Cellular Biophysics
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Book 2
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Book 1
Book 2
Book 3
Book 1
Book 2
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Book 1
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Cellular Biophysics

Cellular Biophysics


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About the Book

Table of Contents:
Units, physical constants, and symbols. Part 1 Introduction to electrical properties of cells: a brief historical perspective; cellular electric potentials; mechanisms of generation of membrane potentials; role of electric potentials in information coding; the marvellous giant axon of the squid. Part 2 Lumped-parameter and distributed-parameter models of cells: electrical variables; electrically small cells; electrically large cells - the core conductor model; summary - a comparison of small and large cells. Part 3 Linear electrical properties of cells: elec-trical properties of cellular membranes; electrically small cells; electrically large cells - the cable model; summary - a comparison of small and large cells. Part 4 The Hodgkin-Huxley model: revelation of ionic mechanisms by the voltage-clamp technique; synthesis of the Hodgkin-Huxley model; explanation of the electrical excitability of the giant axon of the squid; appendices: properties of nonlinear, time-varying conductors; passive, nonlinear, time-invariant con-ductors; passive, non-linear, time-varying conductors. Part 5 Saltatory conduction in myelinated nerve fibres: structure of myelinated nerve fibres; physiological evidence for saltatory conduction; electrical properties of myelinated nerve fibres; model of saltatory conduction in myelinated nerve fibres; conduction velocity of myelinated nerve fibres; causes of saltatory conduction. Part 6 Voltage-gated ion channels: historical perspective; macroscopic ionic currents; gating currents; ionic currents in single channels; model of a voltage-gated channel with one two-state molecular gate; models of multiple-state channels; voltage-gated ion channel macromolecules; appendices: Markov process models of single channels; specific channel kinetic schemes.

Review :
"In this two volume series Weiss lays the foundations of cellular biophysics on physical principles in a framework that should be easily accessible to any student with a basic understanding of calculus and differential equations. The extensive set of thoughtful problems provided with each chapter will be invaluable in solidifying the student's understanding. I think it will be tremendous fun to teach from these texts." --Murray B. Sachs, Massey Professor and Director, Department of Biomedical Engineering, Johns Hopkins University "This beautiful treatment of cellular biophysics is a landmark. It is comprehensive, scholarly, interesting and clear as a bell. Everyone seriously interested in how cells do business with their surroundings will want to read it." --Charles F. Stevens, The Salk Institute


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Product Details
  • ISBN-13: 9780262231831
  • Publisher: MIT Press Ltd
  • Publisher Imprint: MIT Press
  • Height: 229 mm
  • Returnable: N
  • Spine Width: 48 mm
  • Weight: 1475 gr
  • ISBN-10: 0262231832
  • Publisher Date: 06 Mar 1996
  • Binding: Hardback
  • Language: English
  • Series Title: Bradford Books
  • Sub Title: v. 1
  • Width: 203 mm


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