from Jamia Hamdard, New Delhi, India, Dr. Faiyazuddin specializes in pharmaceutical nanotechnology and earned an executive strategic leadership management degree at the Jacobs-Abbey Global Institute for Leadership Studies, Woodbridge, Virginia, USA. He has extensive research experience in pharmaceutical nanotechnology, advanced drug delivery, marine bioactive, and recently pharmaceutical AI and probiotics medicines. He is a visiting scientist and adjunct professor of reputed universities at the national as well as international level sharing outstanding ideas and cutting-edge technologies with laureates in health and the pharmaceutical sectors.
He serves as an editorial board member and reviewer for several high-impact international scientific journals published by Lancet, Cell press, Elsevier, ACS, Springer Nature, RSC, Taylor and Francis, Cambridge, and John Wiley. His scholarly contributions are substantial, with over 150 peer-reviewed articles published in top-tier journals such as ACS, Elsevier, and Wiley, alongside 9 patents, 12 books, and 62 book chapters. He has been recognized with 8 awards, including the DST Young Scientist Award (2012), Dr. P.D. Sethi Award (2010), and the Global Peace Building Award (2023). Additionally, he holds 7 fellowships, has chaired 15 editorial boards and conferences, and delivered over 50 invited conference presentations.
He has secured and effectively managed research grants from several prominent research and development agencies. These include SERB-DST, as well as international bodies such as DSR-UoH-KSA, NJ-KSA, KAUST, UiTM Malaysia, and SickKids Hospital in Canada. The total value of these grants exceeds Rs. 1.12 Million INR, underscoring his ability to attract and successfully execute high-profile research projects. His expertise in attracting and executing high-profile research projects is well demonstrated. Additionally, he has developed and implemented innovative educational tools and programs that address critical needs in diverse and underserved communities, advancing both scientific research and educational access.
