Advances in Perinatal Medicine by E. Friedman - Bookswagon
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Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Gynaecology and obstetrics > Advances in Perinatal Medicine: Volume 5
Advances in Perinatal Medicine: Volume 5

Advances in Perinatal Medicine: Volume 5


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About the Book

The state of health care is reflected by perinatal and neonatal morbidity and mortality as well as by the frequencies of long-term neurologic and developmental disorders. Many factors, some without immediately rec- ognizable significance to childbearing and many still unknown, undoubt- edly contribute beneficially or adversely to the outcome of pregnancy. Knowledge concerning the impact of such factors on the fetus and sur- viving infant is critical. Confounding analyses of pregnancy outcome, especially these past two or three decades, are the effects of newly un- dertaken invasive or inactive therapeutic approaches coupled with the advent of high technology. Many innovations have been introduced with- out serious efforts to evaluate their impact prospectively and objectively. The consequences of therapeutic misadventures characterized the past; it seems they have been replaced to a degree by some of the complications of applied technology. Examples abound: after overuse of oxygen was recognized to cause retrolental fibroplasia, its restriction led to an in- crease in both neonatal death rates and neurologic damage in surviving infants. Administration of vitamin K to prevent neonatal hemorrhagic disease, particularly when given in what we now know as excessive dos- age, occasionally resulted in kernicterus. Prophylactic sulfonamide use had a similar end result. More recent is the observation of bronchopul- monary dysplasia as a complication of respirator therapy for hyaline membrane disease.

Table of Contents:
1 Nutritional Supplementation of the Growth-Retarded Fetus: Rationale, Theoretical Considerations, and in Vivo Studies.- 1. Introduction.- 2. Rationale for Considering Nutritional Therapy.- 2.1. Normal Fetal Growth and Nutrition—A Brief Review.- 2.2. The Growth-Retarded or Small-for-Gestational-Age Infant.- 2.3. Summary of Rationale for Supplementation.- 3. Theoretical Considerations in Providing Nutritional Supplementation.- 3.1. Potential Toxicity.- 3.2. Routes of Supplementation.- 4. Fetal Nutritional Supplementation: Human and Animal Studies.- 4.1. Supplementation via Intra-amniotic Administration of Nutrients.- 4.2. Supplementation via Gastrointestinal Administration of Nutrients.- 4.3. Supplementation via Intravascular Administration of Nutrients.- 4.4. Utilization of Administered Nutrients.- 5. Conclusions.- References.- 2 Transplacental Toxicity of Environmental Chemicals: Environmental Causes and Correlates of Spontaneous Abortions, Malformations, and Childhood Cancer.- 1. Introduction.- 2. Environmental Chemicals and Spontaneous Abortions.- 2.1 Occupational and Social Correlates of Spontaneous Abortions.- 2.2. Health Care Personnel.- 2.3. Laboratory Workers and Solvents.- 2.4. Workers in the Metals Industry.- 2.5. Workers in the Chemicals and Plastics Industry.- 2.6. Workers in the Rubber Industry.- 2.7. 2,4,5-T and TCDD.- 2.8. Other Occupational Groups.- 2.9. Air Pollution.- 3. Environmental Chemicals and Malformations.- 3.1. Occupational and Social Correlates of Malformations.- 3.2. Health Care Personnel.- 3.3. Laboratory Work and Solvents.- 3.4. Metals Industry.- 3.5. Methylmercury.- 3.6. Kanechlor (Polychlorinated Biphenyls).- 3.7. Potato Blight.- 3.8. Soft Water.- 3.9. 2,4,5-T and TCDD.- 3.10. Vinyl Chloride.- 3.11. Water Fluoridation.- 4. Parental Occupation and Cancer in the Offspring.- 5. Conclusions.- References.- 3 Neonatal Polycythemia and Hyperviscosity.- 1. Introduction.- 2. Definition.- 3. Incidence.- 4. Viscosity.- 4.1. Definition.- 4.2. Factors Affecting in Vitro Viscosity Measurements.- 4.3. Factors Affecting Blood Viscosity in Vivo.- 5. Hemodynamic Changes in Polycythemic and Hyperviscous States.- 5.1. Cardiopulmonary Blood Flow.- 5.2. Gastrointestinal Blood Flow.- 5.3. Renal Blood Flow.- 5.4. Carcass Blood Flow.- 5.5. Brain Blood Flow.- 5.6. Fetal Blood Flow.- 6. Etiology.- 7. Clinical Symptoms.- 7.1. Blood Volume and Body Water.- 7.2. Cardiopulmonary Symptoms.- 7.3. Gastrointestinal Symptoms.- 7.4. Renal Function.- 7.5. Hypoglycemia.- 7.6. Hematologic Complications.- 7.7. Neurologic Manifestations.- 8. Management.- References.- 4 Maternal Psychoactive Substance Use and Its Effect on the Neonate.- 1. Introduction.- 1.1. Methodologic Considerations.- 1.2. Studies in Animals.- 2. Cigarette Smoking.- 2.1. Introduction.- 2.2. Pharmacology.- 2.3. Studies in Animals.- 2.4. Studies in Humans.- 2.5. Summary.- 3. Caffeine.- 3.1. Introduction.- 3.2. Pharmacology.- 3.3. Studies in Animals.- 3.4. Studies in Humans.- 3.5. Summary.- 4. Alcohol.- 4.1. Introduction.- 4.2. Pharmacology.- 4.3. Studies in Animals.- 4.4. Studies in Humans.- 4.5. Prenatal Intervention.- 4.6. Summary.- 5. Marijuana Use.- 5.1. Introduction.- 5.2. Pharmacology.- 5.3. Studies in Animals.- 5.4. Studies in Humans.- 5.5. Summary.- 6. Opiate Use.- 6.1. Introduction.- 6.2. Pharmacology.- 6.3. Studies in Animals.- 6.4. Studies in Humans.- 6.5. Follow-up Studies.- 6.6. Prenatal Intervention.- 6.7. Summary.- 7. Amphetamines.- 7.1. Introduction.- 7.2. Pharmacology.- 7.3. Studies in Animals.- 7.4. Studies in Humans.- 7.5. Summary.- 8. Cocaine.- 8.1. Introduction.- 8.2. Pharmacology.- 8.3. Studies in Animals.- 8.4. Studies in Humans.- 9. Barbiturates.- 9.1. Introduction.- 9.2. Pharmacology.- 9.3. Studies in Animals.- 9.4. Studies in Humans.- 9.5. Summary.- 10. Phencyclidine.- 10.1. Introduction.- 10.2. Pharmacology.- 10.3. Studies in Animals.- 10.4. Studies in Humans.- 11. Diazepam.- 11.1. Introduction.- 11.2. Pharmacology.- 11.3. Studies in Animals.- 11.4. Studies in Humans.- 11.5. Summary.- 12. Summary.- References.- 5 Effect of Maternally Administered Drugs on the Fetus and Newborn.- 1. Introduction.- 2. Background Information.- 2.1. Maternal Physiologic Considerations.- 2.2. Drug Effects on the Uteroplacental Blood Flow.- 2.3. Placental Transfer of Drugs.- 2.4. Fetal Monitoring during Labor.- 2.5. Newborn Examinations.- 3. Methods of Pain Relief.- 3.1. Vaginal Delivery.- 3.2. Cesarean Delivery.- 4. Anesthesia and the Compromised Fetus.- 5. Relationship of Obstetric Anesthesia to Long-Term Neonatal Effects.- References.- 6 Chlamydial Infection.- 1. Introduction.- 2. Organism.- 3. Epidemiology.- 4. Perinatal Infections.- 4.1. Perinatal Outcome.- 4.2. Postpartum Endometritis.- 5. Neonatal Infections.- 5.1. Conjunctivitis.- 5.2. Pneumonia.- 5.3. Other Infections.- 6. Diagnosis.- 7. Therapy.- 7.1. Neonatal Eye Prophylaxis.- 7.2. Neonatal Treatment.- 7.3. Maternal Treatment.- References.


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Product Details
  • ISBN-13: 9780306423314
  • Publisher: Kluwer Academic Publishers Group
  • Publisher Imprint: Kluwer Academic / Plenum Publishers
  • Language: English
  • Returnable: Y
  • Weight: 550 gr
  • ISBN-10: 0306423316
  • Publisher Date: 30 Sep 1986
  • Binding: Hardback
  • No of Pages: 298
  • Sub Title: Volume 5


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