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Immune Sera

Immune Sera


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Purchase of this book includes free trial access to www.million-books.com where you can read more than a million books for free. This is an OCR edition with typos. Excerpt from book: BACTERIOLYSINS AND HEMOLYSINS Historical. ? As far back as 1874, Gscheidlen and Traube 1 demonstrated that considerable quantities of septic material could be injected into the circulation of warm-blooded animals without apparently any effect on the animal. Very little was thought of this observation at the time, and it is not until more than ten years later that we find a similar observation made by Fodor.2 In 1888 Nuttall3 showed that normal blood serum possessed marked germicidal properties, and his observations stimulated a number of workers who undertook to determine the conditions most favorable to the exhibition of this phenomenon, and further to decide upon the constituent of the serum to which this property was due or whether it 'was a function of the serum as a whole. In 1899 Buchner4 published a series of experiments and showed that an exposure of ssC. robs the serum of its bactericidal property. He also concluded that the active element in the process was a living albumin andsuggested for it the name alexin. He found that it was possible to greatly increase the bactericidal action, (i.e. the quantity of alexin ) for a particular bacterium by immunizing an animal with that bacterium. 1 Gscheidlen and Traube. Schlez. Gesellschaft. f. Vater- land. Cultur, Med. Sect., 1874. Fodor, Deutsche med. Wochenschr, 1886. 3 Nutall, Zeitschr. f. Hygiene, Vol. iv, 1888. 4 Buchner, Centralblatt Bacteriologie, Vol. v, 1889. Archiv. f. Hygiene, Vol. x, 1890. Pfeiffer's Phenomenon. ? An enormous advance in the study of immunity was made in the discovery of Pfeiffer's phenomenon in 1894, and it is to Pfeiffer's splendid observations that, we owe the first and most important insight into the mode of action of the bacteriolytic immune sera. A normal guinea pig is ab...


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Product Details
  • ISBN-13: 9780217230018
  • Publisher: Rarebooksclub.com
  • Publisher Imprint: Rarebooksclub.com
  • Height: 246 mm
  • No of Pages: 46
  • Spine Width: 3 mm
  • Width: 189 mm
  • ISBN-10: 0217230016
  • Publisher Date: 08 Jul 2012
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Weight: 100 gr


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