Genome Mapping
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Genome Mapping

Genome Mapping


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About the Book

Genome analysis has undergone a period of explosive growth in recent years. This book describes up-to-date methods for genome mapping, arranged in order of increasing resolution, from linkage analysis to restriction mapping. Topics covered include linkage mapping of human, animal, and plant genomes; mapping of quantitative trait loci; radiation hybrid mapping; HAPPY mapping; somatic cell hybrids; flow-sorted and microdissected chromosomes; fluorescence in situ hybridization; contig assembly; chromosome walking; and long-range restriction mapping. Two appendices describe sources of freely available biological and computational resources relevant to genome analysis.

Table of Contents:
1: Human linkage mapping. 2: Linkage mapping of plant and animal genomes. 3: Linkage mapping of quantitative trait loci in plants and animals. 4: Radiation hybrid mapping. 5: HAPPY mapping. 6: Construction and use of somatic cell hybrids. 7: The use of flow-sorted chromosomes in genome mapping. 8: The use of microdissected chromosomes in genome mapping. 9: Fluorescence in situ hybridization. 10: Contig assembly by fingerprinting. 11: Chromosome wallking. 12: Long-range restriction mapping of genomic DNA. Appendix 1 Core list of suppliers. Appendix 2 Non-commercial source for genome mapping. Appendix 3 Bioinformatics for genome mapping

Review :
"All topics are presented in an easy-to-use format, with detailed step-by-step protocols...With this book, a researcher can carry out the most sophisticated array of analytical techniques currently available....In addition to the detailed protocols, the book also contains two valuable appendixes."--Doody's Journal ****


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Product Details
  • ISBN-13: 9780199636310
  • Publisher: Oxford University Press
  • Binding: Hardback
  • Returnable: N
  • ISBN-10: 0199636311
  • Publisher Date: 01 Oct 1997
  • Language: English


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Genome Mapping
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